Results 231 to 240 of about 7,162,706 (382)

Horizontal gene transfer and gene dosage drives adaptation to wood colonization in a tree pathogen

Proceedings of the National Academy of Sciences of the United States of America, 2015
Braham Dhillon, N. Feau, A. Aerts, Stéphanie Beauseigle, L. Bernier, A. Copeland, A. Foster, N. Gill, B. Henrissat, Padmini Herath, K. Labutti, A. Levasseur, E. Lindquist, Eline A. M. Majoor, R. Ohm, Jasmyn Pangilinan, Amadeus Pribowo, J. Saddler, M. Sakalidis, R. D. de Vries, I. Grigoriev, S. B. Goodwin, P. Tanguay, R. Hamelin   +23 more
semanticscholar   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Determination of Gene Dosage by a Quantitative Adaptation of the Polymerase Chain Reaction (gd-PCR): Rapid Detection of Deletions and Duplications of Gene Sequences

, 1994
Francesco S. Celi, Maimon M. Cohen, Stylianos E. Antonarakis, Efrat Wertheimer, Jesse Roth, Alan R. Shuldiner   +5 more
openalex   +1 more source

A Spectrum of FOXC1 Mutations Suggests Gene Dosage as a Mechanism for Developmental Defects of the Anterior Chamber of the Eye [PDF]

, 2001
Darryl Nishimura, Charles Searby, Wallace L.M. Alward, David S. Walton, Jamie E. Craig, David A. Mackey, Kazuhide Kawase, Adam B. Kanis, Shivanand R. Patil, Edwin M. Stone, Val C. Sheffield   +10 more
openalex   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

Reduced Gene Dosage of the Psychiatric Risk Gene <i>Cacna1c</i> Is Associated with Impairments in Hypothalamic-Pituitary-Adrenal Axis Activity in Rats. [PDF]

Int J Mol Sci
Moon AL, Mawson ER, Gasalla P, Wilkinson LS, Dwyer DM, Hall J, Thomas KL.   +6 more
europepmc   +1 more source

Age, brain region, and gene dosage-differential transcriptomic changes in Shank3-mutant mice. [PDF]

Front Mol Neurosci, 2022
Yoo T, Yoo YE, Kang H, Kim E.
europepmc   +1 more source

Improvement in microbial production of L-tyrosine by gene dosage effect of AroL gene encoding shikimate kinase.

, 1990
Hisao Ito, Katsuaki Sato, Hitoshi Enei, Yoshio Hirose   +3 more
openalex   +2 more sources

Recruitment of the Male-specific Lethal (MSL) Dosage Compensation Complex to an Autosomally Integrated roXChromatin Entry Site Correlates with an Increased Expression of an Adjacent Reporter Gene in Male Drosophila [PDF]

, 2001
Rebecca A. Henry, Birke Andrea Tews, Xuelei Li, Maxwell J. Scott   +3 more
openalex   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source