Results 91 to 100 of about 6,867,088 (372)
Restriction and Recruitment—Gene Duplication and the Origin and Evolution of Snake Venom Toxins
bioRxiv, 2014 The genetic and genomic mechanisms underlying evolutionary innovations are of fundamental importance to our understanding of animal evolution. Snake venom represents one such innovation and has been hypothesised to have originated and diversified via a ...
A. Hargreaves +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Duplication and expression of Sox genes in spiders [PDF]
BMC Evolutionary Biology, 2018 BACKGROUND: The Sox family of transcription factors is an important part of the genetic 'toolbox' of all metazoans examined to date and is known to play important developmental roles in vertebrates and insects. However, outside the commonly studied Drosophila model little is known about the repertoire of Sox family transcription factors in other ...
Bonatto Paese, Christian L +4 more
openaire +7 more sources
F1000Research, 2023 Gene content in genomes changes through several different processes, with gene duplication being an important contributor to such changes. Gene duplication occurs over a range of scales from individual genes to whole genomes, and the dynamics of this ...
Amanda E. Wilson +5 more
doaj
Phylogenomics of MADS-Box Genes in Plants — Two Opposing Life Styles in One Gene Family
Biology, 2013 The development of multicellular eukaryotes, according to their body plan, is often directed by members of multigene families that encode transcription factors.
Lydia Gramzow, Günter Theißen
doaj +1 more source
Gene Duplication to Reveal Adaptation Clue of Plant to Environmental Stress: a Case Study of NBS-LRR Genes in Soybean [PDF]
, 2016 Genes responsive to the environmental stresses which are retained after small scale duplication are part of plant genome duplication. However, information of duplicated genes that could be adaptive to environmental changes in plant is limited.
Asadi, N. (nFN) +3 more
core
Mutations in the RB1 Gene in Argentine Retinoblastoma Patients and Uncommon Clinical Presentations [PDF]
, 2015 Background: Retinoblastoma, the most common ocular cancer of childhood, is caused by inactivation of the RB1 tumor suppressor gene in the developing retina.
Alonso, Cristina +6 more
core +1 more source
Identifying and removing haplotypic duplication in primary genome assemblies
bioRxiv, 2019 Motivation Rapid development in long read sequencing and scaffolding technologies is accelerating the production of reference-quality assemblies for large eukaryotic genomes.
Dengfeng Guan +5 more
semanticscholar +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
GENE DUPLICATION AND PHYLOGENY IN CLARKIA [PDF]
Evolution, 1979 Direct evidence for the descent of a group of species from a single common ancestor is rarely possible in the absence of fossils. Consequently, phylogenetic taxonomy relies on comparative analysis of morphological, chromosomal, and biochemical characters for evidence of relationship.
N. F. Weeden, Leslie D. Gottlieb
openaire +3 more sources