Results 61 to 70 of about 18,362,222 (202)

ScRNA-Seq Analyses Define the Role of GATA3 in iNKT Cell Effector Lineage Differentiation

open access: yesCells
While the transcription factor GATA-3 is well-established for its crucial role in T cell development, its specific influence on invariant natural killer T (iNKT) cells remains relatively unexplored.
Tzong-Shyuan Tai   +6 more
doaj   +1 more source

GATA-Serpent gene silencing in A. aquasalis.

open access: yes, 2018
(A) Effect of dsSrp injections on GATA-Serpent and on the housekeeping RP49 gene mRNA expression. (B) Life span of mosquitoes 3–22 days after injections with dsSrp and dsβ-gal (control) maintained on 10% sucrose solution. The survival rates were analyzed
Leonardo B. Koerich (5782397)   +9 more
core   +1 more source

GATA-3 Function in Innate and Adaptive Immunity. [PDF]

open access: yes, 2014
International audience: The zinc-finger transcription factor GATA-3 has received much attention as a master regulator of T helper 2 (Th2) cell differentiation, during which it controls interleukin-4 (IL-4), IL-5, and IL-13 expression. More recently, GATA-
Hendriks, Rudi W.   +12 more
core   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

open access: yesIbrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

The junctional proteins cingulin and paracingulin modulate the expression of tight junction protein genes through GATA-4. [PDF]

open access: yesPLoS ONE, 2013
The cytoplamic junctional proteins cingulin and paracingulin have been implicated in the regulation of gene expression in different cultured cell models.
Laurent Guillemot   +2 more
doaj   +1 more source

The Enteric Nervous System: An Integrative Hub From Development to Systemic Physiology

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Unlike a static hardwired circuit, the ENS continuously remodels its transcriptional programs and synaptic connectivity in response to three ecological forces: microbial metabolites, immune cell signals and enteroendocrine cues. ABSTRACT The enteric nervous system (ENS) constitutes the largest and most functionally autonomous subdivision of the ...
Mario Cuchillo‐Hilario   +3 more
wiley   +1 more source

Gata-binding sites are critical for animal hemisphere-specific gene expression.

open access: yes, 2016
(A) Analysis of a regulatory region of Efna.d. Illustrations on the left depict the constructs. The numbers indicate the relative nucleotide positions from the transcription start site of Efna.d. Mutant Tcf7-binding sites are indicated by X.
Ute Rothbächer (17811)   +5 more
core   +1 more source

Triggering Receptor Expressed on Myeloid Cells‐2 Regulates Innate Lymphoid Cell Levels in Bleomycin‐Induced Pulmonary Fibrosis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Idiopathic pulmonary fibrosis, a pathological change causing poor outcomes, is not reversible despite current antifibrotic therapy. Emerging evidence suggests that innate lymphoid cells (ILCs) mediate lung inflammation and fibrosis after stimulation by endogenous factors.
Hsiao‐Chin Shen   +7 more
wiley   +1 more source

The influence of artesunate on T-bet /GATA-3 equilibrium of peripheral blood in oral lichen planus

open access: yes口腔疾病防治, 2016
Objective To explore influence of artesunate on T-bet /GATA-3 equilibrium of peripheral blood in oral lichen planus.Methods 18 OLP patients were selected,and peripheral blood mononuclear cells (PBMCs) were isolated by density gradient centrifugation. The
LIU Li-fang   +3 more
doaj   +1 more source

The GATA-3 gene is expressed during human kidney embryogenesis [PDF]

open access: yes, 1995
The GATA-3 gene is expressed during human kidney embryogenesis. GATA-3 is a transcription factor involved in the differentiation of T lymphocytes and additionally expressed in several chicken and mouse embryonic tissues.
Catala, Martin   +3 more
core   +1 more source

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