Results 61 to 70 of about 14,917,701 (196)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

GC-MS analysis of aphid cornicle emissions.

open access: yes, 2018
GC-MS chromatogram of trans-β-farnesene collected from aphid with intact siphunculi (a). GC-MS chromatogram of trans-β-farnesene collected from razor treated siphunculi (b). GC-MS chromatogram of trans-β-farnesene collected from laser treated siphunculi (
Nabil Killiny (284104)   +4 more
core   +1 more source

Volatolomics-assisted characterization of the key odorants in green off-flavor black tea and their dynamic changes during processing

open access: yesFood Chemistry: X
Aroma plays a pivotal role in the quality of black tea. However, the acceptability of black tea is greatly limited by the green off-flavor (GOF) resulting from the inappropriate processing control.
Yanqin Yang   +6 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

GC-supplementation partially rescues fitness of cells with GC-rich plasmids.

open access: yes, 2019
Eight pairwise cocultures of cells harbouring AT-rich and GC-rich pJet plasmids were co-inoculated (1:1 ratio) and serially propagated on a daily basis. Strains were supplied with AT or GC deoxyribonucleosides (100 μM per nucleoside).
Martin Kaltenpoth (82326)   +3 more
core   +1 more source

Enzymatic synthesis of novel pyrrole esters and their thermal stability

open access: yesBMC Chemistry, 2023
In the present work a simple enzymatic approach (Novozym 435) for transesterification to synthesize pyrrole esters was reported. To generate the best reaction conditions, which resulted in the optimum yield of 92%, the effects of lipase type, solvent ...
Jingyi Hu   +6 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

GC-Net evaluation scripts

open access: yes, 2023
This repository contains the scripts used to evaluate the GC-Net L1 dataset. Contributions from: N. Karlsson, J. E. Box, P. Wright. 1) Evaluation against the last files distributed by K.
Baptiste Vandecrux
core   +1 more source

GC-MS, GC-O and OAV analyses of key aroma compounds in Jiaozi Steamed Bread

open access: yesGrain & Oil Science and Technology, 2020
Jiaozi Steamed Bread (JSB) has a unique aroma as a traditional staple food in China. The volatile compounds in JSB were extracted by simultaneous distillation and extraction (SDE) and headspace solid-phase microextraction (HS-SPME).
Yuanhui Wang   +8 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

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