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Gastrulation

Current Opinion in Genetics & Development, 1991
At gastrulation, a single layer of cells is converted into an outer ectodermal covering, an inner ectodermal tube, and in triploblastic phyla, a middle mesodermal layer. This morphogenesis is driven by motility and directed by cell interactions, some of which involve adhesion and others that involve information transfer.
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Vertebrate gastrulation

Current Opinion in Genetics & Development, 1992
Our understanding of the mechanisms that control gastrulation is still in its infancy. One problem is that gastrulation is a complex set of coordinated behaviours involving directional cell movements, several types of cell interactions, changes in cell fate and gene expression.
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Gastrulation and Split Cord Malformation

2023
Split cord malformation (SCM) is a rare form of closed spinal dysraphism, in which two hemi-cords are present, instead of a single spinal cord. SCM is categorised into type 1 and type 2. Type 1 SCM is defined by the presence of a bony or osseocartilaginous spur between the hemi-cords, whereas type 2 SCM has no bony spur, and the two hemi-cords are ...
Zubair, Tahir, Claudia, Craven
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Homeobox genes in vertebrate gastrulation

Current Opinion in Genetics & Development, 1995
The formation and anteroposterior patterning of the three definitive germ layers, ectoderm, or epiblast, is the common theme of vertebrate gastrulation. What changes from system to system is the geometry of these events and the nature of the non-epiblast transient structures implicated.
BONCINELLI E, Mallamaci, Antonio
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Human Pre-gastrulation Development

2018
Understanding the progression of early human embryonic development prior to implantation is of fundamental biological importance. Greater insights into early developmental events may lead to clinical improvements, not only via the establishment of novel stem cell models with increased potential or more physiological relevance, but also by uncovering ...
Sissy E, Wamaitha, Kathy K, Niakan
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Gastrulation in Drosophila

Seminars in Developmental Biology, 1994
The three germ layers in Drosophila are established by both the invagination of the ventral furrow, which internalizes the anterior midgut and mesoderm primordia, and the invagination of the posterior midgut primordium. The invaginations of these primordia occur by similar cell shape changes.
Reuter, R.   +1 more
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Cell migration during gastrulation

Current Opinion in Cell Biology, 2005
As the gateway to shaping the body plan, gastrulation is an important problem in developmental biology, and recent advances in cell biology have overcome some of the limitations of past approaches to learning how genes control reshaping of embryonic tissues.
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Movements of chick gastrulation

2020
In birds as in all amniotes, the site of gastrulation is a midline structure, the primitive streak. This appears as cells in the one cell-thick epiblast undergo epithelial-to-mesenchymal transition to ingress and form definitive mesoderm and endoderm. Global movements involving tens of thousands of cells in the embryonic epiblast precede gastrulation ...
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Gastrulating Cells Toddle

Science Signaling, 2014
A secreted peptide promotes gastrulation movements in zebrafish.
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