Results 111 to 120 of about 7,371,567 (249)

Simulating multiple faceted variability in single cell RNA sequencing. [PDF]

open access: yes, 2019
The abundance of new computational methods for processing and interpreting transcriptomes at a single cell level raises the need for in silico platforms for evaluation and validation.
Xu, Chenling, Yosef, Nir, Zhang, Xiuwei
core  

Polysomy and amplification of chromosome 7 defined for EGFR gene in squamous cell carcinoma of the lung together with exons 19 and 21 wild type Carcinoma epidermóide do pulmão: Polissomia e amplificação do cromossoma 7 e do gene EGRF com forma wild type nos exões 19 e 21

open access: yesRevista Portuguesa de Pneumologia, 2010
Purpose: The epidermal growth factor receptor (EGFR) is overexpressed in the majority of nonsmall-cell lung cancers (NSCLC) and is a major target specific EGFR tyrosine kinase inhibitors (TKIs) developed and used for the treatment of advanced NSCLC.
Patrícia Couceiro   +4 more
doaj  

Assessment of Cyclin E Gene Amplification as a Biomarker in Isfahan Province Breast Cancer Patients [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2020
Background & Objective: Breast cancer is the most common cancer among women worldwide. Cell-cycle is controlled by regulatory proteins called cyclins and Cyclin-Dependent Kinases. Aberrant activity of cyclins plays an important role in cancer development
Goharik Torosian   +2 more
doaj  

Structure and expression of amplified cKi-ras gene sequences in Y1 mouse adrenal tumor cells. [PDF]

open access: bronze, 1985
Donna L. George   +5 more
openalex   +1 more source

Somatic recombination, gene amplification and cancer

open access: yesMutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1996
The principle objective of this research programme, to analyse chemical induction of somatic recombination and related endpoints, i.e., mobilization of transposing elements and gene amplification, has been approached by means of several assay systems. These have included Drosophila, Saccharomyces and mammalian cell cultures. 6.1.
Håkan Cederberg   +12 more
openaire   +5 more sources

Direct introduction of cloned DNA into the sea urchin zygote nucleus, and fate of injected DNA [PDF]

open access: yes, 1988
A method is described for microinjection of cloned DNA into the zygote nucleus of Lytechinus variegatus. Eggs of this species are unusually transparent, facilitating visual monitoring of the injection process.
Britten, Roy J.   +3 more
core  

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