Results 71 to 80 of about 6,168 (196)

GATA Binding Protein 3 Is a Direct Target of Kruppel-Like Transcription Factor 7 and Inhibits Chicken Adipogenesis

Frontiers in Physiology, 2020
Kruppel-like transcription factor 7 (KLF7) is a negative regulator of adipogenesis, however, its precise mechanism is poorly understood. Our previous KLF7 ChIP-seq analysis showed that one of the KLF7 binding peaks was present upstream of GATA binding ...
Yingning Sun, Yingning Sun, Yingning Sun, Yingning Sun, Zhao Jin, Xinyang Zhang, Xinyang Zhang, Xinyang Zhang, Tingting Cui, Tingting Cui, Tingting Cui, Tingting Cui, Wenjian Zhang, Wenjian Zhang, Wenjian Zhang, Shuli Shao, Hui Li, Hui Li, Hui Li, Ning Wang, Ning Wang, Ning Wang   +21 more
doaj   +1 more source

Triggering Receptor Expressed on Myeloid Cells‐2 Regulates Innate Lymphoid Cell Levels in Bleomycin‐Induced Pulmonary Fibrosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Idiopathic pulmonary fibrosis, a pathological change causing poor outcomes, is not reversible despite current antifibrotic therapy. Emerging evidence suggests that innate lymphoid cells (ILCs) mediate lung inflammation and fibrosis after stimulation by endogenous factors.
Hsiao‐Chin Shen, Nien‐Jung Chen, Chuan‐Yen Sun, Wen‐Kuang Yu, Vincent Yi‐Fong Su, Wan‐Ling Yang, Wei‐Chih Chen, Kuang‐Yao Yang   +7 more
wiley   +1 more source

Genome-wide characterization of Gata3 binding sites in ChIP-seq.

, 2014
(A) Top binding motif identified by MEME-ChIP. (B) Conservation plot of Gata3 binding sites in vertebrate species. (C) The genome-wide distribution of Gata3-binding sites.
Jinhua Liu (189844), Gang Wei (372644), Haifang Wang (67779), Jun Yan (28467), Juan Li (146180), Xuelong Wang (104761)   +5 more
core   +1 more source

GATA3 maintains the quiescent state of cochlear supporting cells by regulating p27kip1

Scientific Reports, 2021
Haplo-insufficiency of the GATA3 gene causes hypoparathyroidism, sensorineural hearing loss, and renal disease (HDR) syndrome. Previous studies have shown that Gata3 is required for the development of the prosensory domain and spiral ganglion neurons ...
Jiadong Xu, Dongliang Yu, Xuhui Dong, Xiaoling Xie, Mei Xu, Luming Guo, Liang Huang, Qi Tang, Lin Gan   +8 more
doaj   +1 more source

Mechanism of RNA‐Binding Protein ELAVL1 in Promoting Th2 Cell Differentiation Through Stabilizing CPA3 mRNA in Allergic Rhinitis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to elucidate the role of the RNA‐binding protein embryonic lethality abnormal vision‐like protein 1 (ELAVL1) in the pathogenesis of allergic rhinitis (AR), specifically by investigating its potential to promote T helper 2 (Th2) cell differentiation by regulating the stability of carboxypeptidase A3 (CPA3) mRNA.
Meng‐Ya Liu, Hong‐Bing Yao, Cheng Chen   +2 more
wiley   +1 more source

Summary of Gata3 function in progenitor cell state maintenance in the nephric duct.

, 2013
(A) Genetic regulation experiments with Gata3, β-catenin and Ret mutant embryos identify a cascade whereby Gata3 acts downstream of the β-catenin developmental program to independently maintain Ret expression and to prevent premature differentiation of ...
Sami Kamel Boualia (375352), Maxime Bouchard (216093), Abdallah Souabni (375354), Calli Merkel (375356), David Grote (375350), Xuan Chi (136651), Frank Costantini (58908), Thomas Carroll (375358)   +7 more
core   +1 more source

Barakat Syndrome in a Child: An Uncommon Cause of Hypocalcemic Tetany – A Case Report with Review of Literature

Indian Pediatrics Case Reports
Background: Barakat syndrome is a rare autosomal dominant disorder caused by mutations in the GATA3 gene, manifesting with a combination of hypoparathyroidism, sensorineural deafness, and renal dysplasia.
Subin Sabu, Vivek Dewan, Bharti Dhankhar, Vinay Kumar Mishra   +3 more
doaj   +1 more source

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

Phytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit, Aylin Bülbül, Betul Kocaadam‐Bozkurt, Osman Bozkurt, Duygu Ağagündüz, Raffaele Capasso   +5 more
wiley   +1 more source

GATA3 Immunohistochemical Staining in Classical Hodgkin Lymphoma and Its Diagnostic Utility in Differential Diagnosis

Turkish Journal of Hematology
Objective: Classical Hodgkin lymphoma (CHL) is a common lymphoid neoplasm with a wide range of differential diagnoses. Although it has a specific immunophenotype, aberrant expression of antigens can cause problems at its diagnosis.
Ali Yılmaz Altay, Begüm Yeni, Gulcin Yegen   +2 more
doaj   +1 more source

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

Phytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia, Kaiyi Wu, Jiaying Qi, Nana Huang, Yusheng Liu, Xiumei Gao, Rong Sun   +6 more
wiley   +1 more source