Priming by recombinant chicken interleukin-2 induces selective expression of IL-8 and IL-18 mRNA in chicken heterophils during receptor-mediated phagocytosis of opsonized and nonopsonized Salmonella enterica serovar enteritidis [PDF]
, 2003 Heterophils, the principal avian polymorphonuclear leukocytes (PMNs) equivalent to the mammalian neutrophil, function as professional phagocytes against bacterial infections, mediate acute inflammation, and respond to cytokine stimulation to aid in ...
Michael H Kogut +5 more
core +1 more source
Regulatory 3′ Untranslated Regions of Bacterial mRNAs
Frontiers in Microbiology, 2017 The untranslated regions (UTRs) of mRNA contain important features that are relevant to the post-transcriptional and translational regulation of gene expression.
Gai-Xian Ren +2 more
doaj +1 more source
Programmable CRISPR‐Cas transcriptional activation in bacteria
Molecular Systems Biology, 2020 Programmable gene activation enables fine‐tuned regulation of endogenous and synthetic gene circuits to control cellular behavior. While CRISPR‐Cas‐mediated gene activation has been extensively developed for eukaryotic systems, similar strategies have ...
Hsing‐I Ho +3 more
doaj +1 more source
Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast [PDF]
, 2007 Splicing of pre-mRNA is a critical step in mRNA maturation and disturbances cause several genetic disorders. We apply the synthetic tetracycline (tc)-binding riboswitch to establish a gene expression system for conditional tc-dependent control of pre ...
Weigand, Julia E. +3 more
core +1 more source
Impact of Solar Radiation on Gene Expression in Bacteria
Proteomes, 2013 Microorganisms often regulate their gene expression at the level of transcription and/or translation in response to solar radiation. In this review, we present the use of both transcriptomics and proteomics to advance knowledge in the field of bacterial ...
Sabine Matallana-Surget, Ruddy Wattiez
doaj +1 more source
Genome wide expression profiling reveals suppression of host defence responses during colonisation by Neisseria meningitides but not N. lactamica. [PDF]
, 2011 Both Neisseria meningitidis and the closely related bacterium Neisseria lactamica colonise human nasopharyngeal mucosal surface, but only N. meningitidis invades the bloodstream to cause potentially life-threatening meningitis and septicaemia.
Kroll J. Simon +27 more
core +2 more sources
Post-transcriptional regulation of gene expression in Yersinia species
Frontiers in Cellular and Infection Microbiology, 2012 Proper regulation of gene expression is required by bacterial pathogens to respond to continually changing environmental conditions and the host response during the infectious process.
Chelsea A Schiano, Wyndham W Lathem
doaj +1 more source
Multi-target regulation by small RNAs synchronizes gene expression thresholds and may enhance ultrasensitive behavior. [PDF]
PLoS ONE, 2012 Cells respond to external cues by precisely coordinating multiple molecular events. Co-regulation may be established by the so-called single-input module (SIM), where a common regulator controls multiple targets.
Jörn Matthias Schmiedel +2 more
doaj +1 more source
A rapid change in virulence gene expression during the transition from the intestinal lumen into tissue promotes systemic dissemination of Salmonella. [PDF]
, 2010 Bacterial pathogens causing systemic disease commonly evolve from organisms associated with localized infections but differ from their close relatives in their ability to overcome mucosal barriers by mechanisms that remain incompletely understood.
Rüssmann Holger +27 more
core +1 more source
Transcriptional adaptation of shigella flexneri during infection of macrophages and epithelial cells : insights into the strategies of a cytosolic bacterial pathogen [PDF]
, 2004 Shigella flexneri, the etiologic agent of bacillary dysentery, invades epithelial cells as well as macrophages and dendritic cells and escapes into the cytosol soon after invasion.
Hong Liu +19 more
core +4 more sources