Results 181 to 190 of about 37,648 (242)

Astrocyte Mitochondrial UCP4 Reprograms Neuronal Network Oscillations via GDNF-Dependent K⁺-Ca²⁺ Signaling in Alzheimer's Disease Mice. [PDF]

Cells
Gaifullina A, Belhi C, Restivo L, Chatton JY.   +3 more
europepmc   +1 more source

Evaluation of a GDNF-eluting nanofibrous PCL conduit in a mouse model of peripheral nerve injury. [PDF]

RSC Adv
Johnson LDV, Gregory HN, Phillips JB, Memarpour Hobbi S, Boissonade FM, Claeyssens F.   +5 more
europepmc   +1 more source

A long-chain heparan sulfate capture mechanism directs paracrine GDNF-GFRα1 signalling through RET

Zol-Hanlon MI, Rix B, Bodet-Lefèvre S, Zamora-Porras M, Briggs DC, Nans A, Borg AC, Maslen SL, Di Maio A, Feizi T, Liu Y, Chopra P, Boons G, Pavljuk J, Richter RP, Schumann B, McDonald NQ.   +16 more
europepmc   +1 more source

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GDNF and Addiction

Reviews in the Neurosciences, 2005
Biochemical adaptations to drugs of abuse and alcohol are especially profound in midbrain dopaminergic neurons. Long-lasting molecular and structural changes in mesolimbic dopaminergic neurons that result from chronic exposure to drugs of abuse and alcohol are thought to underlie adverse behaviors such as compulsive drug seeking and relapse.
Dorit, Ron, Patricia H, Janak
openaire   +2 more sources

Characterization of a Multicomponent Receptor for GDNF

Nature, 1996
Glial-cell-line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons, and is essential for the development of kidneys and the enteric nervous system. Despite the potential clinical and physiological importance of GDNF, its mechanism of action is unknown.
Alun Davies, Masahide Takahashi, Naoya Asai   +2 more
exaly   +4 more sources

GDNF Isoform Affects Intracellular Trafficking and Secretion of GDNF in Neuronal Cells

Brain Research, 2008
Glial cell line derived neurotrophic factor (GDNF) plays a critical role in central and peripheral neuron survival and function. In human and rodents, GDNF exists in an alternative spliced isoform (GDNF Delta 78), which has a 78 bp deletion in the pro-region of the GDNF encoding sequence. Whether the GDNF isoform affects GDNF function is unknown. Here,
Shuhong Huang, Zhe-Yu Chen
exaly   +3 more sources

Neuroprotective and neurorestorative properties of GDNF

Annals of Neurology, 1998
AbstractGlial cell line‐derived neurotrophic factor (GDNF) promotes recovery of the injured nigrostriatal dopamine system and improves motor functions in both rodent and nonhuman primate models of Parkinson's disease (PD). The neurorestorative effects of a single administration of GDNF last for at least 1 month and can be maintained in rhesus monkeys ...
D M, Gash, Z, Zhang, G, Gerhardt
openaire   +2 more sources