Results 11 to 20 of about 2,666,439 (212)

Investigation of the role of t(4;6) and 6q15 deletion in prostate cancer development and progression [PDF]

, 2010
PhDThe recent identification of TMPRSS2:ETS gene fusions highlighted the importance of chromosomal rearrangement and fusion gene development in prostate tumourigenesis.
Shan, Ling
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Association of the CCR5 gene with juvenile idiopathic arthritis [PDF]

, 2010
The CC chemokine receptor 5 (CCR5) has been shown to be important in the recruitment of T-helper cells to the synovium, where they accumulate, drive the inflammatory process and the consequent synovitis and joint destruction.
Martin, P., BSPAR Study Group, Barton, A., UKRAG Consortium, Worthington, J., Gardner-Medwin, J. [CAPS and BSPAR Study Groups], Thomson, W., W Thomson, Flynn, E., A Hinks, E Flynn, J Packham, Packham, J., Hinks, A., S Eyre, J Worthington, Eyre, S.; id_orcid, Eyre, S., Barton, A.; id_orcid, P Martin, Childhood Arthritis Prospective Study (CAPS), Martin, P.; id_orcid, A Barton   +22 more
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srdA mutations suppress the rseA/cpsA deletion mutant conidiation defect in Aspergillus nidulans

Scientific Reports, 2023
Conidiation is an important reproductive process in Aspergillus. We previously reported, in A. nidulans, that the deletion of a putative glycosyltransferase gene, rseA/cpsA, causes an increase in the production of extracellular hydrolases and a severe ...
Masahiro Ogawa, Ryouichi Fukuda, Ryo Iwama, Yasuji Koyama, Hiroyuki Horiuchi   +4 more
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Construction and characterization of a glycoprotein E deletion mutant of bovine herpesvirus type 1.2 strain isolated in Brazil [PDF]

, 2002
This paper describes the construction and characterization of a Brazilian strain of bovine herpesvirus type 1.2a (BoHV-1.2a) with a deletion of the glycoprotein E (gE) gene. The deletion was introduced by co-transfection of a deletion fragment containing
Rijsewijk, F.A.M., Franco, A.C., Flores, E.F., Weiblen, R., Roehe, P.M.   +4 more
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Rac1 Deletion Causes Thymic Atrophy [PDF]

, 2011
The thymic stroma supports T lymphocyte development and consists of an epithelium maintained by thymic epithelial progenitors. The molecular pathways that govern epithelial homeostasis are poorly understood.
Glogauer Michael, Wright, Nick A, Geoff Laurent, Watt, FM, Janes, Sam M., Kristin M Braun, Emma Nye, Potton, E, Braun, Kristin M., Fiona M. Watt, Janes, Sam M, Katrina McNulty, Butler, Colin, Potton Elspeth, Glogauer, Michael, Wright, NA, Colin Butler, Benitah, Salvador Aznar, Potton, Elspeth, Aznar Benitah Salvador, Boyd, Richard, Jensen, K, Richard Boyd, Braun, Kristin M, Salvador Aznar Benitah, Butler Colin, Sam M Janes, Hunziker, L, Laurent, G, McNulty, Katrina, Elspeth Potton, Janes Sam M., Watt, Fiona M; id_orcid, Boyd, R, Nick A Wright, Kristin M. Braun, Nye, Emma, Laurent Geoff, Michael Glogauer, Wright Nick A., Nye, E, Butler, C, Braun, Kristin, Jensen Kim, Nye Emma, Wright, Nick A., McNulty, Ksatrina, Lukas Hunziker, Glogauer, M, McNulty Katrina, Sam M. Janes, Braun, KM, Laurent, Geoff, Hunziker Lukas, Watt, Fiona, Kim Jensen, Benitah, SA, Nick A. Wright, Watt Fiona M., McNulty, K, Boyd Richard, Fiona M Watt, Wright, Nick, Braun Kristin M., Watt, Fiona M., Jensen, Kim, Janes, SM, Hunziker, Lukas, Aznar Benitah, Salvador, Benitah, Salvador, Janes, Sam   +70 more
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Targeted deletion of HIF-1alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival. [PDF]

, 2007
Sepsis patients may die either from an overwhelming systemic immune response and/or from an immunoparalysis-associated lack of anti-bacterial immune defence. We hypothesized that bacterial superantigen-activated T cells may be prevented from contribution
Kreth Simone, Sitkovsky Michail V., Sitkovsky, Michail V., Alex B Lentsch, Lukashev, Dmitry, Lentsch Alex B., Michail V Sitkovsky, Kreth, Simone, Smith Patrick, Smith, Patrick, Kuboki, Satoshi, P Chen, Caldwell Charles C., Lukashev Dmitry, Akio Ohta, Manfred Thiel, Chen P., Caldwell, Charles C., Lentsch, Alex B., Dmitry Lukashev, Chen, P., Patrick Smith, Kuboki Satoshi, Satoshi Kuboki, Thiel, Manfred, Ohta, Akio, Thiel Manfred, Ohta Akio, Charles C Caldwell, Simone Kreth   +29 more
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Enhancement of Cellulase Production in Trichoderma reesei via Disruption of Multiple Protease Genes Identified by Comparative Secretomics

Frontiers in Microbiology, 2019
The filamentous fungus Trichoderma reesei is one of the most studied cellulolytic organisms and the major producer of cellulases for industrial applications.
Yuanchao Qian, Lixia Zhong, Yu Sun, Ningning Sun, Lei Zhang, Weifeng Liu, Yinbo Qu, Yaohua Zhong   +7 more
doaj   +1 more source

Mycobacterium tuberculosis acg Gene Is Required for Growth and Virulence In Vivo. [PDF]

, 2011
Mycobacterium tuberculosis dosRS two-component regulatory system controls transcription of approximately 50 genes including hspX, acg and Rv2030c, in response to hypoxia and nitric oxide conditions and within macrophages and mice.
Hu, Y, Yanmin Hu, Hu Yanmin, Anthony R M Coates, Anthony R. M. Coates, Coates, AR, Coates Anthony R. M.   +6 more
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Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions from Persons with Symptomatic Malaria Infection in Ethiopia, Kenya, Madagascar, and Rwanda

Emerging Infectious Diseases, 2022
Histidine-rich protein 2 (HRP2)–based rapid diagnostic tests detect Plasmodium falciparum malaria and are used throughout sub-Saharan Africa. However, deletions in the pfhrp2 and related pfhrp3 (pfhrp2/3) genes threaten use of these tests.
Eric Rogier, Jessica N. McCaffery, Doug Nace, Samaly Souza Svigel, Ashenafi Assefa, Jimee Hwang, Simon Kariuki, Aaron M. Samuels, Nelli Westercamp, Arsène Ratsimbasoa, Milijaona Randrianarivelojosia, Aline Uwimana, Venkatachalam Udhayakumar, Eric S. Halsey   +13 more
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Angiotensin-converting enzyme insertion/deletion polymorphism does not influence the restenosis rate after coronary stent implantation [PDF]

, 2002
Background. Experimental studies have shown an activation of the angiotensin-converting enzyme (ACE) system as a response to endothelial injury. Recent publications have elucidated the hypothesis that the ACE gene polymorphism may influence the level of ...
Hausmann, Dirk, Koschyk, Dietmar H., Grip, Lars, Ferrari, Markus, de Jaegere, Peter, Rieber, Johannes, Figulla, Hans R., Mudra, Harald, Schächinger, Volker, Rothman, Martin, Voudris, Vassilis   +10 more
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