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Duplicate Genes Contribute to Variability in Abiotic Stress Resistance in Allopolyploid Wheat
Plants, 2023 Gene duplication is a universal biological phenomenon that drives genomic variation and diversity, plays a crucial role in plant evolution, and contributes to innovations in genetic engineering and crop development.
Linying Du, Zhenbing Ma, Hude Mao
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Promoter evolution of mammalian gene duplicates
BMC Biology, 2023 Background Gene duplication is thought to be a central process in evolution to gain new functions. The factors that dictate gene retention following duplication as well paralog gene divergence in sequence, expression and function have been extensively ...
Evgeny Fraimovitch, Tzachi Hagai
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Can Introns Stabilize Gene Duplication?
Biology, 2022 Gene duplication is considered one of the most important events that determine the evolution of genomes. However, the neo-duplication condition of a given gene is particularly unstable due to recombination events. Several mechanisms have been proposed to
Gioacchino Micheli, Giorgio Camilloni
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Evolution of new enzymes by gene duplication and divergence
The FEBS Journal, 2020 Thousands of new metabolic and regulatory enzymes have evolved by gene duplication and divergence since the dawn of life. New enzyme activities often originate from promiscuous secondary activities that have become important for fitness due to a change ...
S. Copley
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Gene duplication drives genome expansion in a major lineage of Thaumarchaeota
Nature Communications, 2020 Ammonia-oxidising archaea of the phylum Thaumarchaeota are important organisms in the nitrogen cycle, but the mechanisms driving their radiation into diverse ecosystems remain underexplored. Here, existing thaumarchaeotal genomes are complemented with 12
P. O. Sheridan +12 more
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Gene duplicability of core genes is highly consistent across all angiosperms [PDF]
, 2016 Gene duplication is an important mechanism for adding to genomic novelty. Hence, which genes undergo duplication and are preserved following duplication is an important question. It has been observed that gene duplicability, or the ability of genes to be
De Smet, Riet +5 more
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Horizontal transfer, not duplication, drives the expansion of protein families in prokaryotes. [PDF]
PLoS Genetics, 2011 Gene duplication followed by neo- or sub-functionalization deeply impacts the evolution of protein families and is regarded as the main source of adaptive functional novelty in eukaryotes.
Todd J Treangen, Eduardo P C Rocha
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BMC Genomics, 2012 Background Gene duplication has had a major impact on genome evolution. Localized (or tandem) duplication resulting from unequal crossing over and whole genome duplication are believed to be the two dominant mechanisms contributing to vertebrate genome ...
Lu Jianguo +4 more
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Acquisition of new function through gene duplication in the metallocarboxypeptidase family
Scientific Reports, 2023 Gene duplication is a key first step in the process of expanding the functionality of a multigene family. In order to better understand the process of gene duplication and its role in the formation of new enzymes, we investigated recent duplication ...
Daniel Fajardo +2 more
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The Role of Retrotransposons in Gene Family Expansions: Insights from the Mouse \u3ci\u3eAbp\u3c/i\u3e Gene Family [PDF]
, 2013 Background: Retrotransposons have been suggested to provide a substrate for non-allelic homologous recombination (NAHR) and thereby promote gene family expansion. Their precise role, however, is controversial.
Janoušek, Václav +2 more
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