Results 91 to 100 of about 6,168 (196)

Breast Skin Lesions in a 79‐Year‐Old Woman

JEADV Clinical Practice, EarlyView.
Javier Lorenz‐Dolz, Fátima Mayo‐Martínez, Andrea Díez Santandreu, Onofre Sanmartín Jiménez, Ruggero Moro   +4 more
wiley   +1 more source

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam, M Figura, J Heyer, S Lieber, M Huber, KL Loveland, HC Schuppe, Daniela Fietz   +7 more
wiley   +1 more source

GATA3 (GATA binding protein 3) [PDF]

, 2012
Review on GATA3 (GATA binding protein 3), with data on DNA, on the protein encoded, and where the gene is ...
Bouchard, M, Tremblay, M
core   +1 more source

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair follicles [PDF]

, 2007
The transcription factor Gata3 is crucially involved in epidermis and hair follicle differentiation. Yet, little is known about how Gata3 co-ordinates stem cell lineage determination in skin, what pathways are involved and how Gata3 differentially ...
Kurek, Dorota, Doorninck, Hikke, van der Wees, J (Jacqueline), Garinis, G.A. (George), J. Hikke van Doorninck, Frank G. Grosveld, Kurek, D. (Dorota), Doorninck, J.H. (Hikke) van, Jacqueline van der Wees, Dorota Kurek, George A. Garinis, Grosveld, Frank, Wees, J. (Jacqueline) van der, Garinis, G, Grosveld, F.G. (Frank)   +14 more
core   +1 more source

A luminal non‐coding RNA‐based genomic classifier confirms favourable outcomes in patients with clinically organ‐confined bladder cancer treated with radical cystectomy

BJU International, Volume 135, Issue 4, Page 648-656, April 2025.
Objective To further evaluate a genomic classifier (GC) in a cohort of patients undergoing radical cystectomy (RC), as long non‐coding RNA (lncRNA)‐based genomic profiling has suggested utility in identifying a distinct tumour subgroup corresponding to a favourable prognosis in patients with bladder cancer.
Joep J. de Jong, James A. Proudfoot, Siamak Daneshmand, Robert S. Svatek, Vikram Narayan, Ewan A. Gibb, Elai Davicioni, Shreyas Joshi, Aaron Dahmen, Roger Li, Brant A. Inman, Paras Shah, Iftach Chaplin, Jonathan Wright, Yair Lotan   +14 more
wiley   +1 more source

Supplementary Material for: Expression Pattern of Smad4/GATA3 as a Predictor of Survival in Invasive Ductal Carcinoma of the Breast

, 2017
Background: Smad4 and GATA3 proteins are known prognostic markers in various cancers. Smad4 is a mediator linked to both tumour suppression and progression. GATA3 is a regulator of development and morphogenesis of the mammary gland.
Min K.-W. (3820243), Park C.H. (3834895), Oh S. (3834904), Kim K. (3834916), Kim E.-K. (3820225), Kim D.H. (2862686), Park Y.L. (3834910), Sohn J.H. (3834922), Chae S.W. (3834913), Choi S.H. (3199221), Kwon M.J. (3834901), Kim Y. (3112977), Kim D.-H. (3820237), Do I.-G. (3834919), Pyo J.-S. (3834892), Yang J.-H. (3834886), Lee S.-J. (2861408), Do S.-I. (3834898), Lee H.J. (3834889), Oh Y.H. (3834907)   +19 more
core   +1 more source

Long Non‐Coding RNA, Like NEAT1 and MALAT1, in Asthma: Mechanisms and Therapeutic Potential

Clinical &Experimental Allergy, EarlyView.
Long non‐coding RNA, like NEAT1 and MALAT1, is emerging as a regulator of asthma‐related inflammation, airway remodelling, viral responses and cell death pathways, and are promising targets for future therapeutics. ABSTRACT Asthma affects millions worldwide. Long non‐coding RNA (lncRNA) are emerging as important factors in the pathophysiology of asthma
Ashlyn Poole, Ingrid Laing, Ryan Mead‐Hunter, Peter Le Souef, Guicheng Zhang   +4 more
wiley   +1 more source

Additional file 1 of GATA3 functions downstream of BRCA1 to promote DNA damage repair and suppress dedifferentiation in breast cancer

Additional file 1: Fig. S1. Analysis of cell proliferation in primary mammary tumors. Representative mammary tumors were analyzed by IHC with an antibody against Ki-67. Two independent mammary tumors derived from p18-/-, p18-/-;Gata3+/- and p18-/-;Brca1+/
Bin Peng (31749), Li Fu (85791), Hongquan Zhang (61781), Xin-Hai Pei (10021895), Feng Bai (336697), Wei-Guo Zhu (1388703), Bin Wang (30851), Xiong Liu (43564), Xingzhi Xu (3387002), Xuejie Wang (5955284)   +9 more
core   +1 more source

Ectopic ureteric budding in Gata3^ND−/− embryos.

, 2013
(A–F) Dissected urogenital systems of control (HoxB7-Cre; Gata3flox/+; Rosa26STOPlacZ/+) and Gata3ND−/− (HoxB7-Cre; Gata3flox/flox; Rosa26STOPlacZ/+) embryos were stained for β-Galactosidase activity at the indicated embryonic stages.
Sami Kamel Boualia (375352), Maxime Bouchard (216093), Abdallah Souabni (375354), Calli Merkel (375356), David Grote (375350), Xuan Chi (136651), Frank Costantini (58908), Thomas Carroll (375358)   +7 more
core   +1 more source