Results 151 to 160 of about 2,223,573 (201)

Optimizing response to gefitinib in the treatment of non-small-cell lung cancer

, 2011
Pietro Carotenuto1, Cristin Roma1, Anna Maria Rachiglio1, Raffaella Pasquale1, Renato Franco2, Giuseppe Antinolfi3, Francovito Piantedosi4, Alfonso Illiano5, Gerardo Botti2, Alessandro Morabito6, Nicola Normanno7, Antonella De Luca71Pharmacogenomic ...
et al, Cristin Roma, Anna Maria Rachiglio, Pietro Carotenuto   +3 more
core  

SLC16A3 drives lung adenocarcinoma progression and gefitinib resistance through coordinated regulation of ferroptosis and lactate metabolism. [PDF]

Front Immunol
Cai W, Liu Y, Zhao K, Zhu Z, Jin J, Wen J, Xue Z.   +6 more
europepmc   +1 more source

Integrin alpha5beta1 and resistance to cancer therapies: role of endocytosis in resistance to gefitinib

, 2017
Glioblastoma is an aggressive, invasive and resistant brain cancer. Despite the promisor role of EGFR, targeted therapies failed without giving insights about predictive factors. EGFR endocytosis and trafficking have been reported to influenciate therapy resistance. Integrin is known as a regulator of EGFR oncogenic activity during tumor progression by
openaire   +1 more source

MiR-493-3p suppresses the DPY-30 histone methyltransferase complex regulatory subunit to attenuate gefitinib resistance in lung cancer. [PDF]

Transl Oncol
Munyembaraga V, Mhone TG, Yu YL, Chen MC, Kuo CH, Hsieh DJ, Lin KH, Ho TJ, Kuo WW, Huang CY.   +9 more
europepmc   +1 more source

Losmapimod: A Novel Clinical Drug to Overcome Gefitinib-Resistance

EBioMedicine, 2018
openaire   +3 more sources

LY2874455 and Abemaciclib Reverse FGF3/4/19/CCND1 Amplification Mediated Gefitinib Resistance in NSCLC. [PDF]

Front Pharmacol, 2022
Liu D, Liu H, Gan J, Zeng S, Zhong F, Zhang B, Zhang Z, Zhang S, Jiang L, Wang G, Chen Y, Kong FS, Fang W, Wang L.   +13 more
europepmc   +1 more source

[Retracted] Tumor‑released lncRNA H19 promotes gefitinib resistance via packaging into exosomes in non‑small cell lung cancer. [PDF]

Oncol Rep
Lei Y, Guo W, Chen B, Chen L, Gong J, Li W.   +5 more
europepmc   +1 more source

VDR Decrease Enhances the Efficacy of 1,25-Dihydroxyvitamin D3 Inhibiting Gefitinib Resistance by Regulating EGFR/FASN Loop in NSCLC Cells. [PDF]

Pharmaceuticals (Basel)
Yang J, Fang M, Hou M, Duan Y, Wang J, Hu K, Liu S, Liu X, Peng X, Ding X, Jia Z.   +10 more
europepmc   +1 more source

β-Elemene Reverses Gefitinib Resistance in NSCLC Cells by Inhibiting lncRNA H19-Mediated Autophagy. [PDF]

Pharmaceuticals (Basel)
Zhang R, Zheng Y, Zhu Q, Gu X, Xiang B, Gu X, Xie T, Sui X.   +7 more
europepmc   +1 more source

The screening and characterization of aptamer against gefitinib-resistant cells

Annals of Oncology, 2017
Y.-L. Chen, J.-E. Wu, T.-M. Hong
openaire   +1 more source