Results 61 to 70 of about 6,833,475 (368)
Frontiers in Genetics, 2021 The annular pancreas (AP) is a congenital anomaly of the pancreas that can cause acute abdominal pain and vomiting after birth. However, the genetic cause of AP is still unknown, and no study has reported AP in patients with 17q12 duplication. This study
Feifan Xiao +23 more
doaj +1 more source
The evolutionary dynamics of the Saccharomyces cerevisiae protein interaction network after duplication [PDF]
, 2008 Gene duplication is an important mechanism in the evolution of protein interaction networks. Duplications are followed by the gain and loss of interactions, rewiring the network at some unknown rate.
A. Presser +33 more
core +3 more sources
G3: Genes, Genomes, Genetics, 2017 Gene and genome duplication are the major sources of biological innovations in plants and animals. Functional and transcriptional divergence between the copies after gene duplication has been considered the main driver of innovations .
Florian Mattenberger +3 more
doaj +1 more source
Plant Direct, 2020 Polyploidization, or whole‐genome duplication, leads to gene expression changes that drive the evolution of many plants and some animals. However, the role of the dosage effect on gene expression changes following genome duplication remains unclear. Here,
Shouli Feng +6 more
doaj +1 more source
Partial duplication of the APBA2 gene in chromosome 15q13 corresponds to duplicon structures. [PDF]
, 2003 BackgroundChromosomal abnormalities affecting human chromosome 15q11-q13 underlie multiple genomic disorders caused by deletion, duplication and triplication of intervals in this region.
Amin, Taneem +4 more
core +2 more sources
PLoS Genetics, 2015 Neofunctionalization following gene duplication is thought to be one of the key drivers in generating evolutionary novelty. A gene duplication in a common ancestor of land plants produced two classes of KNOTTED-like TALE homeobox genes, class I (KNOX1 ...
Chihiro Furumizu +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
Detecting functional divergence after gene duplication through evolutionary changes in posttranslational regulatory sequences. [PDF]
PLoS Computational Biology, 2014 Gene duplication is an important evolutionary mechanism that can result in functional divergence in paralogs due to neo-functionalization or sub-functionalization.
Alex N Nguyen Ba +7 more
doaj +1 more source
Some asymptotic properties of duplication graphs
, 2003 Duplication graphs are graphs that grow by duplication of existing vertices, and are important models of biological networks, including protein-protein interaction networks and gene regulatory networks.
A.-L. Barabási +9 more
core +1 more source
Revealing mammalian evolutionary relationships by comparative analysis of gene clusters [PDF]
, 2012 Many software tools for comparative analysis of genomic sequence data have been released in recent decades. Despite this, it remains challenging to determine evolutionary relationships in gene clusters due to their complex histories involving ...
Abi-Rached +89 more
core +2 more sources