Results 21 to 30 of about 1,095,697 (331)
A flexible Bayesian model for studying gene-environment interaction. [PDF]
PLoS Genetics, 2012 An important follow-up step after genetic markers are found to be associated with a disease outcome is a more detailed analysis investigating how the implicated gene or chromosomal region and an established environment risk factor interact to influence ...
Kai Yu +6 more
doaj +1 more source
Hawaiian Picture‐Winged Drosophila Exhibit Adaptive Population Divergence along a Narrow Climatic Gradient on Hawaii Island [PDF]
, 2019 1. Anthropogenic influences on global processes and climatic conditions are increasingly affecting ecosystems throughout the world. 2. Hawaii Island’s native ecosystems are well studied and local long‐term climatic trends well documented, making these ...
Bellinger, M. Renee +2 more
core +2 more sources
Gene–environment interactions in asthma [PDF]
Occupational and Environmental Medicine, 2006 Asthma is a complex disease with a diverse genetic and environmental component.1 Asthma shows a high level of phenotypic heterogeneity characterised by obstruction of the airways of the lung and is related with atopy, bronchial hyperresponsiveness (BHR), and increased IgE levels.
Manolis Kogevinas +3 more
openaire +3 more sources
Interactions between Polygenic Scores and Environments: Methodological and Conceptual Challenges
Sociological Science, 2020 Interest in the study of gene–environment interaction has recently grown due to the sudden availability of molecular genetic data—in particular, polygenic scores—in many long-running longitudinal studies.
Benjamin W. Domingue +3 more
doaj +1 more source
Alcohol consumption and lifetime change in cognitive ability:a gene × environment interaction study [PDF]
, 2014 Studies of the effect of alcohol consumption on cognitive ability are often confounded. One approach to avoid confounding is the Mendelian randomization design.
AJ Birley +39 more
core +1 more source
Candidate gene-environment interactions in substance abuse: A systematic review.
PLoS ONE, 2023 BackgroundThe abuse of psychogenic drugs can lead to multiple health-related problems. Genetic and environmental vulnerabilities are factors in the emergence of substance use disorders.
Zheng Jiang, Zidong Chen, Xi Chen
doaj +1 more source
Metabolic syndrome, diabetes and atherosclerosis: Influence of gene-environment interaction [PDF]
, 2009 Despite remarkable progress in diagnosis and understanding of risk factors, cardiovascular disease (CVD) remains still the leading cause of morbidity and mortality in the world\u27s developed countries.
Andreassi, Maria Grazia
core +1 more source
Gene environment interactions in asthma [PDF]
Archives of Disease in Childhood, 2007 The underlying pathogenesis of asthma, one of the most common chronic diseases of childhood, is not fully understood. There is a well-documented heritable component to this disease and environmental factors associated with a Westernised lifestyle have also been implicated; recent studies suggest gene-environment interactions are important in the ...
S Turner, S McLeish
openaire +3 more sources
Artificial neural networks modeling gene-environment interaction
BMC Genetics, 2012 Background Gene-environment interactions play an important role in the etiological pathway of complex diseases. An appropriate statistical method for handling a wide variety of complex situations involving interactions between variables is still lacking,
Günther Frauke +2 more
doaj +1 more source
Breast Cancer Research, 2023 Background Moderate to heavy alcohol consumption is associated with an increased risk of breast cancer. The etiologic role of genetic variation in genes involved in ethanol metabolism has not been established, with little information available among ...
Kristin L. Young +8 more
doaj +1 more source