Results 81 to 90 of about 37,620 (216)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Gene annotation summary statistics.

, 2021
Gene annotation summary statistics.
Mengxue Xu (11846894), Rujun Zhou (11846897), Wenli Jiao (11846891), Yiwei Fu (1819771), Zibo Li (1312707), Caiyun Xue (6837773)   +5 more
core   +1 more source

Gene annotation

, 2019
The .gff3 file for gene ...
Ming Fang (88410), Jiahong Wang (407742), Chunqing Ou (6692600), Yanjie Zhang (360019), Song Li (65582), Yanan Zhao (3132906), Shuling Jiang (6692603), Fei Wang (19534), Li Ma (46633)   +8 more
core   +2 more sources

SynGAP: a synteny-based toolkit for gene structure annotation polishing

Genome Biology
Genome sequencing has become a routine task for biologists, but the challenge of gene structure annotation persists, impeding accurate genomic and genetic research.
Fengqi Wu, Yingxiao Mai, Chengjie Chen, Rui Xia   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Gene Ontology (GO) Annotation in Biomedical Literature [PDF]

, 2008
In this paper, we propose an approach for doing Gene Ontology (GO) annotation on biomedical texts. The GO is an effort to create a controlled terminology for labelling gene functions in a more precise.
Gálvez, Carmen
core  

Deep proteogenomics; high throughput gene validation by multidimensional liquid chromatography and mass spectrometry of proteins from the fungal wheat pathogen Stagonospora nodorum

, 2009
Background Stagonospora nodorum, a fungal ascomycete in the class dothideomycetes, is a damaging pathogen of wheat. It is a model for necrotrophic fungi that cause necrotic symptoms via the interaction of multiple effector proteins with cultivar ...
Hane, J., Casey Tammy, Casey, T., Hane, J.K., Solomon Peter S, Tan, Kar-Chun, James K Hane, Oliver, R.P., Tammy Casey, Kar-Chun Tan, Richard Lipscombe, Lipscombe Richard, Oliver Richard P, Oliver, Richard, Tan, K-C, Richard P Oliver, Hane James K, Tan Kar-Chun, Solomon, P., Lipscombe, R., Scott Bringans, Peter S Solomon, Bringans, S., Solomon, P.S., Bringans Scott   +24 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Annotation of Fusarium graminearum (PH-1) version 5.0 [PDF]

, 2017
Fusarium graminearum floral infections are a major risk to the global supply of safe cereal grains. We report updates to the PH-1 reference genome and significant improvements to the annotation.
King, R., Urban, M., Hammond-Kosack, K. E.   +2 more
core   +1 more source