Results 51 to 60 of about 25,935 (265)
Overall review of curative impact and barriers of CAR-T cells in osteosarcoma
EXCLI Journal : Experimental and Clinical SciencesOsteosarcoma (OS) is a rare form of cancer and primary bone malignancy in children and adolescents. Current therapies include surgery, chemotherapy, and amputation.
Guilin Li, Hong Wang, Vafa Meftahpour
doaj +1 more source
Imaging Pauli repulsion in scanning tunneling microscopy [PDF]
, 2010 A scanning tunneling microscope (STM) has been equipped with a nanoscale force sensor and signal transducer composed of a single D2 molecule that is confined in the STM junction.
Kleimann, C. +5 more
core +2 more sources
Dynamical CP Violation and Flavour-Changing Processes [PDF]
, 2001 We investigate the phenomenological constraints on a model where, besides the standard model Higgs sector, there is an effective new strong interaction acting on the third generation of quarks and characterized by a $\theta$-like term. This $\theta$ term
Abashian +32 more
core +2 more sources
Cancer Research, 2005 AbstractThe GD2 ganglioside expressed on neuroectodermally derived tumors, including neuroblastoma and melanoma, is weakly immunogenic in tumor-bearing patients and induces predominantly immunoglobulin (Ig)-M antibody responses in the immunized host. Here, we investigated whether interconversion of GD2 into a peptide mimetic form would induce GD2 cross-
Bolesta, Elizabeth +12 more
openaire +3 more sources
Preclinical analysis of radiolabeled anti‐GD2 immunoglobulin G [PDF]
Cancer, 1997 Unlabeled murine monoclonal anti-GD2 immunoglobulin (Ig)G (14G2a) reactive with nervous system diganglioside and neuroblastoma, melanoma, and small cell lung carcinoma produces tumor regression. However, serious acute abdominal pain, paresthesia, hypotension and hypertension, syndrome of inappropriate secretion of antidiuretic hormone (SIADH), and ...
F J, Vriesendorp +6 more
openaire +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Interactions between Germ Cells and Extracellular Matrix Glycoproteins during Migration and Gonad Assembly in the Mouse Embryo [PDF]
, 1997 Cells are known to bind to individual extracellular matrix glycoproteins in a complex and poorly understood way. Overall strength of adhesion is thought to be mediated by a combinatorial mechanism, involving adhesion of a cell to a variety of binding ...
Alvarez-Buylla +22 more
core +5 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi +5 more
wiley +1 more source
Viruses, 2022 The toxicity of mRNA-lipid nanoparticle (LNP) vaccines depends on the total mRNA-LNP dose. We established that the maximum tolerated dose of our trivalent mRNA-LNP genital herpes vaccine was 10 μg/immunization in mice. We then evaluated one of the mRNAs,
Lauren M. Hook +9 more
doaj +1 more source
Self‐Cooling Molecular Spin Qudits
Advanced Materials, EarlyView.A material made of [GdEr] molecular dimers can encode a qudit and perform as a magnetic refrigerant. Microwave resonant pulses coherently manipulate its 16 spin states, while direct demagnetization measurements cool the material and a device down to temperatures below 1 K.
Elías Palacios +12 more
wiley +1 more source