Results 91 to 100 of about 2,576,180 (238)

Analysis of antibiotic resistance gene cassettes in a newly identified Salmonella enterica serovar Gallinarum strain in Korea. [PDF]

Mob DNA, 2023
Tran TQ, Park M, Lee JE, Kim SH, Jeong JH, Choy HE.   +5 more
europepmc   +1 more source

An Immediate‐Response Detection System for γ‐Hydroxybutyrate to Enhance Personal Safety in Social Environments

Advanced Science, EarlyView.
A graphene‐based electrical biosensor enables rapid and highly sensitive detection of GHB at 100 fm in both standard solutions and artificial urine, providing reliable point‐of‐need screening for drug‐facilitated sexual assault. The platform demonstrates strong selectivity, fast response, and a wide dynamic range, supporting accurate detection in ...
Jai Eun An, Jisung Kwak, Kyung Ho Kim, Chaeeun Kim, Sung Eun Seo, Nathaniel S. Hwang, Yong‐Sang Ryu, Hyun Seok Song, Oh Seok Kwon   +8 more
wiley   +1 more source

Integrons in the Age of Antibiotic Resistance: Evolution, Mechanisms, and Environmental Implications: A Review

Microorganisms
Integrons, which are genetic components commonly found in bacteria, possess the remarkable capacity to capture gene cassettes, incorporate them into their structure, and thereby contribute to an increase in genomic complexity and phenotypic diversity ...
Niyaz Ali, Izhar Ali, Ahmad Ud Din, Kashif Akhtar, Bing He, Ronghui Wen   +5 more
doaj   +1 more source

Prevalence, molecular characterization of integrons and its associated gene cassettes in Klebsiella pneumoniae and K. oxytoca recovered from diverse environmental matrices. [PDF]

Sci Rep, 2023
Fadare FT, Fadare TO, Okoh AI.
europepmc   +1 more source

Modulation of Lung Adenocarcinoma by Phosphorylated FOXN3‐Mediated Transcriptional Inactivation of p53

Advanced Science, EarlyView.
In non‐tumorous lung tissues, FOXN3 promotes the transcriptional activation of p53 by facilitating its recruitment to target promoters, thereby suppressing lung tumorigenesis through activation of the p53 signaling pathway. Conversely, in lung adenocarcinoma tissues, hyperphosphorylated FOXN3 dissociates from the promoters of p53‐responsive genes and ...
Jinjin Yu, Jingyu Yu, Suhui Wang, Xinghong Hu, Lele Jin, Nan Wu, Yuhan Ni, Xueying Zhang, Chengling Zhao, Jihong Zhou, Yong Zhang, Baofa Sun, Hongxing Zhang, Chunfu Zheng, Song Guo Zheng, Wei Li, Xinxing Zhu   +16 more
wiley   +1 more source

Genetic Determinants of Antibacterial Resistance Among Nosocomial Escherichia coli Klebsiella spp., and Enterobacter spp. Isolates Collected in Russia within 2003-2007

Антибиотики и Химиотерапия, 2020
Nosocomial bacterial Isolates collected within 2003-2004 (n=411) and 2005-2007 (n=422) were highly resistant to cephalosporins III-IV and antibacterials of other groups (aminoglycosides, fluoroquinolons, chloramphenicol, and co-trimoxazole).
S. D. Pryamchuk, N. K. Fursova, I. V. Abaev, YU. N. Kovalev, N. A. Shishkova, E. I. Pecherskikh, O. V. Korobova, E. I. Astashkin, D. M. Pachkunov, A. N. Kruglov, D. V. Ivanov, S. V. Sidorenko, E. A. Svetoch, I. A. Dyatlov   +13 more
doaj  

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source

Generation of a multipurpose Prdm16 mouse allele by targeted gene trapping

Disease Models & Mechanisms, 2017
Gene trap mutagenesis is a powerful tool to create loss-of-function mutations in mice and other model organisms. Modifications of traditional gene trap cassettes, including addition of conditional features in the form of Flip-excision (FlEx) arrays to ...
Alexander Strassman, Frank Schnütgen, Qi Dai, Jennifer C. Jones, Angela C. Gomez, Lenore Pitstick, Nathan E. Holton, Russell Moskal, Erin R. Leslie, Harald von Melchner, David R. Beier, Bryan C. Bjork   +11 more
doaj   +1 more source

Introduction of Modified BglBrick System in Lactococcus lactis for Straightforward Assembly of Multiple Gene Cassettes. [PDF]

Front Bioeng Biotechnol, 2021
Plavec TV, Ključevšek T, Berlec A.
europepmc   +1 more source

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

Advanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang, Yu Geng, Xinyu Guo, Chen Wang, Yongjing Sun, Luqi Liu, Li Liu, QianQian Gao, XinFang Zhu, Hongxiang Cao, Gengshuo Zhang, Yunxia Liu, Guobin Zhang, Baoyin Chen, Jinfei Zhang, Xin Hou, Xiaoming Li, Dajian Zhang   +17 more
wiley   +1 more source