An RNA-DNA Complex Intermediate in Ribosomal Gene Amplification [PDF]
Vijak Mahdavi, Marco Crippa
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Simulating multiple faceted variability in single cell RNA sequencing. [PDF]
The abundance of new computational methods for processing and interpreting transcriptomes at a single cell level raises the need for in silico platforms for evaluation and validation.
Xu, Chenling, Yosef, Nir, Zhang, Xiuwei
core
Amplification enhancers and replication origins in the autosomal chorion gene cluster of Drosophila. [PDF]
Christos Delidakis, Fotis C. Kafatos
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Purpose: The epidermal growth factor receptor (EGFR) is overexpressed in the majority of nonsmall-cell lung cancers (NSCLC) and is a major target specific EGFR tyrosine kinase inhibitors (TKIs) developed and used for the treatment of advanced NSCLC.
Patrícia Couceiro+4 more
doaj
Assessment of Cyclin E Gene Amplification as a Biomarker in Isfahan Province Breast Cancer Patients [PDF]
Background & Objective: Breast cancer is the most common cancer among women worldwide. Cell-cycle is controlled by regulatory proteins called cyclins and Cyclin-Dependent Kinases. Aberrant activity of cyclins plays an important role in cancer development
Goharik Torosian+2 more
doaj
Structure and expression of amplified cKi-ras gene sequences in Y1 mouse adrenal tumor cells. [PDF]
Donna L. George+5 more
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Somatic recombination, gene amplification and cancer
The principle objective of this research programme, to analyse chemical induction of somatic recombination and related endpoints, i.e., mobilization of transposing elements and gene amplification, has been approached by means of several assay systems. These have included Drosophila, Saccharomyces and mammalian cell cultures. 6.1.
Håkan Cederberg+12 more
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Direct introduction of cloned DNA into the sea urchin zygote nucleus, and fate of injected DNA [PDF]
A method is described for microinjection of cloned DNA into the zygote nucleus of Lytechinus variegatus. Eggs of this species are unusually transparent, facilitating visual monitoring of the injection process.
Britten, Roy J.+3 more
core
Characterization of DNA rearrangements of N‐myc gene amplification in three neuroblastoma cell lines by pulsed‐field gel electrophoresis [PDF]
Hiroshi Kato+4 more
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The PVT gene frequently amplifies with MYC in tumor cells. [PDF]
Emma Shtivelman, J. Michael Bishop
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