Results 21 to 30 of about 18,250,723 (243)

GATA-3 Suppression by DNAzyme Modulates Interleukin-10 and Liver Injury Markers in db/db Mice [PDF]

Biology
Obesity plays a crucial role in the progression of insulin resistance and type 2 diabetes which are related to inflammation and liver disease. GATA-3 is a transcription factor that is involved in adipogenesis and inflammation.
Layla Al-Mansoori, Asma A. Elashi, Laila Hedaya, Maha Alser, Shamma Almuraikhy, Najeha Anwardeen, Hend Al-Jaber, Suhad Hussain, Hamda A. Al-Naemi, Vijay Govindharajan, Rafif Mahmood Al-Saady, Mohammed Imad Malki, Khaled Naja, Mohamed A. Elrayess   +13 more
doaj   +2 more sources

Expression of T-Bet, Eomesodermin, and GATA-3 Correlates With Distinct Phenotypes and Functional Properties in Porcine γδ T Cells [PDF]

Frontiers in Immunology, 2019
Unlike mice and humans, porcine γδ T cells represent a prominent subset of T cells in blood and secondary lymphatic organs. GATA-3, T-bet and Eomesodermin (Eomes) are transcription factors with crucial functions in T-cell development and functional ...
Irene M. Rodríguez-Gómez, Stephanie C. Talker, Tobias Käser, Maria Stadler, Lisa Reiter, Andrea Ladinig, Jemma V. Milburn, Jemma V. Milburn, Sabine E. Hammer, Kerstin H. Mair, Kerstin H. Mair, Armin Saalmüller, Wilhelm Gerner, Wilhelm Gerner   +13 more
doaj   +2 more sources

Mammary like gland adenoma with GATA-3 expression - a benign vulval tumor with mammary differentiation often misdiagnosed as adenocarcinoma [PDF]

New Indian Journal of OBGYN, 2021
Papillary hidradenoma/ mammary-like gland adenoma (MLGA) is a benign glandular tumor of the vulva. It presents as a mass lesion which often undergoes secondary ulceration and bleeding resembling a malignant tumor.
Deval Parekh, Sunaina Wadhwa, Asima Mukhopadhyay, Angad Singh   +3 more
doaj   +1 more source

Comparison of the expression of GATA-3 protein from the transcription factor family and pathological prognostic parameters in invasive ductal carcinomas of the breast

Turkish Journal of Internal Medicine, 2022
Background GATA binding protein 3 (GATA-3) is one of the six transcription factor family members and is important for glandular development in the breast. Its expression becomes important in breast cancer.
Leymune Parlak, Olcay Kandemir
doaj   +1 more source

Gata-3 and mammary cell fate [PDF]

Breast Cancer Research, 2007
Genomic regulatory networks specify how cellular gene expression responds to external temporal and spatial stimuli, ensuring that correct cell fate decisions are made and the appropriate cell phenotypes are adopted. In mammary epithelial cells, the hierarchy of stem and progenitor cells and the genetically specified program of transcriptional activity ...
Naylor, Matthew J, Ormandy, Christopher J   +1 more
openaire   +2 more sources

Can GATA3 Immunocytochemistry be Utilized as a Reliable Diagnostic Marker for Metastatic Breast Carcinoma in Cytological Materials? A Comparative Study with Mammaglobin and GCDFP-15 Expression [PDF]

Türk Patoloji Dergisi, 2018
Objective: Cytomorphologic differentiation of metastatic breast carcinoma from non breast metastases in cytological materials can be difficult. Current breast immunocytochemical markers have low sensitivities.
Nesreen H. HAFEZ, HebatAllah M. SHAABAN
doaj   +1 more source

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

Modelling Down Syndrome leukaemia using transchromosomic ES cell lines. [PDF]

, 2009
PhDAMKL (acute megakaryoblastic leukaemia) accounts for at least 50% of all cases of acute myeloid leukaemia (AML) associated with Down Syndrome (DS). Every tenth neonate with DS develops Transient Myeloproliferative Disorder (TMD), a self-regressing
De Vita, Serena
core   +4 more sources

GATA‐binding protein 3 and gross cystic disease fluid protein 15 as a potential diagnostic marker for extramammary Paget's disease

Journal of Cutaneous Immunology and Allergy, 2021
Objectives The aim of this study was to evaluate the expression of GCDFP15 and GATA‐binding protein 3 (GATA‐3) in extramammary Paget's disease (EMPD) skin and serum samples and to assess their availability as tumor markers for the diagnosis and ...
Soichiro Kado, Koji Kamiya, Meijuan Jin, Miho Kimura, Md Razib Hossain, Takeo Maekawa, Mayumi Komine, Mamitaro Ohtsuki   +7 more
doaj   +1 more source

FOG-1, a transcriptional regulator within the haematopoietic system [PDF]

, 2013
Friend of GATA-1 (FOG-1) is a member of the friend of GATA (FOG) family of proteins, which consists of large multitype zinc finger cofactors that bind to the amino zinc finger of GATA transcription factors and modulate their activity.
Versavel, Aude
core   +1 more source