Results 11 to 20 of about 1,893,955 (220)

Rhythmic diel pattern of gene expression in juvenile maize leaf. [PDF]

, 2011
Co-expressed genes belonging to individual clusters are likely to be regulated by common mechanisms. The nocturnal phase of the diurnal cycle involves gross induction of fundamental biochemical processes and should be studied more thoroughly than was ...
Paweł Siedlecki, Jerzy Tiuryn, Biecek Przemysław, Alicja Sobkowiak, Tiuryn, Jerzy, Jan Fronk, Tiuryn Jerzy, Jończyk, Maciej, Maciej Jończyk, Paweł Sowiński, Jończyk Maciej, Sowiński, Paweł, Siedlecki Paweł, Fronk Jan, Fronk, Jan, Joanna Trzcinska-Danielewicz, Biecek, Przemysław, Sowiński Paweł, Sobkowiak Alicja, Sobkowiak, Alicja, Trzcinska-Danielewicz Joanna, Przemysław Biecek, Siedlecki, Paweł, Trzcinska-Danielewicz, Joanna   +23 more
core   +1 more source

The role of DDK and Treslin–MTBP in coordinating replication licensing and pre-initiation complex formation

Open Biology, 2021
Treslin/Ticrr is required for the initiation of DNA replication and binds to MTBP (Mdm2 Binding Protein). Here, we show that in Xenopus egg extract, MTBP forms an elongated tetramer with Treslin containing two molecules of each protein.
Ilaria Volpi, Peter J. Gillespie, Gaganmeet Singh Chadha, J. Julian Blow   +3 more
doaj   +1 more source

Differential timing of gene expression regulation between leptocephali of the two Anguilla eel species in the Sargasso Sea [PDF]

, 2011
The unique life-history characteristics of North Atlantic catadromous eels have long intrigued evolutionary biologists, especially with respect to mechanisms that could explain their persistence as two ecologically very similar but reproductively and ...
Maes, Gregory E., Als, Thomas Damm, Als, Thomas D., Martin Castonguay, Michael M. Hansen, Jérôme St-Cyr, Bernatchez, Louis, Louis Bernatchez, Thomas D. Als, Eric Normandeau, St-Cyr, Jerome, Als, Thomas, Cramb, Gordon, Saint-Cyr, Jérôme, Gordon Cramb, Maes, Gregory, Kalujnaia, S., Hansen, Michael M., Normandeau, Eric, Svetlana Kalujnaia, Hansen, Michael Møller, Kalujnaia, Svetlana, Hansen, Michael, Gregory E. Maes, Castonguay, Martin   +24 more
core   +1 more source

SWI/SNF catalytic subunits’ switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells

Nature Communications, 2018
The mechanism of resistance to EZH2 inhibitors in cancers with inactivating SWI/SNF mutations is unknown. Here, the authors demonstrate that the switch of the SWI/SNF catalytic subunits from SMARCA4 to SMARCA2 drives resistance to EZH2 inhibitors in ...
Shuai Wu, Nail Fatkhutdinov, Takeshi Fukumoto, Benjamin G. Bitler, Pyoung Hwa Park, Andrew V. Kossenkov, Marco Trizzino, Hsin-Yao Tang, Lin Zhang, Alessandro Gardini, David W. Speicher, Rugang Zhang   +11 more
doaj   +1 more source

Opposing Roles of Wild-type and Mutant p53 in the Process of Epithelial to Mesenchymal Transition

Frontiers in Molecular Biosciences, 2022
The central role of an aberrantly activated EMT program in defining the critical features of aggressive carcinomas is well documented and includes cell plasticity, metastatic dissemination, drug resistance, and cancer stem cell-like phenotypes.
Oleg Semenov, Alexandra Daks, Olga Fedorova, Oleg Shuvalov, Nickolai A. Barlev, Nickolai A. Barlev, Nickolai A. Barlev   +6 more
doaj   +1 more source

Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo [PDF]

, 2011
There is increasing evidence for a connection between DNA replication and the expression of adjacent genes. Therefore, this study addressed the question of whether a herpesvirus origin of replication can be used to activate or increase the expression of ...
Mohr, Hermine, Eckhard Wolf, Marlon R. Schneider (160130), Ulrich H Koszinowski, Laura Scrivano (160134), Eckhard Wolf (39870), Koszinowski Ulrich H., Ruzsics, Zsolt, Schnieke Angelika, Christian A. Mohr (160123), Ulrich H. Koszinowski (152143), Marlon R. Schneider, Mohr Hermine, Schneider Marlon R., Dahlhoff, Maik, Hermine Mohr (160119), Zsolt Ruzsics (75383), Simone Kraner-Schreiber, Schneider, Marlon R., Christian A Mohr, Laura Scrivano, Kraner-Schreiber, Simone, Maik Dahlhoff, Simone Kraner-Schreiber (160141), Ruzsics Zsolt, Maik Dahlhoff (160144), Adler Barbara, Koszinowski, Ulrich H., Kraner-Scheiber, Simone, Zsolt Ruzsics, Mohr, Christian A., Kraner-Schreiber Simone, Schnieke, Angelika, Adler, Barbara, Wolf Eckhard, Dahlhoff Maik, Barbara Adler, Ulrich H. Koszinowski, Christian A. Mohr, Mohr Christian A., Scrivano Laura, Wolf, Eckhard, Hermine Mohr, Marlon R Schneider, Scrivano, Laura, Angelika Schnieke (133290), Barbara Adler (160138), Angelika Schnieke   +47 more
core   +1 more source

Structural basis underlying viral hijacking of a histone chaperone complex

Nature Communications, 2016
The Epstein-Barr virus tegument protein BNRF1 is required for the establishment of selective viral gene expression during latency and interacts with the histone chaperone DAXX.
Hongda Huang, Zhong Deng, Olga Vladimirova, Andreas Wiedmer, Fang Lu, Paul M. Lieberman, Dinshaw J. Patel   +6 more
doaj   +1 more source

Efficient and Rapid Analysis of Polysomes and Ribosomal Subunits in Cells and Tissues Using Ribo Mega-SEC

Bio-Protocol, 2021
Polysome profile analysis is a popular method for separating polysomes and ribosomal subunits and is typically achieved using a sucrose density gradient (SDG).
Harunori Yoshikawa, Ramasubramanian Sundaramoorthy, Daniel Mariyappa, Hao Jiang, Angus Lamond   +4 more
doaj   +1 more source

Comparative genetic, proteomic and phosphoproteomic analysis of C. elegans embryos with a focus on ham-1/STOX and pig-1/MELK in dopaminergic neuron development

Scientific Reports, 2017
Asymmetric cell divisions are required for cellular diversity and defects can lead to altered daughter cell fates and numbers. In a genetic screen for C.
Sarah-Lena Offenburger, Dalila Bensaddek, Alejandro Brenes Murillo, Angus I. Lamond, Anton Gartner   +4 more
doaj   +1 more source

The human lncRNA LINC-PINT inhibits tumor cell invasion through a highly conserved sequence element

Genome Biology, 2017
Background It is now obvious that the majority of cellular transcripts do not code for proteins, and a significant subset of them are long non-coding RNAs (lncRNAs).
Oskar Marín-Béjar, Aina M. Mas, Jovanna González, Dannys Martinez, Alejandro Athie, Xabier Morales, Mikel Galduroz, Ivan Raimondi, Elena Grossi, Shuling Guo, Ana Rouzaut, Igor Ulitsky, Maite Huarte   +12 more
doaj   +1 more source