Results 51 to 60 of about 18,362,222 (202)
A Pooled CRISPR Screen Reveals Genes Critical for Erythroblast Enucleation
American Journal of Hematology, EarlyView.ABSTRACT Terminal erythroid differentiation involves dramatic cellular remodeling that culminates in the expulsion of the nucleus, a process known as enucleation. While enucleation is conserved across mammals and is crucial for the generation of fully functional erythrocytes, the mechanisms governing this process have remained largely unknown, in part ...
Marilou Tetard +7 more
wiley +1 more source
Медицинская иммунология, 2014 . The review article summarizes current information about transcriptional factors Fохр3, GATA- 3, РАХ-5 and their cooperative interactions. Predomination of one of these factors leads to production of corresponding cytokines and appropriate changes in T ...
V. N. Mineev +4 more
doaj +1 more source
Indian Journal of Medical and Paediatric Oncology, 2020 Choriocarcinoma can occur at ectopic extragenital locations such as lungs, mediastinum, retroperitoneum, and even in the brain (nongestational choriocarcinoma).
Rahul Mannan +3 more
doaj +1 more source
TCR-Dependent Translational Control of GATA-3 Enhances Th2 Differentiation
, 2010 The differentiation of CD4+ T cells into the Th2 subset is controlled by the transcription factor GATA-3. GATA-3 is both necessary and sufficient for Th2 differentiation and works through the induction of chromatin remodeling at the Th2 effector cytokine
Kevin D. Cook, Jim Miller
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Anti‐homocitrullinated protein/peptide antibodies are specific to rheumatoid arthritis (RA) and predictive of worse prognosis, suggesting a pathogenic role for autoreactivity to homocitrullinated peptides (HomoCitP). However, T cell responses to HomoCitP remain largely unexplored.
Sofya Ulanova +6 more
wiley +1 more source
Agronomy, 2023 GATA transcription factor is crucial for plant growth and development, physiological metabolism, and environmental response, which has been reported in many plants.
Yuchao Hu +7 more
doaj +1 more source
Developmental Dynamics, EarlyView.Abstract The sea anemone, Nematostella vectensis, has been used as a model organism in developmental biology studies for many years. This estuarine species has the notable capacity to regenerate its full body plan from small pieces throughout life. Nematostella have been described as having a great degree of cellular plasticity.
Patrick A. Lewis +3 more
wiley +1 more source
Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression. [PDF]
PLoS ONE, 2011 Allergic asthma is associated with airway eosinophilia, which is regulated by different T-effector cells. T cells express transcription factors T-bet, GATA-3, RORγt and Foxp3, representing Th1, Th2, Th17 and Treg cells respectively. No study has directly
You Lu +6 more
doaj +1 more source
GATA-3 Dose-Dependent Checkpoints in Early T Cell Commitment [PDF]
, 2014 GATA-3 expression is crucial for T cell development and peaks during commitment to the T cell lineage, midway through the CD4CD8 (double-negative [DN]) stages 1–3.
Butler, Robert R., III +9 more
core
Food Safety and Health, EarlyView.In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso +3 more
wiley +1 more source