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Gene duplication and evolution in recurring polyploidization–diploidization cycles in plants
Background The sharp increase of plant genome and transcriptome data provide valuable resources to investigate evolutionary consequences of gene duplication in a range of taxa, and unravel common principles underlying duplicate gene retention. Results We
Xin Qiao +7 more
doaj +2 more sources
Pear is an important fruit crop of the Rosaceae family and has experienced two rounds of ancient whole-genome duplications (WGDs). However, whether different types of gene duplications evolved differently after duplication remains unclear in the pear ...
Xin Qiao +6 more
doaj +2 more sources
Gene Duplication and Protein Evolution in Tick-Host Interactions [PDF]
Ticks modulate their hosts' defense responses by secreting a biopharmacopiea of hundreds to thousands of proteins and bioactive chemicals into the feeding site (tick-host interface).
Ben J. Mans +3 more
openalex +2 more sources
Significance Gene duplication is a major source of evolutionary innovation and is associated with the increases in biological complexity and adaptive radiation. Termites are model social organisms characterized by a sophisticated caste system.
S. Shigenobu +21 more
semanticscholar +1 more source
Gene Duplication and Gene Fusion Are Important Drivers of Tumourigenesis during Cancer Evolution
Chromosomal rearrangement and genome instability are common features of cancer cells in human. Consequently, gene duplication and gene fusion events are frequently observed in human malignancies and many of the products of these events are pathogenic ...
Cian Glenfield, H. Innan
semanticscholar +1 more source
Expression attenuation as a mechanism of robustness against gene duplication
Significance Many studies have focused on the mechanisms of long-term retention of gene duplicates, such as the gain of functions or reciprocal losses.
Diana Ascencio +5 more
semanticscholar +1 more source
Expectations of Duplicate Gene Retention Under the Gene Duplicability Hypothesis
Abstract Background Gene duplication is an important process in evolution. What causes some genes to be retained after duplication and others to be lost is a process not well understood. The most prevalent theory is the gene duplicability hypothesis, that something about the function and number of interacting partners (number of subunits of ...
Amanda E. Wilson, David A. Liberles
openaire +3 more sources
Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump. [PDF]
The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components.
Górecki, Kamil, McEvoy, Megan M
core +2 more sources
Phylogenomics: gene duplication, unrecognized paralogy and outgroup choice. [PDF]
Comparative genomics has revealed the ubiquity of gene and genome duplication and subsequent gene loss. In the case of gene duplication and subsequent loss, gene trees can differ from species trees, thus frequent gene duplication poses a challenge for ...
Scott William Roy
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