Results 31 to 40 of about 18,250,723 (243)
GATA-3 and the regulation of the mammary luminal cell fate [PDF]
Current Opinion in Cell Biology, 2008 The GATA family of transcription factors plays essential roles in the specification and maintenance of differentiated cell types. GATA-3 was identified in a microarray screen of the mouse mammary gland as the most highly expressed transcription factor in the mammary epithelium and is expressed exclusively in the luminal epithelial cell population ...
Hosein, Kouros-Mehr +3 more
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Transcription factor GATA‐3 is essential for lens development [PDF]
Developmental Dynamics, 2009 AbstractDuring vertebrate lens development, the anterior, ectoderm‐derived lens vesicle cells differentiate into a monolayer of epithelial cells that retain proliferative potential. Subsequently, they exit the cell cycle and give rise to posterior lens fiber cells that form the lens body.
Maeda, Atsuko +9 more
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Global Analysis of Dynamic Epigenetic Marking and Transcriptional Regulation Underlying T-Cell Lineage Commitment [PDF]
, 2012 T-cell lineage specification and commitment success depends on precise temporal induction of T-lineage specific genes, as well as repression of lineage-inappropriate programs. After entry into the thymus, T-cell progenitors still retain inherited lineage
Zhang, Jingli A.
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Function of Gata-2 in thymic epithelial cells : a transcription factor identified from gene expression analysis of endodermal cells committed to thymic epithelial cell fate [PDF]
, 2010 The thymus structure composes of clear morphological regions. The T-cell precursors enter the thymus in the cortico-medullary junction and migrate through the cortex towards the sub capsular region and back through to the cortex into the medulla.
Na, Kyung-Jae
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Embryonic expression of the human GATA-3 gene
Mechanisms of Development, 1999 The spatial and temporal analysis of GATA-3 expression pattern in the human embryo revealed its expression in new anatomical sites. These include the endoderm of the primitive foregut, pharynx and allantois, the branchial arches and the mesenchymal cells surrounding the stomach and dorsal aorta.
Debacker, Cécile +2 more
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Embryonic expression and cloning of the murine GATA-3 gene [PDF]
Development, 1994 ABSTRACT We describe the embryonic expression pattern as well as the cloning and initial transcriptional regulatory analysis of the murine (m) GATA-3 gene. In situ hybridization shows that mGATA-3 mRNA accumulation is temporally and spatially regulated during early development: although found most abundantly in the placenta prior to 10 ...
K M, George +6 more
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Transcriptional regulation of the human ALDH1A1 promoter by the oncogenic homeoprotein TLX1/HOX11 [PDF]
, 2009 The homeoprotein TLX1, which is essential to spleen organogenesis and oncogenic when aberrantly expressed in immature T cells, functions as a bifunctional transcriptional regulator, being capable of activation or repression depending on cell type and/or ...
Heidari, M. +10 more
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EXPRESSION OF GATA 3 IN EPITHELIAL TUMORS
Pakistan Armed Forces Medical Journal, 2020 Objective: To assess the expression of GATA-3 among epithelial tumors of four organs including invasive mammary carcinoma, prostatic adenocarcinoma, colorectal carcinoma and high grade serous carcinoma of ovary.
Amna Asif +4 more
doaj +2 more sources
Aberrant Gata-3 Expression in Human Pancreatic Cancer [PDF]
Journal of Histochemistry & Cytochemistry, 2006 Gata-3 has been shown to specifically alter its expression patterns in different types of cancers. Recent evidence suggests that an interference of Gata-3 exists in the TGF-β signaling pathway. To determine the role of Gata-3 in pancreatic cancer, pancreatic cancer samples were analyzed in comparison to normal pancreatic tissues.
Antanas, Gulbinas +9 more
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GATA-3 EXPRESSION IN PERIPHERAL BLOOD LYMPHOCYTES OF PATIENTS WITH BRONCHIAL ASTHMA
Медицинская иммунология, 2014 The aim of the study is to establish the features of expression of GATA-3 in peripheral lymphocytes from bronchial asthma patients (BA). Material and methods.
V. N. Mineev +3 more
doaj +1 more source