Results 141 to 150 of about 2,223,573 (201)

Relationship between Mutations of the Epidermal Growth Factor Receptor Gene and Drug-Resistance to Gefitinib in Human Lung Cancer in vitro

open access: yesChinese Journal of Lung Cancer, 2009
Background and objective To explore cell lines' difference of drug-resistance to gefitinib and the underlying mechanism. Methods Human lung cancer cell lines of PC9, PC9/AB2, PC9/AB11, PC9/BB4 were treated in vitro , exons 18-21 of EGFR gene were ...
Wei WEI   +7 more
doaj  

Farnesyltransferase inhibitor LB42708 disables oncogenic RAS signaling and overcomes gefitinib resistance in NSCLC via FTase α-subunit and RAS degradation. [PDF]

open access: yesCell Commun Signal
Luo G   +23 more
europepmc   +1 more source

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