Results 71 to 80 of about 18,250,723 (243)
GATA-3 Dose-Dependent Checkpoints in Early T Cell Commitment [PDF]
, 2014 GATA-3 expression is crucial for T cell development and peaks during commitment to the T cell lineage, midway through the CD4CD8 (double-negative [DN]) stages 1–3.
Butler, Robert R., III +9 more
core
Arthritis &Rheumatology, EarlyView.Objective Anti‐homocitrullinated protein/peptide antibodies are specific to rheumatoid arthritis (RA) and predictive of worse prognosis, suggesting a pathogenic role for autoreactivity to homocitrullinated peptides (HomoCitP). However, T cell responses to HomoCitP remain largely unexplored.
Sofya Ulanova +6 more
wiley +1 more source
GATA-3: an unexpected regulator of cell lineage determination in skin [PDF]
Genes & Development, 2003 Multipotent skin stem cells give rise to epidermis and its appendages, including the hair follicle. The Lef-1/Tcf family of Wnt-regulated transcription factors plays a major role in specification of the hair shaft, but little is known about how the equally important hair channel, the inner root sheath (IRS), develops in concert to shape and guide the ...
Charles K, Kaufman +8 more
openaire +2 more sources
GATA-Serpent gene silencing in A. aquasalis.
, 2018 (A) Effect of dsSrp injections on GATA-Serpent and on the housekeeping RP49 gene mRNA expression. (B) Life span of mosquitoes 3–22 days after injections with dsSrp and dsβ-gal (control) maintained on 10% sucrose solution. The survival rates were analyzed
Leonardo B. Koerich (5782397) +9 more
core +1 more source
Developmental Dynamics, EarlyView.Abstract The sea anemone, Nematostella vectensis, has been used as a model organism in developmental biology studies for many years. This estuarine species has the notable capacity to regenerate its full body plan from small pieces throughout life. Nematostella have been described as having a great degree of cellular plasticity.
Patrick A. Lewis +3 more
wiley +1 more source
ScRNA-Seq Analyses Define the Role of GATA3 in iNKT Cell Effector Lineage Differentiation
CellsWhile the transcription factor GATA-3 is well-established for its crucial role in T cell development, its specific influence on invariant natural killer T (iNKT) cells remains relatively unexplored.
Tzong-Shyuan Tai +6 more
doaj +1 more source
The junctional proteins cingulin and paracingulin modulate the expression of tight junction protein genes through GATA-4. [PDF]
PLoS ONE, 2013 The cytoplamic junctional proteins cingulin and paracingulin have been implicated in the regulation of gene expression in different cultured cell models.
Laurent Guillemot +2 more
doaj +1 more source
Cyclic Regulation of T-Bet and GATA-3 in Human Endometrium [PDF]
Reproductive Sciences, 2008 Endometrial cytokine expression is poorly understood. T-Bet and GATA-3 regulate cytokine expression in T-lymphocytes. Previous work has demonstrated expression of T-Bet in human endometrium. Changes in human endometrial T-Bet and GATA-3 mRNA and protein expression during the normal menstrual cycle were characterized.
Danielle, Inman +4 more
openaire +2 more sources
Food Safety and Health, EarlyView.In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso +3 more
wiley +1 more source
GATA-3 locks the door to the B-cell option
Blood, 2013 In this issue of Blood, García-Ojeda et al demonstrate a key mechanism that drives T and B lymphocytes to divergent fates from early in their development.
openaire +5 more sources