Results 71 to 80 of about 566,833 (345)

Maize microarray annotation database

Plant Methods, 2011
Background Microarray technology has matured over the past fifteen years into a cost-effective solution with established data analysis protocols for global gene expression profiling.
Berger Dave K, Myburg Alexander A, Coetzer Nanette   +2 more
doaj   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

GARNET – gene set analysis with exploration of annotation relations

BMC Bioinformatics, 2011
Background Gene set analysis is a powerful method of deducing biological meaning for an a priori defined set of genes. Numerous tools have been developed to test statistical enrichment or depletion in specific pathways or gene ontology (GO) terms.
Seo Jihae, Bae Taejeong, Lee Sanghyun, Jang Youngjun, Kim Bumjin, Rho Kyoohyoung, Seo Chaehwa, Lee Jihyun, Kang Hyunjung, Yu Ungsik, Kim Sunghoon, Lee Sanghyuk, Kim Wan Kyu   +12 more
doaj   +1 more source

DROPA: DRIP-seq optimized peak annotator

BMC Bioinformatics, 2019
Background R-loops are three-stranded nucleic acid structures that usually form during transcription and that may lead to gene regulation or genome instability.
Marco Russo, Bruno De Lucca, Tiziano Flati, Silvia Gioiosa, Giovanni Chillemi, Giovanni Capranico   +5 more
doaj   +1 more source

Gene and alternative splicing annotation with AIR [PDF]

Genome Research, 2005
Designing effective and accurate tools for identifying the functional and structural elements in a genome remains at the frontier of genome annotation owing to incompleteness and inaccuracy of the data, limitations in the computational models, and shifting paradigms in genomics, such as alternative splicing.
Ian M. Dew, Brian P. Walenz, Liliana Florea, Granger G. Sutton, Alison Yao, Rosane Charlab, Clark M. Mobarry, Valentina Di Francesco, Russell Turner, Peter W. Li, Sorin Istrail, Jason R. Miller, Gennady V. Merkulov, Michael Harris, Zuoming Deng   +14 more
openaire   +3 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Gene Annotation Easy Viewer (GAEV): Integrating KEGG’s Gene Function Annotations and Associated Molecular Pathways [version 2; referees: 1 approved, 2 approved with reservations]

F1000Research, 2018
We developed a Gene Annotation Easy Viewer (GAEV) that integrates the gene annotation data from the KEGG (Kyoto Encyclopedia of Genes and Genomes) Automatic Annotation Server.
Trung Huynh, Sen Xu
doaj   +1 more source

GNPAnnot community annotation system applied to sugarcane bac clone sequences (W572) [PDF]

, 2011
A large amount of data is being produced by current genome sequencing projects. Sequence annotations and analyses need to be organized into databases and widely accessible.
Bocs, Stéphanie, Charron, Carine, D'Hont, Angélique, Droc, Gaëtan, Garsmeur, Olivier, Guignon, Valentin   +5 more
core  

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Gene Annotation Easy Viewer (GAEV): Integrating KEGG’s Gene Function Annotations and Associated Molecular Pathways [version 3; peer review: 1 approved, 2 approved with reservations]

F1000Research, 2019
We developed a Gene Annotation Easy Viewer (GAEV) that integrates the gene annotation data from the KEGG (Kyoto Encyclopedia of Genes and Genomes) Automatic Annotation Server.
Trung Huynh, Sen Xu
doaj   +1 more source