Results 11 to 20 of about 779,265 (203)
Noncoding small RNAs (sRNAs) are crucial for the posttranscriptional regulation of gene expression in all organisms and are known to be involved in the regulation of bacterial virulence.
Kyung Moon +12 more
doaj +1 more source
The BvgAS two-component system regulates virulence gene expression in Bordetella pertussis. Although precise three-dimensional structural information is not available for the response regulator BvgA, its sequence conservation with E.
David Kim +12 more
doaj +1 more source
Structure‐Switching RNAs: From Gene Expression Regulation to Small Molecule Detection
RNA is instrumental to cell life in many aspects, especially gene expression regulation. Among the various known regulatory RNAs, riboswitches are particularly interesting cis‐acting molecules as they do not need cellular factor to achieve their function
Claire Husser +2 more
semanticscholar +1 more source
Status quo of tet regulation in bacteria
Summary The tetracycline repressor (TetR) belongs to the most popular, versatile and efficient transcriptional regulators used in bacterial genetics. In the tetracycline (Tc) resistance determinant tet(B) of transposon Tn10, tetR regulates the expression
Ralph Bertram +2 more
doaj +1 more source
Optimized gene expression from bacterial chromosome by high-throughput integration and screening
Pathway gene expression from the chromosome is optimized by a method of random site integrations and high-throughput screening. Chromosomal integration of recombinant genes is desirable compared with expression from plasmids due to increased stability ...
T. Saleski +5 more
semanticscholar +1 more source
Algorithm for the Reconstruction of Mathematical Frame Models of Bacterial Transcription Regulation
Transcription regulation plays an important role in bacterial activity. The operon concept coined by François Jacob and Jacques Monod has had a considerable effect on investigations into gene expression regulation, including modeling.
Tatiana N. Lakhova +5 more
doaj +1 more source
Practical lab exercises that help students draw connections between genotype and phenotype, and make and test predictions about the identity of mutants, are invaluable in college-level cell biology, genetics, and microbiology courses. While many bacteria
Anna L. McLoon +2 more
doaj +1 more source
Metabolic regulation of gene expression by histone lactylation
The Warburg effect, which originally described increased production of lactate in cancer, is associated with diverse cellular processes such as angiogenesis, hypoxia, polarization of macrophages and activation of T cells.
Di Zhang +23 more
semanticscholar +1 more source
Epigenetic silencing of host cell defense genes enhances intracellular survival of the rickettsial pathogen Anaplasma phagocytophilum. [PDF]
Intracellular bacteria have evolved mechanisms that promote survival within hostile host environments, often resulting in functional dysregulation and disease.
Jose C Garcia-Garcia +3 more
doaj +1 more source
Lithium-sensing riboswitch classes regulate expression of bacterial cation transporter genes
AbstractLithium is rare in Earth’s crust compared to the biologically relevant alkali metal cations sodium and potassium but can accumulate to toxic levels in some environments. We report the experimental validation of two distinct bacterial riboswitch classes that selectively activate gene expression in response to elevated Li+ concentrations.
Neil White +4 more
openaire +3 more sources

