Results 111 to 120 of about 95,204 (199)

The genetic context of blaIMP varies among bacterial families from One Health sources.

open access: yesPLoS ONE
The blaIMP resistance gene encodes a metallo-beta-lactamase in bacteria, which confers reduced susceptibility or resistance to all the beta-lactams, including carbapenems which are critical for treating life-threatening infections.
Susan Vaughn Grooters   +2 more
doaj   +1 more source

Integron gene cassettes harboring novel variants of D-alanine-D-alanine ligase confer high-level resistance to D-cycloserine. [PDF]

open access: yesSci Rep, 2020
Rahman MA   +6 more
europepmc   +1 more source

Resistance integrons. Mini review

open access: yesCaspian Journal of Internal Medicine, 2019
Integrons are a segment of dsDNA that play a major role in bacterial adaptation and evolution. These genetic determinants are known by the presence of three necessary apparatuses: an integrase (intI gene), Pc (a promoter) and attI (a recombination site).
Fariba Akrami   +2 more
doaj  

Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics

open access: yes, 2023
Dulyayangkul P   +17 more
europepmc   +1 more source

EPISOMAL EXPRESSION CASSETTES FOR GENE THERAPY

open access: yes, 2012
The invention consists of episomal expression cassettes for expression of a tran sgene in gene therapy. The expression cassettes consist of regulatory elements of the human cytokeratin gene and a transgene. The invention also includes liposomes for tran sfection of epithelial tissue with the cassettes in treatment of cystic fibrosis, emphyserma ...
openaire   +3 more sources

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