Results 111 to 120 of about 7,559 (252)

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Carbonated Fluorapatite‐Gelatin‐Composites: Morphogenesis and Structure of Kniep's Dumbbells

Zeitschrift für anorganische und allgemeine Chemie, EarlyView.
Inspired by the pioneering work of Prof. Rüdiger Kniep on fluorapatite‐gelatin nanocomposites also known as “Kniep's Dumbbells,” this study investigates carbonated fluorapatite‐gelatin aggregates synthesized by the double diffusion technique within a gelatin gel.
Elena V. Sturm, Wilder Carrillo‐Cabrera, Olga V. Frank‐Kamenetskaya, Dirk Zahn, Wolfgang W. Schmahl, Erika Griesshaber, Paul Simon   +6 more
wiley   +1 more source

Favorable alleles mining for gelatinization temperature, gel consistency and amylose content in Oryza sativa by association mapping. [PDF]

BMC Genet, 2019
Wang H, Zhu S, Dang X, Liu E, Hu X, Eltahawy MS, Zaid IU, Hong D.   +7 more
europepmc   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

Ants contribute to raspberry pollination in protected cropping systems

Agricultural and Forest Entomology, EarlyView.
Ants visited raspberry flowers more frequently than European honey bees (Apis mellifera), Australian stingless bees (Tetragonula carbonaria) and flies, many transporting raspberry pollen on their bodies, indicating potential pollination capacity. Ants were active flower visitors at most times of the day and may extend the daily pollination window and ...
Pia Malm, Blake M. Dawson, Jelena Preradovic, Johan Ekroos, Romina Rader, Bar Shermeister, Lena A. Schmidt   +6 more
wiley   +1 more source

Cannabinoid and adenosine A2A receptor crosstalk regulates postnatal and adult hippocampal neurogenesis

British Journal of Pharmacology, EarlyView.
Background and purpose Adult neurogenesis is a tightly regulated process affected by both cannabinoid receptors (CB1 and CB2) and adenosine 2A (A2A) receptors, both of which modulate neural progenitor cell activity. While emerging evidence suggests an interaction between these neuromodulatory systems, the extent and mechanism of their interplay in ...
Rui S. Rodrigues, Adam Armada‐Moreira, Laura Gómez‐Acero, Filipa F. Ribeiro, Francisco M. Mouro, Ana M. Sebastião, Francisco Ciruela, Ester Aso, Sara Xapelli   +8 more
wiley   +1 more source

The selective degradation of PDE4B shortform, using a PROTAC, leads to inhibition of several hallmarks of cancer in HCT116 cells

British Journal of Pharmacology, EarlyView.
Background and Purpose Colorectal cancer is one of the most prevalent cancers worldwide, and novel precision medicine approaches are rapidly improving patient outcomes. Phosphodiesterase 4B (PDE4B) is a member of an enzyme family (PDE4) that hydrolyses intracellular cAMP to control spatial and temporal signalling cues.
Alina Zorn, John Daniel Pediani, Madihah Hussain, Jiayue Ling, Elaine Brown, Igor Belka, Eduardo Torres, Cathy Swindlehurst, Kyle Chan, David Stirling, George S. Baillie, Yuan Yan Sin   +11 more
wiley   +1 more source

A Review of Nonsteroidal Anti‐Inflammatory Drugs for Food‐Producing Animals With a Focus on Potential Applications for Farmed Finfish

Journal of Fish Diseases, EarlyView.
ABSTRACT In finfish aquaculture, there are several inflammatory diseases impacting productivity and animal welfare, however there are limited options available to veterinarians to treat inflammation and pain in fish. Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used in terrestrial animals raised for human consumption to treat a range of ...
Chloe J. English, Christine Huynh, William Roy, James W. Wynne, Hamish Rodger   +4 more
wiley   +1 more source

Chloroplast and mitochondrial genomes of Sphaerosorus coelastroides Pascher (Xanthophyceae) from Central Appalachia, Clinch River, Virginia, United States

Journal of Phycology, EarlyView.
Abstract This report describes the isolation and culture of Sphaerosorus coelastroides from the plankton of a freshwater river in the central Appalachian mountain chain. This alga was first observed in a dry freshwater riverbed in Central Europe in 1908 and, since then, has been included in Xanthophyceae surveys from nearly all continents with ...
Gavin S. Collins, Robin A. Matthews, A. Bruce Cahoon   +2 more
wiley   +1 more source

Conserved symbiosis‐associated genes in the cycad Encephalartos natalensis suggest co‐option for cyanobacterial symbiosis

New Phytologist, EarlyView.
The heterocyst‐rich Encephalartos natalensis cyanobacterial zone in coralloid root suggests co‐option of conserved symbiosis‐associated genes. This figure was created in BioRender (BioRender.com/https://BioRender.com/n3qveqc). Summary Plant‐cyanobacterial symbioses have evolved independently at least four times across land plants, yet their underlying ...
Cassandra Schoeman, Danielle Roodt, Amy Mc Menamin, Oliver Bezuidt, Choaro Dithugoe, Desré Pinard, Eshchar Mizrachi   +6 more
wiley   +1 more source