Results 261 to 270 of about 7,162,706 (382)

Rapid response of fly populations to gene dosage across development and generations. [PDF]

Nat Commun
Li XC, Gandara L, Ekelöf M, Richter K, Alexandrov T, Crocker J.   +5 more
europepmc   +1 more source

Biology in balance: human diploid genome integrity, gene dosage, and genomic medicine. [PDF]

Trends Genet, 2022
Lupski JR.
europepmc   +1 more source

The Emerging 4D Printing of Shape‐Memory Thermomorphs for Self‐Adaptative Biomedical Implants

Advanced Functional Materials, EarlyView.
4D printing enables the creation of smart implants that adapt to changing conditions in the human body over time. At the core of this technology are shape‐memory thermomorphs (SMTMs). This review offers an in‐depth analysis of 4D printing with SMTMs, emphasizing the latest advancements in smart materials, stimuli, programming principles, and their ...
Aixiang Ding, Fang Tang, Eben Alsberg
wiley   +1 more source

A gene dosage-dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH-medulloblastoma. [PDF]

Neuropathol Appl Neurobiol, 2022
Petroni M, Fabretti F, Di Giulio S, Nicolis di Robilant V, La Monica V, Moretti M, Belardinilli F, Bufalieri F, Coppa A, Paci P, Corsi A, De Smaele E, Coni S, Canettieri G, Di Marcotullio L, Wang ZQ, Giannini G.   +16 more
europepmc   +1 more source

AppGene Dosage Modulates Endosomal Abnormalities of Alzheimer's Disease in a Segmental Trisomy 16 Mouse Model of Down Syndrome [PDF]

, 2003
Anne M. Cataldo, Suzana Petanceska, Corrinne M. Peterhoff, Nicole B. Terio, Charles J. Epstein, Angela J. Villar, Elaine J. Carlson, Matthias Staufenbiel, Ralph A. Nixon   +8 more
openalex   +1 more source

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source

Genome-Wide Association Study of Sweet Potato Storage Root Traits Using GWASpoly, a Gene Dosage-Sensitive Model. [PDF]

Int J Mol Sci
Bowers RR, Slonecki TJ, Olukolu BA, Yencho GC, Wadl PA.   +4 more
europepmc   +1 more source

The good, the bad, and the ugly: Evolutionary and pathological aspects of gene dosage alterations. [PDF]

PLoS Genet, 2021
Basilicata MF, Keller Valsecchi CI.
europepmc   +1 more source

Regulation of pTα Gene Expression by a Dosage of E2A, HEB, and SCL [PDF]

, 2003
Mathieu Tremblay, Sabine Herblot, Éric Lécuyer, Trang Hoang   +3 more
openalex   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

Advanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan, Ling Li, Celine J. Agnes, Bettina M. Willie, Maryam Tabrizian   +4 more
wiley   +1 more source