Results 11 to 20 of about 779,265 (203)

Identification of BvgA-Dependent and BvgA-Independent Small RNAs (sRNAs) in Bordetella pertussis Using the Prokaryotic sRNA Prediction Toolkit ANNOgesic

open access: yesMicrobiology Spectrum, 2021
Noncoding small RNAs (sRNAs) are crucial for the posttranscriptional regulation of gene expression in all organisms and are known to be involved in the regulation of bacterial virulence.
Kyung Moon   +12 more
doaj   +1 more source

Conformational change of the Bordetella response regulator BvgA accompanies its activation of the B. pertussis virulence gene fhaB

open access: yesComputational and Structural Biotechnology Journal, 2022
The BvgAS two-component system regulates virulence gene expression in Bordetella pertussis. Although precise three-dimensional structural information is not available for the response regulator BvgA, its sequence conservation with E.
David Kim   +12 more
doaj   +1 more source

Structure‐Switching RNAs: From Gene Expression Regulation to Small Molecule Detection

open access: yesSmall Structures, 2021
RNA is instrumental to cell life in many aspects, especially gene expression regulation. Among the various known regulatory RNAs, riboswitches are particularly interesting cis‐acting molecules as they do not need cellular factor to achieve their function
Claire Husser   +2 more
semanticscholar   +1 more source

Status quo of tet regulation in bacteria

open access: yesMicrobial Biotechnology, 2022
Summary The tetracycline repressor (TetR) belongs to the most popular, versatile and efficient transcriptional regulators used in bacterial genetics. In the tetracycline (Tc) resistance determinant tet(B) of transposon Tn10, tetR regulates the expression
Ralph Bertram   +2 more
doaj   +1 more source

Optimized gene expression from bacterial chromosome by high-throughput integration and screening

open access: yesScience Advances, 2020
Pathway gene expression from the chromosome is optimized by a method of random site integrations and high-throughput screening. Chromosomal integration of recombinant genes is desirable compared with expression from plasmids due to increased stability ...
T. Saleski   +5 more
semanticscholar   +1 more source

Algorithm for the Reconstruction of Mathematical Frame Models of Bacterial Transcription Regulation

open access: yesMathematics, 2022
Transcription regulation plays an important role in bacterial activity. The operon concept coined by François Jacob and Jacques Monod has had a considerable effect on investigations into gene expression regulation, including modeling.
Tatiana N. Lakhova   +5 more
doaj   +1 more source

An Adaptable and Modular Set of Laboratory Exercises Connecting Genotype to Phenotype in Sporulating Bacillus subtilis

open access: yesJournal of Microbiology & Biology Education, 2021
Practical lab exercises that help students draw connections between genotype and phenotype, and make and test predictions about the identity of mutants, are invaluable in college-level cell biology, genetics, and microbiology courses. While many bacteria
Anna L. McLoon   +2 more
doaj   +1 more source

Metabolic regulation of gene expression by histone lactylation

open access: yesNature, 2019
The Warburg effect, which originally described increased production of lactate in cancer, is associated with diverse cellular processes such as angiogenesis, hypoxia, polarization of macrophages and activation of T cells.
Di Zhang   +23 more
semanticscholar   +1 more source

Epigenetic silencing of host cell defense genes enhances intracellular survival of the rickettsial pathogen Anaplasma phagocytophilum. [PDF]

open access: yesPLoS Pathogens, 2009
Intracellular bacteria have evolved mechanisms that promote survival within hostile host environments, often resulting in functional dysregulation and disease.
Jose C Garcia-Garcia   +3 more
doaj   +1 more source

Lithium-sensing riboswitch classes regulate expression of bacterial cation transporter genes

open access: yesScientific Reports, 2022
AbstractLithium is rare in Earth’s crust compared to the biologically relevant alkali metal cations sodium and potassium but can accumulate to toxic levels in some environments. We report the experimental validation of two distinct bacterial riboswitch classes that selectively activate gene expression in response to elevated Li+ concentrations.
Neil White   +4 more
openaire   +3 more sources

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