Modelling Down Syndrome leukaemia using transchromosomic ES cell lines. [PDF]
, 2009 PhDAMKL (acute megakaryoblastic leukaemia) accounts for at least 50% of all cases of acute myeloid leukaemia (AML) associated with Down Syndrome (DS). Every tenth neonate with DS develops Transient Myeloproliferative Disorder (TMD), a self-regressing
De Vita, Serena
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Journal of Cutaneous Immunology and Allergy, 2021 Objectives The aim of this study was to evaluate the expression of GCDFP15 and GATA‐binding protein 3 (GATA‐3) in extramammary Paget's disease (EMPD) skin and serum samples and to assess their availability as tumor markers for the diagnosis and ...
Soichiro Kado +7 more
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FOG-1, a transcriptional regulator within the haematopoietic system [PDF]
, 2013 Friend of GATA-1 (FOG-1) is a member of the friend of GATA (FOG) family of proteins, which consists of large multitype zinc finger cofactors that bind to the amino zinc finger of GATA transcription factors and modulate their activity.
Versavel, Aude
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Global Analysis of Dynamic Epigenetic Marking and Transcriptional Regulation Underlying T-Cell Lineage Commitment [PDF]
, 2012 T-cell lineage specification and commitment success depends on precise temporal induction of T-lineage specific genes, as well as repression of lineage-inappropriate programs. After entry into the thymus, T-cell progenitors still retain inherited lineage
Zhang, Jingli A.
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Function of Gata-2 in thymic epithelial cells : a transcription factor identified from gene expression analysis of endodermal cells committed to thymic epithelial cell fate [PDF]
, 2010 The thymus structure composes of clear morphological regions. The T-cell precursors enter the thymus in the cortico-medullary junction and migrate through the cortex towards the sub capsular region and back through to the cortex into the medulla.
Na, Kyung-Jae
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EXPRESSION OF GATA 3 IN EPITHELIAL TUMORS
Pakistan Armed Forces Medical Journal, 2020 Objective: To assess the expression of GATA-3 among epithelial tumors of four organs including invasive mammary carcinoma, prostatic adenocarcinoma, colorectal carcinoma and high grade serous carcinoma of ovary.
Amna Asif +4 more
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Transcriptional regulation of the human ALDH1A1 promoter by the oncogenic homeoprotein TLX1/HOX11 [PDF]
, 2009 The homeoprotein TLX1, which is essential to spleen organogenesis and oncogenic when aberrantly expressed in immature T cells, functions as a bifunctional transcriptional regulator, being capable of activation or repression depending on cell type and/or ...
Heidari, M. +10 more
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GATA-3 Stimulates Proliferation of Endometriotic Cells [PDF]
, 2019 Objectives: This study aimed to investigate whether there was a correlation between the expression of GATA binding protein 3 (GATA-3) and the proliferation of endometrium cells from women with endometriosis.
Ren, Fang; Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China +2 more
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GATA-3 EXPRESSION IN PERIPHERAL BLOOD LYMPHOCYTES OF PATIENTS WITH BRONCHIAL ASTHMA
Медицинская иммунология, 2014 The aim of the study is to establish the features of expression of GATA-3 in peripheral lymphocytes from bronchial asthma patients (BA). Material and methods.
V. N. Mineev +3 more
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Immunohistoochemical evaluation of GATA-3, pAKT and Ki-67 in triple negative breast carcinoma
Journal of Pathology of Nepal, 2017 Background: Triple-negative breast cancers lack expression of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor -2. These tumors have been known to be clinically aggressive. We evaluate GATA-3, pAKT and Ki-67 expression
Gopi Aryal +5 more
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