Results 161 to 170 of about 46,185 (207)

Immunohistochemical Subclassification of Peripheral T Cell Lymphomas-Not Otherwise Specified

open access: yesSouth Asian Journal of Cancer
Keerthana Chandran   +2 more
doaj   +1 more source

Molecular alterations in the GATA-2, RUNX1, C/EBPα and hTERT genes in patients with aplastic anemia by MLPA. [PDF]

open access: yesGenet Mol Biol
Salas IM   +10 more
europepmc   +1 more source

Differential expression of GATA-3 in urothelial carcinoma variants

Human Pathology, 2014
GATA binding protein 3 (GATA-3) is a novel immunohistochemical marker for urothelial carcinoma (UC); however, few studies have investigated GATA-3's role as a marker for UC variants. We used immunohistochemistry to assess GATA-3 expression in different UC variants, including micropapillary (n = 46), sarcomatoid (n = 43), small cell carcinoma (n = 22 ...
Ashish M Kamat   +2 more
exaly   +3 more sources

Role of GATA-3 in Allergic Diseases

Current Molecular Medicine, 2008
GATA-3 is a transcription factor that is specifically expressed in T helper 2 (Th2) cells and plays a critical role in the differentiation of Th2 cells from uncommitted CD4+ lymphocytes. In addition GATA-3 is essential for the gene expression of the cytokines IL-4, IL-5 and IL-13 that mediate allergic inflammation.
openaire   +2 more sources

GATA-3 controls self-renewal in stressed HSCs

Nature Immunology, 2013
The transcription factor GATA-3 is expressed in quiescent hematopoietic stem cells (HSCs) with long-term repopulating ability. Stress-mediated activation of HSCs promotes localization of GATA-3 to the nucleus in a manner dependent on the mitogen-activated protein kinase p38α and restricts self-renewal.
Toshimi, Yoshida, Katia, Georgopoulos
openaire   +2 more sources

The Function Role of GATA-3 in Th1 and Th2 Differentiation

Immunologic Research, 2003
GATA-3 plays a central role in regulating Th1 and Th2 cell differentiation. Upon interleukin (IL)-4 binding to its receptor, GATA-3 is induced through the action of Stat6. GATA-3 regulates Th2 cytokine expression not only at the transcription level, such as directly binding to the promoters of the IL-5 and IL-13 gene, but also by the involvement in the
Meixia, Zhou, Wenjun, Ouyang
openaire   +2 more sources

Linking GATA-3 and interleukin-13: implications in asthma

Inflammation Research, 2013
Asthma is one of the serious global health problems and cause of huge mortality and morbidity. It is characterized by persistent airway inflammation, airway hyperresponsiveness, increased IgE levels and mucus hypersecretion. Asthma is mediated by dominant Th2 immune response, causing enhanced expression of Th2 cytokines. These cytokines are responsible
Sheikh, Rayees   +3 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy