Results 31 to 40 of about 38,330 (231)
PeerJ, 2019 Melanoma is a global concern and accounts for the major mortality of skin cancers. Herpes simplex virus thymidine kinase gene with ganciclovir (HSV-TK/GCV) is a promising gene therapy for melanoma.
Hong Li +10 more
semanticscholar +1 more source
Lack of Emergence of Cytomegalovirus UL97 Mutations Conferring Ganciclovir (GCV) Resistance following Preemptive GCV Therapy in Allogeneic Stem Cell Transplant Recipients [PDF]
Antimicrobial Agents and Chemotherapy, 2001 ABSTRACT Fifty allogeneic stem cell transplant recipients were enrolled in a prospective cytomegalovirus pp65 antigenemia-guided preemptive therapy trial. Among these, 10 of 34 patients who received ganciclovir exhibited sustained and/or recurrent antigenemia despite treatment.
C, Gilbert +6 more
openaire +2 more sources
Genetic variability and correlation analysis of rice (Oryza sativa L.) inbred lines based on agro-morphological traits [PDF]
, 2016 In order to evaluate genetic variability of agro-morphological traits and also determine the correlation between grain yield with its components in rice lines, 17 recombinants inbred lines, their parents and a check variety were grown in research station
Audebert, Alain +4 more
core +1 more source
International Journal of Oncology, 2018 The ability of herpes simplex virus thymidine kinase/ganciclovir (HSV-TK/GCV) systems to kill tumor cells is partially dependent on the integrity of gap junction intercellular communication (GJIC) of targeted tumor cells.
Dianying Zhang +9 more
semanticscholar +1 more source
Oncology Report, 2018 Retinoblastoma is an severe ophthalmic disease and the most common type intraocular malignant tumor, particularly in infants. Currently, few drugs and therapies are available.
Q. Yi +6 more
semanticscholar +1 more source
Synergistic effect of resveratrol and HSV-TK/GCV therapy on murine hepatoma cells
Cancer Biology & Therapy, 2018 Despite its low transfer efficiency, suicide gene therapy with HSV-TK is known for its bystander killing effect. The connexin-based gap junction is believed to mediate the bystander effect.
Jianyong Xiao +10 more
semanticscholar +1 more source
Molecules, 2021 In the area of gene-directed enzyme prodrug therapy (GDEPT), using herpes simplex virus thymidine kinase (HSV-tk) paired with prodrug ganciclovir (GCV) for cancer treatment has been extensively studied. It is a process involved with two steps whereby the
Alicia J. Sawdon +4 more
doaj +1 more source
Perbandingan Gcv Dan Ubr Dalam Regresi Nonparametrik Multivariabel
Jurnal Matematika, 2021 Analisis regresi merupakan alat dalam statistika dan sering dipakai untuk mengintepretasikan sebab akibat antara satu/beberapa variabel prediktor terhadap satu variabel respon. Spline truncated merupakan pendekatan model regresi nonparametrik yang popular dan sering digunakan.
Luh Putu Safitri Pratiwi +2 more
openaire +2 more sources
Investigating the functionality of an OCT4-short response element in human induced pluripotent stem cells. [PDF]
, 2016 Pluripotent stem cells offer great therapeutic promise for personalized treatment platforms for numerous injuries, disorders, and diseases. Octamer-binding transcription factor 4 (OCT4) is a key regulatory gene maintaining pluripotency and self-renewal ...
Awe, Jason P +9 more
core +3 more sources
Functional principal components analysis via penalized rank one approximation [PDF]
, 2008 Two existing approaches to functional principal components analysis (FPCA) are due to Rice and Silverman (1991) and Silverman (1996), both based on maximizing variance but introducing penalization in different ways.
Buja, Andreas +2 more
core +5 more sources