Results 31 to 40 of about 46,185 (207)

GATA-3 Stimulates Proliferation of Endometriotic Cells

Ginekologia Polska, 2019
This study aimed to investigate whether there was a correlation between the expression of GATA binding protein 3 (GATA-3) and the proliferation of endometrium cells from women with endometriosis.Endometrial tissue was collected from 20 women with endometriosis (experimental group) and 10 women without endometriosis (control group).
Peng, Chen, Fang, Ren, Dan-Bo, Wang
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Expression of GATA‐3 During Lymphocyte Differentiation and Mouse Embryogenesis [PDF]

Journal of Immunology Research, 1992
The GATA family of C4 zinc‐finger transcription factors has been implicated in tissuespecific gene regulation in birds and mammals. One of the members of this family, GATA‐3, is reportedly expressed specifically in the T‐cell lineage, where it interacts with GATA motifs in the TCR‐αα, TCR‐β/, and TCR‐δ enhancers, thereby controlling the T‐cell ...
Oosterwegel, M.A., Timmerman, J., Leiden, J., Clevers, J.C.   +3 more
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Down-regulated GATA-1 up-regulates interferon regulatory factor 3 in lung adenocarcinoma

Scientific Reports, 2017
Interferon regulatory factor 3 (IRF-3) is widely known for its prompt response against viral infection by activating the interferon system. We previously reported that E2F1, Sp1 and Sp3 regulated transcriptional activity of IRF-3.
Lu-Lu Wang, Zheng-Sen Chen, Wen-Di Zhou, Jin Shu, Xiao-Hua Wang, Rui Jin, Li-Li Zhuang, Mir Alireza Hoda, Hao Zhang, Guo-Ping Zhou   +9 more
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Immunohistoochemical evaluation of GATA-3, pAKT and Ki-67 in triple negative breast carcinoma

Journal of Pathology of Nepal, 2017
Background: Triple-negative breast cancers lack expression of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor -2. These tumors have been known to be clinically aggressive. We evaluate GATA-3, pAKT and Ki-67 expression
Gopi Aryal, Sameer Chhetri Aryal, Yurie Soejima, Victoria Sheckler, Yoshinobu Eishi, Motoji Sawabe   +5 more
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Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease.

PLoS Medicine, 2009
BackgroundGATA-3 plays a critical role in regulating the expression of the cytokines interleukin (IL)-4, IL-5, and IL-13 from T helper-2 (Th2) cells and therefore is a key mediator of allergic diseases. Corticosteroids are highly effective in suppressing
Kittipong Maneechotesuwan, Xin Yao, Kazuhiro Ito, Elen Jazrawi, Omar S Usmani, Ian M Adcock, Peter J Barnes   +6 more
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FoxP3, GATA‐3 and T‐bet expression in elderly asthma [PDF]

Clinical & Experimental Allergy, 2010
Cite this as: S. Vale‐Pereira, A. Todo‐Bom, L. Geraldes, C. Schmidt‐Weber, C. A. Akdis and A. Mota‐Pinto, Clinical & Experimental Allergy, 2011 (41) 490–496.SummaryBackground Asthma is a chronic inflammatory disorder in which Th2, Th1 and suppressive T cells (Tregs) play a role.
Vale-Pereira, S, Todo-Bom, A, Geraldes, L, Schmidt-Weber, Carsten, Akdis, C A, Mota-Pinto, A   +5 more
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Constitutive phosphorylation of GATA-1 at serine²⁶ attenuates the colony-forming activity of erythrocyte-committed progenitors.

PLoS ONE, 2013
We previously reported that IL-3 signaling induces phosphorylation of GATA-1 at the serine²⁶ position, which contributes to IL-3-mediated anti-apoptotic response. Here, we demonstrate that phosphorylation of GATA-1 at serine²⁶ is also transiently induced
Kou-Ray Lin, Chung-Leung Li, Jeffrey Jong-Young Yen, Hsin-Fang Yang-Yen   +3 more
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Intranasal Administration of Lentiviral miR-135a Regulates Mast Cell and Allergen-Induced Inflammation by Targeting GATA-3. [PDF]

PLoS ONE, 2015
Mast cell (MC) degranulation is the foundation of the acute phase of allergic rhinitis (AR). Previously, downregulation of GATA binding protein 3 (GATA-3) was shown to suppress MC activation in an AR mouse model.
Yu-Qin Deng, Ya-Qi Yang, Shui-Bin Wang, Fen Li, Meng-Zhi Liu, Qing-Quan Hua, Ze-Zhang Tao   +6 more
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GATA-3 localization shapes lymphocyte function

Cell Reports
Despite the crucial roles of GATA-3 in lymphocyte biology, little is known about its intracellular distribution and the mechanisms regulating its nuclear import. Single-cell analyses on confocal microscopy images revealed that GATA-3 was enriched in the nucleus of naive and T helper (Th)2 cells, whereas Th1 cells preferentially accumulated it in the ...
Saikali, P., Dzamukova, M., Stehle, C., Nguyen, T., Brunner, T., Baumann, C., Hegazy, A., Kaufmann, S., Romagnani, C., Löhning, M.   +9 more
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Ectopic non-gestational pure choriocarcinoma of the urinary bladder in a young nulliparous female: A diagnostic challenge

Indian Journal of Medical and Paediatric Oncology, 2020
Choriocarcinoma can occur at ectopic extragenital locations such as lungs, mediastinum, retroperitoneum, and even in the brain (nongestational choriocarcinoma).
Rahul Mannan, Sonam Sharma, Saloni Goyal, Tejinder Singh Bhasin   +3 more
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