Inducible Nitric Oxide Synthase (iNOS) Mediates Vascular Endothelial Cell Apoptosis in Grass Carp Reovirus (GCRV)-Induced Hemorrhage [PDF]
Hemorrhage is one of the most obvious pathological phenomena in grass carp reovirus (GCRV) infection. The etiology of GCRV-induced hemorrhage is unclear.
Bo Liang, Jianguo Su
core +1 more source
Signatures of dysbiosis in fish microbiomes in the context of aquaculture
Fish gut microbiome is highly susceptible to salinity changes and antimicrobial treatments, whereas external microbiomes seem to be more susceptible to disease and variations in temperature. Treatments with tetracyclines and florfenicol, as well as bacterial diseases, prompt severe dysbiosis, whereas quinolones, disinfectants and parasitic diseases ...
Raquel Xavier +2 more
wiley +1 more source
Grass Carp Prx 3 Elevates Host Antioxidant Activity and Induces Autophagy to Inhibit Grass Carp Reovirus (GCRV) Replication [PDF]
Peroxiredoxins are a family of antioxidant proteins that protect cells from oxidative damage caused by reactive oxygen species (ROS). Herein, the peroxiredoxin 3 gene from grass carp (Ctenopharyngodon idellus), named CiPrx3, was cloned and analyzed.
Yang, Cheng +19 more
core +1 more source
Cloning of six serpin genes and their responses to GCRV infection in grass carp (Ctenopharyngodon idella) [PDF]
Grass carp, an economically important aquaculture fish, is very sensitive to Grass Carp Reovirus (GCRV). Haemorrhagic disease caused by GCRV infection can cause large-scale death of first-year grass carp, thereby severely restricting the intensive ...
Huang, Rong +19 more
core +1 more source
Contamination by dexamethasone (DEX) in aquatic environments is expected to rise significantly as it is used in the treatment of inflammation, allergies, and autoimmune disorders, especially COVID-19. However, the underlying effects and mechanisms of DEX
Siyao Zheng +3 more
doaj +1 more source
Molecular cloning, functional characterization and expression analysis of P65 subunit in response to GCRV infection in rare minnow (Gobiocypris rarus) [PDF]
P65, the all-important subunit of the transcription factor NF-kappa B, plays an important role in the regulation of immune response. In this study, the cDNA of P65 subunit of rare minnow Gobiocypris rarus (GrP65) was cloned, and its expression patterns ...
Lin, Yusheng +4 more
core +1 more source
Protective roles of grass carp Ctenopharyngodon idella Mx isoforms against grass carp reovirus.
BackgroundMyxovirus resistance (Mx) proteins are crucial effectors of the innate antiviral response against a wide range of viruses, mediated by the type I interferon (IFN-I) signaling pathway.
Limin Peng +3 more
doaj +1 more source
The type II Grass Carp Reovirus (GCRV-II) causes severe hemorrhagic disease with high mortality in economically important fish species. However, existing cell culture systems exhibits neither efficient viral replication nor observable cytopathic effects.
Wenji Huang, Sijia Wan, Ling Shao
doaj +1 more source
Additional file 2: Table S2. of Prediction of GCRV virus-host protein interactome based on structural motif-domain interactions [PDF]
Information for predicted motifs information of proteins in GCRV GD108 based on iELM database.
Yaping Wang (289641) +2 more
core +1 more source
Grass carp hemorrhagic disease is caused by the grass carp reovirus (GCRV). The disease spreads rapidly and has a high fatality rate, which seriously affects grass carp culture. Moreover, the molecular mechanisms underlying grass carp hemorrhagic disease
Ziquan Yang +5 more
doaj +1 more source

