Results 41 to 50 of about 14,298 (222)

Neural Ganglioside GD2+ Cells Define a Subpopulation of Mesenchymal Stem Cells in Adult Murine Bone Marrow

Cellular Physiology and Biochemistry, 2013
Background/Aims: Due to the lack of specific markers, the isolation of pure mesenchymal stem cells (MSCs) from murine bone marrow remains an unsolved problem.
Jie Xu, WenJun Fan, Xi Xiang Tu, Teng Zhang, Zhi Jie Hou, Tao Guo, Xin Shu, Xi Luo, Yang Liu, Fei Peng, Chang Wang, LingZhi Xu, Han Zhou, Quentin Liu   +13 more
doaj   +1 more source

Anti-GD2 antibody dinutuximab inhibits triple-negative breast tumor growth by targeting GD2+ breast cancer stem-like cells

Journal for ImmunoTherapy of Cancer, 2021
Background Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype with no effective standard therapy. Breast cancer stem-like cells (BCSCs) in primary TNBCs are reported to be responsible for metastatic spread of the disease ...
Debasish Tripathy, Khoa Nguyen, Stanley Ly, Vivek Anand, Fouad El-Dana, Yiming Cai, Shirong Cai, Helen Piwnica-Worms, Aysegul A Sahin, Michael Andreeff, Venkata Lokesh Battula   +10 more
doaj   +1 more source

gD2-specific cellular immune responses.

, 2019
Responses to gD2 were determined using PBMCs collected at baseline (week 0), after immunisation (week 9), before booster (week 24) and after booster (week 25).
Julie L. Dutton (8138424), Neil Finlayson (8138430), Sally Kinrade (8138427), Julian Druce (4520320), David M. Koelle (8138436), Ian H. Frazer (7418663), Yan Xu (14594), Paul Griffin (3387026), Janin Chandra (3215100), Bo Li (112195), Wai-Ping Woo (466117), Kerry J. Laing (8138433)   +11 more
core   +1 more source

Expression of ganglioside GD2 on colorectal adenocarcinoma cells [PDF]

Biomeditsinskaya Khimiya, 2020
Using flow cytometry GD2 ganglioside expression was evaluated both on colorectal adenocarcinoma cell lines and on tumor tissue samples from colorectal cancer patients. The marker was found on EpCAM-positive tumor cells in 6 of 12 patients' samples but not on the HT29 and CaCo-2 cell lines. GD2 expression was not an exceptional feature of cancer stem
A Yu, Lupatov, A M, Gisina, Y S, Kim, S A, Bykasov, N N, Volchenko, D V, Sidorov, K N, Yarygin, R V, Kholodenko   +7 more
openaire   +2 more sources

Ganglioside GD2 Expression Is Associated With Unfavorable Prognosis in Early Triple-negative Breast Cancer [PDF]

三重大学博士(医学)application/pdfBackground/Aim: Gangliosides (acidic glycosphingolipids) have crucial regulatory roles in normal physiological processes, as well as in pathological conditions, including tumor onset and progression.
東, 千尋, ヒガシ, チヒロ, HIGASHI, CHIHIRO   +2 more
core   +1 more source

Ligands Binding to Cell Surface Ganglioside GD2 Cause Src-Dependent Activation of N-Methyl-D-Aspartate Receptor Signaling and Changes in Cellular Morphology. [PDF]

PLoS ONE, 2015
Ganglioside GD2 is a plasma membrane glycosphinogolipid. In healthy adults it is expressed at low levels, but it is over-expressed in many cancers. For cancer therapy, GD2 is targeted with anti-GD2 monoclonal antibodies (mAbs), and one adverse side ...
Wenyong Tong, Mario Maira, Martin Gagnon, H Uri Saragovi   +3 more
doaj   +1 more source

gD2-specific cellular immune responses to COR-1.

, 2019
Responses to gD2 were determined using PBMCs collected at baseline (week 0), after immunisation (week 9), before booster (week 24) and after booster (week 25).
Julie L. Dutton (8138424), Neil Finlayson (8138430), Sally Kinrade (8138427), Julian Druce (4520320), David M. Koelle (8138436), Ian H. Frazer (7418663), Yan Xu (14594), Paul Griffin (3387026), Janin Chandra (3215100), Bo Li (112195), Wai-Ping Woo (466117), Kerry J. Laing (8138433)   +11 more
core   +1 more source

Overall review of curative impact and barriers of CAR-T cells in osteosarcoma

EXCLI Journal : Experimental and Clinical Sciences
Osteosarcoma (OS) is a rare form of cancer and primary bone malignancy in children and adolescents. Current therapies include surgery, chemotherapy, and amputation.
Guilin Li, Hong Wang, Vafa Meftahpour
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

From the Discovery of the Giant Magnetocaloric Effect to the Development of High‐Power‐Density Systems

Advanced Materials Technologies, EarlyView.
The article overviews past and current efforts on caloric materials and systems, highlighting the contributions of Ames National Laboratory to the field. Solid‐state caloric heat pumping is an innovative method that can be implemented in a wide range of cooling and heating applications.
Agata Czernuszewicz, Yaroslav Mudryk, Jun Cui, Lucas Griffith, Duane D. Johnson, Julie Slaughter   +5 more
wiley   +1 more source