Background Gamma-aminobutyric acid type A (GABAA) receptors mainly mediate the effects of gamma-aminobutyric acid, which is the primary inhibitory neurotransmitter in the central nervous system.
Sheue-Jane Hou +7 more
doaj +1 more source
Cross-cultural comparison of genetic and cultural transmission of smoking initiation using an extended twin kinship model [PDF]
Background: Considerable evidence from twin and adoption studies indicates that genetic and shared environmental factors play a role in the initiation of smoking behavior.
Eaves, Lindon J +6 more
core +2 more sources
Random regression models for detection of gene by environment interaction
Two random regression models, where the effect of a putative QTL was regressed on an environmental gradient, are described. The first model estimates the correlation between intercept and slope of the random regression, while the other model restricts ...
Meuwissen Theo HE +2 more
doaj +1 more source
Genetic Influences on Peer and Family Relationships across Adolescent Development: Introduction to the Special Issue [PDF]
Nearly all aspects of human development are influenced by genetic and environmental factors, which conjointly shape development through several gene-environment interplay mechanisms.
DiLalla, Lisabeth Fisher +1 more
core +2 more sources
Emergent adaptive behaviour of GRN-controlled simulated robots in a changing environment [PDF]
We developed a bio-inspired robot controller combining an artificial genome with an agent-based control system. The genome encodes a gene regulatory network (GRN) that is switched on by environmental cues and, following the rules of transcriptional ...
Marchal, Kathleen +3 more
core +4 more sources
A new clinical evidence-based gene-environment interaction model of depression. [PDF]
In our current understanding of mood disorders, the role of genes is diverse including the mediation of the effects of provoking and protective factors.
Bagdy, György +2 more
core
Nature, Nurture and Egalitarian Policy: What Can We Learn from Molecular Genetics? [PDF]
This brief paper draws attention to molecular genetic research which may provide a new dimension to our understanding of how socioeconomic outcomes are generated. In particular, we provide an overview of the recently emerging evidence of gene-environment
Lundborg, Petter, Stenberg, Anders
core
Expanding the modern synthesis II: Formal perspectives on the inherent role of niche construction in fitness [PDF]
Expanding the modern synthesis requires elevating the role of interaction within and across various biological scales to the status of an evolutionary principle.
Rodrick Wallace
core +1 more source
Common Genetic Variant Association with Altered HLA Expression, Synergy with Pyrethroid Exposure, and Risk for Parkinson's Disease: An Observational and Case-Control Study. [PDF]
Background/objectivesThe common non-coding single nucleotide polymorphism (SNP) rs3129882 in HLA-DRA is associated with risk for idiopathic Parkinson's disease (PD).
Boss, JM +11 more
core +2 more sources
Tests for Gene-Environment Interactions and Joint Effects with Exposure Misclassification [PDF]
The number of methods for genome-wide testing of gene-environment interactions (GEI) continues to increase with the hope of discovering new genetic risk factors and obtaining insight into the disease-gene-environment relationship.
Ahn, Jaeil +5 more
core +2 more sources

