Results 71 to 80 of about 25,935 (265)

Extracellular vesicles released from ganglioside GD2-expressing melanoma cells enhance the malignant properties of GD2-negative melanomas

open access: yesScientific Reports, 2023
AbstractExosomes (small extracellular vesicles: EVs) have attracted increasing attention from basic scientists and clinicians since they play important roles in cell-to-cell communication in various biological processes. Various features of EVs have been elucidated regarding their contents, generation and secretion mechanisms, and functions in ...
Farhana Yesmin   +11 more
openaire   +3 more sources

Why are images smooth? [PDF]

open access: yes, 2014
It is a well observed phenomenon that natural images are smooth, in the sense that nearby pixels tend to have similar values. We describe a mathematical model of images that makes no assumptions on the nature of the environment that images depict.
Feige, Uriel
core  

The Decay Properties of the 1^{-+} Hybrid State

open access: yes, 2011
Within the framework of the QCD sum rules, we consider the three-point correlation function, work at the limit q^2 -> 0 and m_\pi -> 0, and pick out the singular term ~ {1\over q^2} to extract the pionic coupling constants of the 1^{-+} hybrid meson ...
A. A. Ovchinnikov   +7 more
core   +1 more source

Reprogramming Antitumor Immunity: NK Cell Strategies to Navigate the Immunosuppressive Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
ABSTRACT Tumor immune escape is a major barrier to durable cancer immunotherapy, as advanced malignancies create a tumor microenvironment (TME) that preferentially exhausts and disables T cell responses. While most approved cell therapies are T cell‐based, this limitation motivates the exploration of an alternative effector cell platform.
Tereza Kochs   +4 more
wiley   +1 more source

Vortex motion for the lake equations

open access: yes, 2020
The lake equations $$\left\{\begin{aligned} \nabla \cdot \big( b \, \mathbf{u}\big) &= 0 & & \text{on}\ \mathbb{R}\times D,\\ \partial_t\mathbf{u} + (\mathbf{u}\cdot \nabla)\mathbf{u} &= -\nabla h & & \text{on}\ \mathbb{R}\times D ,\\ \mathbf{u ...
Dekeyser, Justin, Van Schaftingen, Jean
core   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

Systematic Targeting of GD2‐Positive Neuroblastoma Tumors With a Photooncolytic Phage Nanovector Platform

open access: yesAdvanced Science
Disialoganglioside‐GD2 is a key molecular target for Neuroblastoma (NB) immunotherapy based on the employment of GD2‐targeting antibodies. However, about 50% of treated patients can experience tumor relapse due to limited immune‐mediated cytotoxicity and
Suleman Khan Zadran   +25 more
doaj   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Expression of GD2 and GD3 in peripheral neuroblastic tumors

open access: yesIndian Journal of Pathology and Microbiology
Purpose: The aim of this study was to explore the correlation between the expression of GD2 and GD3 and the histopathological types, risk groups, and chemotherapy in peripheral neuroblastic tumors (pNTs) and provide a theoretical basis for the selection ...
Xia Wei, Shaomei Li, Yizhen Wang
doaj   +1 more source

Dinuclear Lanthanide (III) coordination polymers in a domino reaction [PDF]

open access: yes, 2015
A systematic study was performed to further optimise the catalytic room-temperature synthesis of trans-4,5- diaminocyclopent-2-enones from 2-furaldehyde and primary or secondary amines under a non-inert atmosphere. For this purpose, a series of dinuclear
Abdul-Sada, Alaa   +5 more
core   +2 more sources

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