Results 11 to 20 of about 2,560,285 (288)
Communications Biology, 2022 Mito-SiPE is a mitochondrial DNA (mtDNA) enrichment method that can derive high-quality mtDNA for rare heteroplasmy analysis, without relying on PCR or probes.
Darren J. Walsh +6 more
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Gene–gene and gene-environment interactions on cord blood total IgE in Chinese Han children
Allergy, Asthma & Clinical Immunology, 2021 Background IL13, IL4, IL4RA, FCER1B and ADRB2 are susceptible genes of asthma and atopy. Our previous study has found gene–gene interactions on asthma between these genes in Chinese Han children. Whether the interactions begin in fetal stage, and whether
Li Hua +18 more
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Gene-environment interaction in yeast gene expression. [PDF]
PLoS Biology, 2008 The effects of genetic variants on phenotypic traits often depend on environmental and physiological conditions, but such gene-environment interactions are poorly understood.
Erin N Smith, Leonid Kruglyak
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Analysis of Gene‐Gene Interactions [PDF]
Current Protocols in Human Genetics, 2011 AbstractThe goal of this unit is to introduce gene‐gene interactions (epistasis) as a significant complicating factor in the search for disease susceptibility genes. This unit begins with an overview of gene‐gene interactions and why they are likely to be common.
Diane, Gilbert-Diamond, Jason H, Moore
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Identifying gene interaction enrichment for gene expression data. [PDF]
PLoS ONE, 2009 Gene set analysis allows the inclusion of knowledge from established gene sets, such as gene pathways, and potentially improves the power of detecting differentially expressed genes.
Jigang Zhang, Jian Li, Hong-Wen Deng
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Multivariate Detection of Gene‐Gene Interactions [PDF]
Genetic Epidemiology, 2012 Unraveling the nature of genetic interactions is crucial to obtaining a more complete picture of complex diseases. It is thought that gene‐gene interactions play an important role in the etiology of cancer, cardiovascular, and immune‐mediated disease.
Indika, Rajapakse +4 more
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How ambient temperature affects the heading date of foxtail millet (Setaria italica)
Frontiers in Plant Science, 2023 Foxtail millet (Setaria italica), a short-day plant, is one of the important crops for food security encountering climate change, particularly in regions where it is a staple food.
Ya-Chen Huang +8 more
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Eigen-Epistasis for detecting gene-gene interactions [PDF]
BMC Bioinformatics, 2017 A large amount of research has been devoted to the detection and investigation of epistatic interactions in genome-wide association studies (GWASs). Most of the literature focuses on low-order interactions between single-nucleotide polymorphisms (SNPs) with significant main effects.In this paper we propose an original approach for detecting epistasis ...
Stanislas, Virginie +2 more
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Gene–gene interactions in breast cancer susceptibility [PDF]
Human Molecular Genetics, 2011 There have been few definitive examples of gene-gene interactions in humans. Through mutational analyses in 7325 individuals, we report four interactions (defined as departures from a multiplicative model) between mutations in the breast cancer susceptibility genes ATM and CHEK2 with BRCA1 and BRCA2 (case-only interaction between ATM and BRCA1/BRCA2 ...
Turnbull C +39 more
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Cell Reports, 2019 Summary: MicroRNA (miRNA) processing begins with Drosha cleavage, the fidelity of which is critical for downstream processing and mature miRNA target specificity.
Xavier Bofill-De Ros +11 more
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