Results 201 to 210 of about 36,093 (252)

Hyperuniformity and non-hyperuniformity of zeros of Gaussian Weyl-Heisenberg Functions. [PDF]

Probab Theory Relat Fields
Feldheim N, Haimi A, Koliander G, Romero JL.   +3 more
europepmc   +1 more source

De Novo <i>TRIO</i> Missense Variants Disrupt Ras-GEF Domains and Cause Congenital Ventriculomegaly and Hydrocephalus. [PDF]

Hum Mutat
Mehta NH, Dennis E, Allington G, Mekbib KY, Hale AT, Davalan WC, Duy PQ, Zilla E, Fan B, Kasper EM, Alper SL, Haider S, Kahle KT.   +12 more
europepmc   +1 more source

Taxane-Induced Conformational Changes in the Microtubule Lattice Activate GEF-H1-Dependent RhoA Signaling

Meiring JCM, Mahapatra V, Gravett MS, Morren D, Saunders HA, Choi SR, José AP, Karhanova A, Metallidou I, Moore A, Spoelstra MF, Liu R, Giono M, Iyer SS, Díaz JF, Lansky Z, Stecker KE, Steinmetz MO, Howes SC, Kapitein LC, Akhmanova A.   +20 more
europepmc   +1 more source

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Decoding GEFs of animated cells

Nature Chemical Biology, 2020
Rho family GTPases regulate cell behaviors through complex signaling networks that act on rapid timescales in subcellular spatial domains. New live-cell biosensors and analytical methods now provide critical tools to dissect Rho GTPase regulation and to better understand cellular information processing.
Dean E. Natwick, Sean R. Collins
openaire   +2 more sources

In Vitro GEF and GAP Assays

Current Protocols in Cell Biology, 2009
AbstractSmall GTPases act as tightly regulated molecular switches governing a large variety of critical cellular functions. Their activity is controlled by two different biochemical reactions, GDP/GTP exchange and GTP hydrolysis. These very slow reactions require catalysis in cells by two kinds of regulatory proteins.
Alexander, Eberth, Mohammad Reza, Ahmadian   +1 more
openaire   +2 more sources

General Enterprise Framework (GEF)

Proceedings of 2012 IEEE International Conference on Service Operations and Logistics, and Informatics, 2012
We present a technique in the domain of the business architecture of enterprises. It is called GEF (General Enterprise Framework) because it intends to be universal and to apply at whole enterprise. GEF is a grid where the activities of business processes are classified into five levels - Plan, Execute, Monitor, Control, Manage information. In an ideal
Gianmario Motta, Daniele Sacco, Thiago Barroero   +2 more
openaire   +2 more sources

GEFs in growth factor signaling

Growth Factors, 2007
Evolutionary conserved members of the Ras superfamily of small GTP-binding proteins function as binary molecular switches to control diverse biological processes. In the context of cellular signaling, these include functions in exocytic and endocytic trafficking, as well as roles in signal relay downstream of various cell surface receptors.
André, Bernards, Jeffrey, Settleman
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Catching a GEF by its tail

Trends in Cell Biology, 2007
The activation of Rho GTPases is mediated by guanine-nucleotide exchange factors (GEFs), which catalyze the exchange of GDP for GTP. Rho-GEFs are a very diverse family, with >70 members in humans. Bioinformatics analysis of the human Rho-GEFs shows that approximately 40% contain a putative PDZ-binding motif at the C-terminus.
Rafael, García-Mata, Keith, Burridge
openaire   +2 more sources

Abstract Mechanisms of GEF and Techniques for GEF Based Graphical Editors

2012
The Graphical Editor Framework (GEF) is a popular framework built to develop rich graphical editor for models. But being lack of detailed documentation, it is difficult to use GEF in practice. In this paper, the principle, composition and main classes (interfaces) of GEF were analyzed. The three levels of abstract mechanisms of GEF were studied.
Deren Yang, Min Zhou, Fen Chen, Jianping Ma   +3 more
openaire   +1 more source