Results 81 to 90 of about 2,576,180 (238)

Distribution of isolates positive for ESBL gene, integron and gene cassettes among phylogenetic groups of E. coli.

, 2016
Distribution of isolates positive for ESBL gene, integron and gene cassettes among phylogenetic groups of E. coli.
Saumya Raychaudhuri (470459), Chetna Dureja (2220175), Sakshi Mahajan (2220178)   +2 more
core   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Repository of Antibiotic resistance Cassettes / other gene cassettes

The cassette repository was compiled from a previous review (Partridge SR, Tsafnat G, Coiera E et al. Gene cassettes and cassette arrays in mobile resistance integrons.

core   +1 more source

Auto‐Downregulation of the Florigen FT Production Prevents Precocious Flowering in Plants

Advanced Science, EarlyView.
This study shows that the leaf vein‐expressed FD complexes with the florigen FT to bind DNA motifs in FT promoter, which antagonizes CONSTANS‐mediated FT activation to feedback down‐regulate FT expression. This prevents an excessive induction of FT expression by inductive photoperiods, thereby precluding precocious transition to flowering in ...
Shu Tian, Xiao Luo, Bowen Cui, Yuehui He
wiley   +1 more source

Characterization of antibiotic resistance genes and mobile genetic elements in Escherichia coli isolated from captive black bears

Scientific Reports
The objective of this study was to analyze the antimicrobial resistance (AMR) characteristics produced by antibiotic resistance genes (ARGs), mobile genetic elements (MGEs) and gene cassettes in Escherichia coli isolated from the feces of captive black ...
Hang Liu, Keyun Shi, Yuhan Wang, Wenhao Zhong, Shulei Pan, Lei Zhou, Yuehong Cheng, Yu Yuan, Ziyao Zhou, Haifeng Liu, Shaqiu Zhang, Guangneng Peng, Qigui Yan, Yan Luo, Xiaoli Zhang, Zhijun Zhong   +15 more
doaj   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

Gene cassettes and cassettearrays inmobile resistance integrons

, 2009
antibiotic resistance; nomenclature; bioinformatics; computer-aided discovery. Gene cassettes are small mobile elements, consisting of little more than a single gene and recombination site, which are captured by larger elements called integrons.
Jonathan R. Iredell, Sally R. Partridge, Guy Tsafnat, Enrico Coiera   +3 more
core  

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

Advanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang, Yupo Wu, Jiachang Hou, Lixia Gao, Longqi Pan, Cuicui Shen, Chuanji Zhao, Feng Gao, Yi Zhang, Li Ren, Xiaoping Fang, Xiaoling Dun, Shengyi Liu, Lijiang Liu   +13 more
wiley   +1 more source

Identification and characterization of class 1 integrons among atypical enteropathogenic Escherichia coli isolated from children under 5 years of age

Iranian Journal of Microbiology, 2014
Background and Objectives: The therapeutic options for diseases caused by Escherichia coli are limited. In this study we investigated the presence of virulence factors among Enteropathogenic Escherichia coli (EPEC) strains and their antibiotic resistance
Farzad Shahcheraghi, Fatemeh Rahmati Ghezelgeh, Saman Nobari, Elham Torabi, Seyed-Fazlollah Mousavi, Mohammad Mehdi Aslani, Fereshteh Shahcheraghi   +6 more
doaj  

Belt and braces: Two escape ways to maintain the cassette reservoir of large chromosomal integrons.

PLoS Genetics
Integrons are adaptive devices that capture, stockpile, shuffle and express gene cassettes thereby sampling combinatorial phenotypic diversity. Some integrons called sedentary chromosomal integrons (SCIs) can be massive structures containing hundreds of ...
Egill Richard, Baptiste Darracq, Eloi Littner, Gael A Millot, Valentin Conte, Thomas Cokelaer, Jan Engelstädter, Eduardo P C Rocha, Didier Mazel, Céline Loot   +9 more
doaj   +1 more source