Results 91 to 100 of about 909 (176)

Antiviral activities of three grass carp Mx genes against GCRV in transgenic cells.

, 2013
Stable transgenic cells were cultured in 96-well plate for 24 h at 28°C. Monolayer cells were infected with GCRV in duplicate at the indicated densities.
Chunrong Yang (294274), Jianguo Su (294275), Limin Peng (294273)   +2 more
core   +1 more source

Different responses in one-year-old and three-year-old grass carp reveal the mechanism of age restriction of GCRV infection

, 2019
Grass carp is an important fish species in Chinese aquaculture, and can be afflicted by a hemorrhagic disease caused by the grass carp reovirus (GCRV). Interestingly, the affects of GCRV infection of grass carp are age-restricted, meaning that one-year ...
Huang, Rong, Wang, Yaping, Wang, Yumeng, Chen, Geng, Zhu, Zuoyan, Liao, Lanjie, He, Libo, Xiong, Lv   +7 more
core   +2 more sources

Protective roles of grass carp Ctenopharyngodon idella Mx isoforms against grass carp reovirus.

PLoS ONE, 2012
BackgroundMyxovirus resistance (Mx) proteins are crucial effectors of the innate antiviral response against a wide range of viruses, mediated by the type I interferon (IFN-I) signaling pathway.
Limin Peng, Chunrong Yang, Jianguo Su, Jianguo Su   +3 more
doaj   +1 more source

Grass Carp Reovirus (GCRV) Giving Its All to Suppress IFN Production by Countering MAVS Signaling Transduction

, 2020
Viruses typically target host RIG-I-like receptors (RLRs), a group of key factors involved in interferon (IFN) production, to enhance viral infection.
Zhang, Yong-An, Zhou, Yu, Li, Shun, Jiang, Jing-Yu, Chen, Dan-Dan, Zhou, Xiao-Yu, Zhang, Can, Lu, Long-Feng, Li, Zhuo-Cong   +8 more
core   +1 more source

Inducible Nitric Oxide Synthase (iNOS) Mediates Vascular Endothelial Cell Apoptosis in Grass Carp Reovirus (GCRV)-Induced Hemorrhage

, 2019
Hemorrhage is one of the most obvious pathological phenomena in grass carp reovirus (GCRV) infection. The etiology of GCRV-induced hemorrhage is unclear.
Bo Liang, Jianguo Su
core   +1 more source

Grass Carp Prx 3 Elevates Host Antioxidant Activity and Induces Autophagy to Inhibit Grass Carp Reovirus (GCRV) Replication

, 2022
Peroxiredoxins are a family of antioxidant proteins that protect cells from oxidative damage caused by reactive oxygen species (ROS). Herein, the peroxiredoxin 3 gene from grass carp (Ctenopharyngodon idellus), named CiPrx3, was cloned and analyzed.
Yang, Cheng, Zuoyan Zhu, Wang, Hanyue, Liao, Lanjie, Libo He, Xinyu Liang, Cheng Yang, Pengfei Chu, Lanjie Liao, Li, Yongming, Chu, Pengfei, Yongming Li, Hanyue Wang, Wang, Yaping, Yaping Wang, Wang, Qian, Zhu, Zuoyan, Liang, Xinyu, He, Libo, Qian Wang   +19 more
core   +1 more source

Establishment and characterization of a Gobiocypris rarus cell line for studying type II grass carp reovirus infection

Aquaculture Reports
The type II Grass Carp Reovirus (GCRV-II) causes severe hemorrhagic disease with high mortality in economically important fish species. However, existing cell culture systems exhibits neither efficient viral replication nor observable cytopathic effects.
Wenji Huang, Sijia Wan, Ling Shao
doaj   +1 more source

Large-scale SNP screenings identify markers linked with GCRV resistant traits through transcriptomes of individuals and cell lines in Ctenopharyngodon idella

Scientific Reports, 2017
Grass carp (Ctenopharyngodon idella) is an important economic species in freshwater aquaculture and its industry has been confined due to variety degeneration and frequent diseases. Marker-assisted selection is a feasible method for selective breeding of
Zhiwei Liao, Quanyuan Wan, Xueying Shang, Jianguo Su   +3 more
doaj   +1 more source

Comparative Analysis of mRNA, microRNA of Transcriptome, and Proteomics on CIK Cells Responses to GCRV and Aeromonas hydrophila [PDF]

Int J Mol Sci
Grass Carp Reovirus (GCRV) and Aeromonas hydrophila (Ah) are the causative agents of haemorrhagic disease in grass carp. This study aimed to investigate the molecular mechanisms and immune responses at the miRNA, mRNA, and protein levels in grass carp ...
Li X, Lin Y, Li W, Cheng Y, Zhang J, Qiu J, Fu Y.   +6 more
europepmc   +2 more sources

Molecular cloning, functional characterization and expression analysis of P65 subunit in response to GCRV infection in rare minnow (Gobiocypris rarus)

, 2020
P65, the all-important subunit of the transcription factor NF-kappa B, plays an important role in the regulation of immune response. In this study, the cDNA of P65 subunit of rare minnow Gobiocypris rarus (GrP65) was cloned, and its expression patterns ...
Lin, Yusheng, Zhang, Chuang, Wang, Bing, Cao, Hong, Zhou, Man   +4 more
core   +1 more source