Results 31 to 40 of about 2,019,582 (297)

ISR8/IRF1-AS1 Is Relevant for IFNα and NF-κB Responses

open access: yesFrontiers in Immunology, 2022
The study of the interferon (IFN) α-induced cell transcriptome has shown altered expression of several long non-coding RNAs (lncRNAs). ISR8/IRF1-AS1 (IFN stimulated RNA 8), located close to IFN regulatory factor 1 (IRF1) coding gene, transcribes a lncRNA
Marina Barriocanal   +8 more
doaj   +1 more source

Regulation of gene expression by photosynthetic signals triggered through modified CO2 availability [PDF]

open access: yes, 2006
Wormuth D, Baier M, Kandlbinder A, Scheibe R, Hartung W, Dietz K-J. Regulation of gene expression by photosynthetic signals triggered through modified CO2 availability. BMC PLANT BIOLOGY.
Scheibe Renate   +17 more
core   +1 more source

ARID1A promotes genomic stability through protecting telomere cohesion

open access: yesNature Communications, 2019
Cells with ARID1A mutations exhibit mitotic defects, yet show surprisingly low levels of copy number defects. Here, Zhao et al. resolve this issue by showing that ARID1A loss causes defects in telomere cohesion, which selects against gross alterations in
Bo Zhao   +16 more
doaj   +1 more source

3′UTR of mRNA Encoding CPEB Protein Orb2 Plays an Essential Role in Intracellular Transport in Neurons

open access: yesCells, 2023
Intracellular trafficking plays a critical role in the functioning of highly polarized cells, such as neurons. Transport of mRNAs, proteins, and other molecules to synaptic terminals maintains contact between neurons and ensures the transmission of nerve
Eugene N. Kozlov   +9 more
doaj   +1 more source

Human aldolase C: gene transcriptional regulation and protein functional role [PDF]

open access: yes, 2011
Aldolase C is the brain-specific aldolase isoenzyme. In the human brain, aldolase C messenger and protein are expressed in a stripe-like pattern in the Purkinje cells of the cerebellum, in the inferior olives and in the Goll and Burdach nuclei of the ...
Serio, Laura
core   +1 more source

Optimising the IgG‐degrading enzyme treatment regimen for enhanced adeno‐associated virus transduction in the presence of neutralising antibodies

open access: yesClinical & Translational Immunology, 2022
Objective Pre‐existing neutralising antibodies (NAbs) to adeno‐associated viruses (AAVs) remain an impediment for systemically administered AAV‐mediated gene therapy treatment in many patients, and various strategies are under investigation to overcome ...
Irene Ros‐Gañán   +11 more
doaj   +1 more source

Auxin-regulated gene expression

open access: yesPhilosophical Transactions of the Royal Society of London. B, Biological Sciences, 1986
Abstract During the 1960s a wide range of studies provided an information base that led to the suggestion that auxin-regulated cell processes - especially cell elongation - may be mediated by auxin-regulated gene expression. Indirect evidence from our work, based on the influence of inhibitors of RNA synthesis (e.g. actinomycin D) and
J L, Key   +7 more
openaire   +3 more sources

Investigation of the Basic Steps in the Chromosome Conformation Capture Procedure

open access: yesFrontiers in Genetics, 2021
A constellation of chromosome conformation capture methods (С-methods) are an important tool for biochemical analysis of the spatial interactions between DNA regions that are separated in the primary sequence.
Oleg V. Bylino   +5 more
doaj   +1 more source

Intestinal gene expression in pigs: effects of reduced feed intake during weaning and potential impact of dietary components [PDF]

open access: yes, 2011
The weaning transition is characterised by morphological, histological and microbial changes, often leading to weaning-associated disorders. These intestinal changes can partly be ascribed to the lack of luminal nutrition arising from the reduced feed ...
Bauer, E.   +3 more
core   +1 more source

CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity

open access: yesNature Communications, 2018
CARM1 is an arginine methyltransferase often overexpressed in human cancer. Here, the authors show that EZH2 inhibition suppresses growth in CARM1-expressing epithelial ovarian cancer, and examine the mechanism of how CARM1 promotes EZH2-mediated tumor ...
Sergey Karakashev   +14 more
doaj   +1 more source

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