Neurobiology of Disease, 2013 Interactions between genetic factors and environmental exposures are thought to be major contributors to the etiology of Parkinson's disease. While such interactions are poorly defined and incompletely understood, recent epidemiological studies have ...
Jason R. Cannon, J. Timothy Greenamyre
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Social Integration and Sleep Disturbance: A Gene-Environment Interaction Study
Collabra, 2016 Objective: Low levels of perceived social integration, or loneliness, are associated with increased risk for a range of poor health outcomes. Sleep disturbance plays a central role in the evolutionary theory of loneliness, which provides a mechanistic ...
David A. Sbarra
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Requirement of a Plasmid-Encoded Catalase for Survival of \u3cem\u3eRhizobium etli\u3c/em\u3e CFN42 in a Polyphenol-Rich Environment [PDF]
, 2008 Nitrogen-fixing bacteria collectively called rhizobia are adapted to live in polyphenol-rich environments. The mechanisms that allow these bacteria to overcome toxic concentrations of plant polyphenols have not been clearly elucidated.
Brom, Susana +5 more
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Evolved polygenic herbicide resistance in Lolium rigidum by low-dose herbicide selection within standing genetic variation [PDF]
, 2012 The interaction between environment and genetic traits under selection is the basis of evolution. In this study, we have investigated the genetic basis of herbicide resistance in a highly characterized initially herbicide-susceptible Lolium rigidum ...
Darmency H. +3 more
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Gene-environment interaction and maternal arsenic methylation efficiency during pregnancy
Environment International, 2019 Background: Single nucleotide polymorphisms (SNPs) may influence arsenic methylation efficiency, affecting arsenic metabolism. Whether gene-environment interactions affect arsenic metabolism during pregnancy remains unclear, which may have implications ...
Shangzhi Gao +9 more
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Robust tests for gene–environment interaction in case-control and case-only designs [PDF]
, 2019 The case-control and case-only designs are commonly used to detect the gene–environment (G–E) interaction. In principle, the tests based on these two designs require a pre-specified genetic model to achieve an expected power of detecting the G–E ...
Cao, Sha +4 more
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Exploiting Gene-Environment Independence for Analysis of Case-Control Studies: An Empirical Bayes Approach to Trade Off between Bias and Efficiency [PDF]
, 2006 Standard prospective logistic regression analysis of case-control data often leads to very imprecise estimates of gene-environment interactions due to small numbers of cases or controls in cells of crossing genotype and exposure.
Mukherjee, Bhramar
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Epigenetic metaphors: an interdisciplinary translation of encoding and decoding
New Genetics and Society, 2019 Looking at the new and often disputed science of epigenetics, we examined the challenges faced by scientists when they communicate scientific research to the public. We focused on the use of metaphors to illustrate notions of epigenetics and genetics. We
Aviad Raz +2 more
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Gene variants with suicidal risk in a sample of subjects with chronic migraine and affective temperamental dysregulation [PDF]
, 2012 BACKGROUND: Risk factors for suicide are at least partially heritable and functional polymorphisms of targeted genes have been suggested to be implicated in the pathogenesis of this phenomenon.
BORRO, Marina +10 more
core
Frontiers in AgingBackgroundOsteoporosis is a complex disease influenced by genetic variants, environmental factors, and comorbidities. While individual single-nucleotide variants (SNVs) have been associated with disease risk, limited data are available on how gene–gene ...
Antonio Miranda-Duarte +8 more
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