Results 61 to 70 of about 37,620 (216)

GARNET – gene set analysis with exploration of annotation relations

BMC Bioinformatics, 2011
Background Gene set analysis is a powerful method of deducing biological meaning for an a priori defined set of genes. Numerous tools have been developed to test statistical enrichment or depletion in specific pathways or gene ontology (GO) terms.
Seo Jihae, Bae Taejeong, Lee Sanghyun, Jang Youngjun, Kim Bumjin, Rho Kyoohyoung, Seo Chaehwa, Lee Jihyun, Kang Hyunjung, Yu Ungsik, Kim Sunghoon, Lee Sanghyuk, Kim Wan Kyu   +12 more
doaj   +1 more source

DROPA: DRIP-seq optimized peak annotator

BMC Bioinformatics, 2019
Background R-loops are three-stranded nucleic acid structures that usually form during transcription and that may lead to gene regulation or genome instability.
Marco Russo, Bruno De Lucca, Tiziano Flati, Silvia Gioiosa, Giovanni Chillemi, Giovanni Capranico   +5 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

The subsystems approach to genome annotation and its use in the Project to Annotate 1000 Genomes

, 2005
Overbeek R, Begley T, Butler RM, et al. The subsystems approach to genome annotation and its use in the Project to Annotate 1000 Genomes. Nucleic Acids Research.
Hanson, Andrew, Olson, Robert, McHardy, Alice C., Goesmann, Alexander ; https://orcid.org/, Osterman, Andrei, Stevens, Rick, Butler, Ralph M, Ruckert, Christian, Pusch, Gordon D, Butler, Ralph M., Disz, Terry, de Crecy-Lagard, Valerie, Frank, Ed D, Fonstein, Michael, Gerdes, Svetlana, Larsen, Niels, Portnoy, Vasiliy, Frank, Ed D., Goesmann, Alexander, Crécy-Lagard, Valérie de, Choudhuri, Jomuna V., McHardy, Alice C, Thiele, Ines, Olsen, Gary, Overbeek, Ross, Meyer, Folker, Ye, Yuzhen, Begley, Tadhg, Pusch, Gordon D., Choudhuri, Jomuna V, Chuang, Han-Yu, Krause, Lutz, Kubal, Michael, Iwata-Reuyl, Dirk, Rodionov, Dmitry A, Cohoon, Matthew, Edwards, Robert, Diaz, Naryttza N., Rodionov, Dmitry A., Neuweger, Heiko, Linke, Burkhard, Zagnitko, Olga, Vassieva, Olga, Glass, Elizabeth M., Diaz, Naryttza, Rückert, Christian ; https://orcid.org/, Glass, Elizabeth M, Jensen, Roy, Jamshidi, Neema, Steiner, Jason, Vonstein, Veronika   +50 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Gene Annotation Easy Viewer (GAEV): Integrating KEGG’s Gene Function Annotations and Associated Molecular Pathways [version 3; peer review: 1 approved, 2 approved with reservations]

F1000Research, 2019
We developed a Gene Annotation Easy Viewer (GAEV) that integrates the gene annotation data from the KEGG (Kyoto Encyclopedia of Genes and Genomes) Automatic Annotation Server.
Trung Huynh, Sen Xu
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Gene annotation and functional annotation of the protein coding genes

, 2022
Gene annotation and functional annotation of the protein coding genes for the genome assembly of Perilla frutescens (Pfru_yukari_1.0; DDBJ accession numbers BRKX01000001 to BRKX01000071).
Keita Tamura (12496780), Hidemasa Bono (476712), Mika Sakamoto (13808677)   +2 more
core   +1 more source

Gene Annotation Easy Viewer (GAEV): Integrating KEGG’s Gene Function Annotations and Associated Molecular Pathways [version 2; referees: 1 approved, 2 approved with reservations]

F1000Research, 2018
We developed a Gene Annotation Easy Viewer (GAEV) that integrates the gene annotation data from the KEGG (Kyoto Encyclopedia of Genes and Genomes) Automatic Annotation Server.
Trung Huynh, Sen Xu
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source