Results 11 to 20 of about 6,867,088 (372)
Mechanisms of gene duplication and amplification. [PDF]
Cold Spring Harbor Perspectives in Biology, 2015 Changes in gene copy number are among the most frequent mutational events in all genomes and were among the mutations for which a physical basis was first known. Yet mechanisms of gene duplication remain uncertain because formation rates are difficult to
Andrew B. Reams, J. Roth
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Gene duplication and neofunctionalization: POLR3G and POLR3GL [PDF]
Genome Research, 2014 RNA polymerase III (Pol III) occurs in two versions, one containing the POLR3G subunit and the other the closely related POLR3GL subunit. It is not clear whether these two Pol III forms have the same function, in particular whether they recognize the ...
Marianne Renaud +6 more
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Evolution of Gene Duplication in Plants1[OPEN] [PDF]
Plant Physiology, 2016 Ancient duplication events and a high rate of retention of extant pairs of duplicate genes have contributed to an abundance of duplicate genes in plant genomes. These duplicates have contributed to the evolution of novel functions, such as the production of floral structures, induction of disease resistance, and adaptation to stress.
Nicholas Panchy +2 more
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Gene Complexity and Gene Duplicability [PDF]
Current Biology, 2005 Eukaryotic genes are on average more complex than prokaryotic genes in terms of expression regulation, protein length, and protein-domain structure [1-5]. Eukaryotes are also known to have a higher rate of gene duplication than prokaryotes do [6, 7]. Because gene duplication is the primary source of new genes [], the average gene complexity in a genome
Xionglei He, Jianzhi Zhang
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Expectations of Duplicate Gene Retention Under the Gene Duplicability Hypothesis
BMC Ecology and Evolution, 2023 Abstract Background Gene duplication is an important process in evolution. What causes some genes to be retained after duplication and others to be lost is a process not well understood. The most prevalent theory is the gene duplicability hypothesis, that something about the function and number of interacting partners (number of subunits of ...
Amanda E. Wilson, David A. Liberles
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Patterns of gene evolution following duplications and speciations in vertebrates [PDF]
PeerJ, 2020 Background Eukaryotic genes typically form independent evolutionary lineages through either speciation or gene duplication events. Generally, gene copies resulting from speciation events (orthologs) are expected to maintain similarity over time with ...
Kyle T. David +2 more
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Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump. [PDF]
, 2020 The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components.
Górecki, Kamil, McEvoy, Megan M
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Duplicate Genes Contribute to Variability in Abiotic Stress Resistance in Allopolyploid Wheat
Plants, 2023 Gene duplication is a universal biological phenomenon that drives genomic variation and diversity, plays a crucial role in plant evolution, and contributes to innovations in genetic engineering and crop development.
Linying Du, Zhenbing Ma, Hude Mao
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Gene Dosage and Gene Duplicability [PDF]
Genetics, 2008 Abstract The evolutionary process leading to the fixation of newly duplicated genes is not well understood. It was recently proposed that the fixation of duplicate genes is frequently driven by positive selection for increased gene dosage (i.e., the gene dosage hypothesis), because haploinsufficient genes were reported to have more ...
Wenfeng Qian, Jianzhi Zhang
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Phylogenomics: gene duplication, unrecognized paralogy and outgroup choice. [PDF]
PLoS ONE, 2009 Comparative genomics has revealed the ubiquity of gene and genome duplication and subsequent gene loss. In the case of gene duplication and subsequent loss, gene trees can differ from species trees, thus frequent gene duplication poses a challenge for ...
Scott William Roy
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