Differential expression of placental glucocorticoid receptors and growth arrest-specific transcript 5 in term and preterm pregnancies: evidence for involvement of maternal stress. [PDF]
, 2014 This article has been made available through the Brunel Open Access Publishing Fund.Pregnancy-specific stress predicts birth outcomes. We hypothesized that there is a maternal stress-GR interaction that can influence fetal birth weight.
Gidron, Y +6 more
core +3 more sources
PLoS Genetics, 2016 How combinations of gene-environment interactions collectively give rise to genotype-environment interactions is not fully understood. To shed light on this problem, we genetically dissected an environment-specific poor growth phenotype in a cross of two
Takeshi Matsui, Ian M Ehrenreich
doaj +1 more source
Refining the scope of genetic influences on alcohol misuse through environmental stratification and gene-environment interaction. [PDF]
Alcohol Clin Exp Res (Hoboken)Savage JE +6 more
europepmc +3 more sources
Gene-environment interaction effects on lung function- a genome-wide association study within the Framingham heart study [PDF]
, 2013 Background: Previous studies in occupational exposure and lung function have focused only on the main effect of occupational exposure or genetics on lung function.
Christiani, David C +2 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed +5 more
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
IPRS: Leveraging Gene-Environment Interaction to Reconstruct Polygenic Risk Score
Frontiers in Genetics, 2022 Background: Polygenic risk score (PRS) is widely regarded as a predictor of genetic susceptibility to disease, applied to individuals to predict the risk of disease occurrence.
Yingdan Tang +6 more
doaj +1 more source
Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis [PDF]
, 2013 Introduction: The objective was to investigate potential gene-environment interaction between body mass index (BMI) and each of eight TGFβ1 polymorphisms in knee and hip osteoarthritis (OA).
Doherty, Michael +5 more
core +5 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
The Role of Genes in Defining a Molecular Biology of PTSD [PDF]
, 2014 Because environmental exposure to trauma is the sine qua non for the development of Post Traumatic Stress Disorder (PTSD), the recent focus on genetic studies has been noteworthy. The main catalyst for such studies is the observation from epidemiological
Flory, Janine D. +3 more
core +1 more source