Results 11 to 20 of about 369,643 (266)
Dissecting specific and global transcriptional regulation of bacterial gene expression
Molecular Systems Biology, 2013 Gene expression is regulated by specific transcriptional circuits but also by the global expression machinery as a function of growth. Simultaneous specific and global regulation thus constitutes an additional—but often neglected—layer of complexity in ...
Luca Gerosa +3 more
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Post-transcriptional regulation of gene expression in bacterial pathogens by toxin-antitoxin systems [PDF]
Frontiers in Cellular and Infection Microbiology, 2014 Toxin-antitoxin (TA) systems are small genetic elements ubiquitous in prokaryotic genomes that encode toxic proteins targeting various vital cellular functions.
Ralph eBertram, Christopher F Schuster
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Mode of Regulation and the Insulation of Bacterial Gene Expression [PDF]
Molecular Cell, 2012 A gene can be said to be insulated from environmental variations if its expression level depends only on its cognate inducers, and not on variations in conditions. We tested the insulation of the lac promoter of E. coli and of synthetic constructs in which the transcription factor CRP acts as either an activator or a repressor, by measuring their input
Vered Sasson +4 more
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Lithium-sensing riboswitch classes regulate expression of bacterial cation transporter genes
Scientific Reports, 2022 AbstractLithium is rare in Earth’s crust compared to the biologically relevant alkali metal cations sodium and potassium but can accumulate to toxic levels in some environments. We report the experimental validation of two distinct bacterial riboswitch classes that selectively activate gene expression in response to elevated Li+ concentrations.
Neil White +4 more
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Regulation of Bacterial Gene Expression by Transcription Attenuation [PDF]
Microbiology and Molecular Biology Reviews, 2019 A wide variety of mechanisms that control gene expression in bacteria are based on conditional transcription termination. Generally, in these mechanisms, a transcription terminator is located between a promoter and a downstream gene(s), and the efficiency of the terminator is controlled by a regulatory effector that can be a metabolite, protein, or RNA.
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The bacterial signal molecule, ppGpp, regulates Salmonella virulence gene expression [PDF]
Molecular Microbiology, 2004 SummaryNumerous, overlapping global regulatory systems mediate the environmental signalling controlling the virulence of Salmonella typhimurium. With both extra‐ and intracellular lifestyles, unravelling the mechanisms involved in regulating Salmonella pathogenesis has been complex.
Javier, Pizarro-Cerdá, Karsten, Tedin
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mBio, 2017 In enteropathogenic Escherichia coli (EPEC), the locus of enterocyte effacement (LEE) encodes a type 3 secretion system (T3SS) essential for pathogenesis.
Hervé Leh +5 more
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Dynamics of immune system gene expression upon bacterial challenge and wounding in a social insect (Bombus terrestris). [PDF]
PLoS ONE, 2011 The innate immune system which helps individuals to combat pathogens comprises a set of genes representing four immune system pathways (Toll, Imd, JNK and JAK/STAT). There is a lack of immune genes in social insects (e.g.
Silvio Erler +2 more
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Regulatory 3′ Untranslated Regions of Bacterial mRNAs
Frontiers in Microbiology, 2017 The untranslated regions (UTRs) of mRNA contain important features that are relevant to the post-transcriptional and translational regulation of gene expression.
Gai-Xian Ren +2 more
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Programmable CRISPR‐Cas transcriptional activation in bacteria
Molecular Systems Biology, 2020 Programmable gene activation enables fine‐tuned regulation of endogenous and synthetic gene circuits to control cellular behavior. While CRISPR‐Cas‐mediated gene activation has been extensively developed for eukaryotic systems, similar strategies have ...
Hsing‐I Ho +3 more
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