Results 91 to 100 of about 954 (183)

The shared immunometabolic responses between dexamethasone-induced hepatobiliary syndrome and GCRV II-caused hemorrhagic disease reveal the pivotal role of autophagy and Hsp90 activity in metabolic and infectious diseases

Water Biology and Security
Contamination by dexamethasone (DEX) in aquatic environments is expected to rise significantly as it is used in the treatment of inflammation, allergies, and autoimmune disorders, especially COVID-19. However, the underlying effects and mechanisms of DEX
Siyao Zheng, Minhui Tao, Xiaoman Wu, Mingxian Chang   +3 more
doaj   +1 more source

IL6-STAT3-HSP90 signaling axis mediates temperature dependency of GCRV infection.

, 2023
(A) CIK cells transfected with different doses of STAT3-C plasmids were prepared to quantify the relative expression of IL6, IL1β, and TNF-α by RT-PCR analysis.
Rui Song (331963), Xiaodong Wang (66801), Hongquan Wang (6086327), Wenzhi Liu (3997184), Zhao Lv (3122814), Qiushi Zhang (3812230), Chunhua Ding (832221), Liang Hu (202392), Junhua Li (125998), Shuting Xiong (630639), Tiaoyi Xiao (9162782), Yong-An Zhang (829491), Guoli Hou (11736683), Chun Li (57810)   +13 more
core   +1 more source

Functional Identification of Complement Factor D and Analysis of Its Expression during GCRV Infection in Grass Carp (Ctenopharyngodon idella)

, 2021
Complement factor D (Df) is a serine protease well known for activating the alternative pathway (AP) in mammals by promoting the cleavage of complement component 3 (C3), thus becoming involved in innate defense.
Baohong Xu, Chunhua Ding, Tiaoyi Xiao, Beibei Qin, Zhao Lv, Hongquan Wang   +5 more
core   +1 more source

Antiviral activities of three grass carp Mx genes against GCRV in transgenic cells.

, 2013
Stable transgenic cells were cultured in 96-well plate for 24 h at 28°C. Monolayer cells were infected with GCRV in duplicate at the indicated densities.
Chunrong Yang (294274), Jianguo Su (294275), Limin Peng (294273)   +2 more
core   +1 more source

Protective roles of grass carp Ctenopharyngodon idella Mx isoforms against grass carp reovirus.

PLoS ONE, 2012
BackgroundMyxovirus resistance (Mx) proteins are crucial effectors of the innate antiviral response against a wide range of viruses, mediated by the type I interferon (IFN-I) signaling pathway.
Limin Peng, Chunrong Yang, Jianguo Su, Jianguo Su   +3 more
doaj   +1 more source

Different responses in one-year-old and three-year-old grass carp reveal the mechanism of age restriction of GCRV infection

, 2019
Grass carp is an important fish species in Chinese aquaculture, and can be afflicted by a hemorrhagic disease caused by the grass carp reovirus (GCRV). Interestingly, the affects of GCRV infection of grass carp are age-restricted, meaning that one-year ...
Huang, Rong, Wang, Yaping, Wang, Yumeng, Chen, Geng, Zhu, Zuoyan, Liao, Lanjie, He, Libo, Xiong, Lv   +7 more
core   +2 more sources

Grass Carp Reovirus (GCRV) Giving Its All to Suppress IFN Production by Countering MAVS Signaling Transduction

, 2020
Viruses typically target host RIG-I-like receptors (RLRs), a group of key factors involved in interferon (IFN) production, to enhance viral infection.
Zhang, Yong-An, Zhou, Yu, Li, Shun, Jiang, Jing-Yu, Chen, Dan-Dan, Zhou, Xiao-Yu, Zhang, Can, Lu, Long-Feng, Li, Zhuo-Cong   +8 more
core   +1 more source

Inducible Nitric Oxide Synthase (iNOS) Mediates Vascular Endothelial Cell Apoptosis in Grass Carp Reovirus (GCRV)-Induced Hemorrhage

, 2019
Hemorrhage is one of the most obvious pathological phenomena in grass carp reovirus (GCRV) infection. The etiology of GCRV-induced hemorrhage is unclear.
Bo Liang, Jianguo Su
core   +1 more source

Establishment and characterization of a Gobiocypris rarus cell line for studying type II grass carp reovirus infection

Aquaculture Reports
The type II Grass Carp Reovirus (GCRV-II) causes severe hemorrhagic disease with high mortality in economically important fish species. However, existing cell culture systems exhibits neither efficient viral replication nor observable cytopathic effects.
Wenji Huang, Sijia Wan, Ling Shao
doaj   +1 more source

Grass Carp Reovirus ( GCRV ): Biology, Immune Responses and Control Strategies

As the world's population grows, aquaculture is becoming a rapidly growing source of protein. Grass carp ( Ctenopharyngodon idella ) is one of the most important ...
Xiao‐Qin Xia, Bin Gui, Wanting Zhang, Mijuan Shi, Lei Zhang, Zhen Xu, Libo He, Fahim Ullah Khan, Lanjie Liao, Zohaib Noor, Yongming Li, Waqar Younas, Yingyin Cheng, Yaping Wang, Rong Huang, Hong Yang   +15 more
core   +1 more source