Results 21 to 30 of about 6,833,326 (223)

Acquisition of new function through gene duplication in the metallocarboxypeptidase family

open access: yesScientific Reports, 2023
Gene duplication is a key first step in the process of expanding the functionality of a multigene family. In order to better understand the process of gene duplication and its role in the formation of new enzymes, we investigated recent duplication ...
Daniel Fajardo   +2 more
doaj   +1 more source

The Role of Retrotransposons in Gene Family Expansions: Insights from the Mouse \u3ci\u3eAbp\u3c/i\u3e Gene Family [PDF]

open access: yes, 2013
Background: Retrotransposons have been suggested to provide a substrate for non-allelic homologous recombination (NAHR) and thereby promote gene family expansion. Their precise role, however, is controversial.
Janoušek, Václav   +2 more
core   +2 more sources

Horizontal transfer, not duplication, drives the expansion of protein families in prokaryotes. [PDF]

open access: yesPLoS Genetics, 2011
Gene duplication followed by neo- or sub-functionalization deeply impacts the evolution of protein families and is regarded as the main source of adaptive functional novelty in eukaryotes.
Todd J Treangen, Eduardo P C Rocha
doaj   +1 more source

Gene duplication in an African cichlid adaptive radiation [PDF]

open access: yes, 2014
Background Gene duplication is a source of evolutionary innovation and can contribute to the divergence of lineages; however, the relative importance of this process remains to be determined.
Joyce, Domino A   +12 more
core   +2 more sources

Copy-number changes in evolution: rates, fitness effects and adaptive significance

open access: yesFrontiers in Genetics, 2013
Gene copy-number differences due to gene duplications and deletions are rampant in natural populations and play a crucial role in the evolution of genome complexity.
Vaishali eKatju, Ulfar eBergthorsson
doaj   +1 more source

Magnetosome Gene Duplication as an Important Driver in the Evolution of Magnetotaxis in the Alphaproteobacteria [PDF]

open access: yes, 2019
The evolution of microbial magnetoreception (or magnetotaxis) is of great interest in the fields of microbiology, evolutionary biology, biophysics, geomicrobiology, and geochemistry.
Bazylinski, Dennis A.   +9 more
core   +3 more sources

Parallel reorganization of protein function in the spindle checkpoint pathway through evolutionary paths in the fitness landscape that appear neutral in laboratory experiments. [PDF]

open access: yesPLoS Genetics, 2017
Regulatory networks often increase in complexity during evolution through gene duplication and divergence of component proteins. Two models that explain this increase in complexity are: 1) adaptive changes after gene duplication, such as resolution of ...
Alex N Nguyen Ba   +5 more
doaj   +1 more source

Gene duplication and an accelerated evolutionary rate in 11S globulin genes are associated with higher protein synthesis in dicots as compared to monocots [PDF]

open access: yes, 2012
Background: Seed storage proteins are a major source of dietary protein, and the content of such proteins determines both the quantity and quality of crop yield.
Dunwell, Jim   +3 more
core   +2 more sources

Complexity Insights of the Minimum Duplication Problem [PDF]

open access: yes, 2014
International audienceThe Minimum Duplication problem is a well-known problem in phylogenetics and comparative genomics. Given a set of gene trees, the Minimum Duplication problem asks for a species tree that induces the minimum number of gene ...
Blin, Guillaume   +4 more
core   +3 more sources

Gene Duplication Associated with Increased Fluconazole Tolerance in Candida auris cells of Advanced Generational Age

open access: yesScientific Reports, 2019
Candida auris is an emerging multi-drug resistant yeast that causes systemic infections. Here we show that C. auris undergoes replicative aging (RA) that results from asymmetric cell division and causes phenotypic differences between mother and daughter ...
Somanon Bhattacharya   +3 more
semanticscholar   +1 more source

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