Results 81 to 90 of about 5,291,226 (319)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Production of EPSPS and bar gene double-herbicide resistant castor (Ricinus communis L.)

Biotechnology & Biotechnological Equipment, 2020
Castor (Ricinus communis L.) is one of the world's top ten oil crops. China is the second largest producer of castor beans, but China's castor bean acreage has been declining. A principal reason for this decline is the prevalence of weeds and the absence
Huibo Zhao, Yong Zhao, Rui Luo, Lifeng Yang, Guorui Li, Jianjun Di, Mu Peng, Lili Li, Qi Wen, Xiaotian Liang, Mingda Yin, Yanpeng Wen, Fenglan Huang   +12 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Targeted Disruption of the Type 2 Selenodeiodinase Gene (DIO2) Results in a Phenotype of Pituitary Resistance to T₄ [PDF]

, 2001
Mark J. Schneider, Steven Fiering, Sophie Pallud, Albert F. Parlow, Donald L. St. Germain, Valerie Anne Galton   +5 more
openalex   +1 more source

DNA Transfection : Gene Regulation, Gene Amplification and Gene Cloning

Juntendo Medical Journal, 1986
DNA transfection is a powerful tool of gene analysis. Indeed it allows functional studies of genes either from high molecular weight cellular DNA ( i. e. in their physiological structure) or cloned in vectors ( i. e. amenable to manipulations designed to influence their function ).
Saverio Alberti, Leonard A. Herzenberg
openaire   +3 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Association of single nucleotide variants of the SLCO1B1 gene with the Gilbert syndrome phenotype

Бюллетень сибирской медицины
The aim of the study is to investigate the association of rs2306283 and rs4149056 variants of the SLCO1B1 gene with benign unconjugated hyperbilirubinemia. Materials and methods. A case-control study design was employed.
A. A. Ivanova, N. E. Apartseva, A. P. Kashirina, E. G. Nemtsova, Yu. V. Ivanova, M. V. Kruchinina, S. A. Kurilovich, V. N. Maksimov   +7 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

New Perspectives on Diagnosis and Therapy of Malignant Pleural Mesothelioma

Frontiers in Oncology, 2018
Malignant pleural mesothelioma (MPM) is a rare, but severe form of cancer, with an incidence that varies significantly within and among different countries around the world.
Marika Rossini, Paola Rizzo, Ilaria Bononi, Anthony Clementz, Roberto Ferrari, Roberto Ferrari, Fernanda Martini, Mauro G. Tognon   +7 more
doaj   +1 more source

Regulation of Flavonoid Biosynthetic Genes in Germinating Arabidopsis Seedlings. [PDF]

, 1992
William Kubasek, A. Winkel, Ann McKillop, H. M. Goodman, Winslow R. Briggs, Frederick M. Ausubel   +5 more
openalex   +1 more source