Results 11 to 20 of about 379,493 (118)

Transcriptome profiling analysis reveals metabolic changes across various growth phases in Bacillus pumilus BA06

open access: yesBMC Microbiology, 2017
Background Bacillus pumilus can secret abundant extracellular enzymes, and may be used as a potential host for the industrial production of enzymes. It is necessary to understand the metabolic processes during cellular growth.
Lin-Li Han   +8 more
doaj   +1 more source

Bacterial-Chromatin Structural Proteins Regulate the Bimodal Expression of the Locus of Enterocyte Effacement (LEE) Pathogenicity Island in Enteropathogenic Escherichia coli

open access: yesmBio, 2017
In enteropathogenic Escherichia coli (EPEC), the locus of enterocyte effacement (LEE) encodes a type 3 secretion system (T3SS) essential for pathogenesis.
Hervé Leh   +5 more
doaj   +1 more source

Regulatory 3′ Untranslated Regions of Bacterial mRNAs

open access: yesFrontiers in Microbiology, 2017
The untranslated regions (UTRs) of mRNA contain important features that are relevant to the post-transcriptional and translational regulation of gene expression.
Gai-Xian Ren   +2 more
doaj   +1 more source

Programmable CRISPR‐Cas transcriptional activation in bacteria

open access: yesMolecular Systems Biology, 2020
Programmable gene activation enables fine‐tuned regulation of endogenous and synthetic gene circuits to control cellular behavior. While CRISPR‐Cas‐mediated gene activation has been extensively developed for eukaryotic systems, similar strategies have ...
Hsing‐I Ho   +3 more
doaj   +1 more source

Dissecting specific and global transcriptional regulation of bacterial gene expression

open access: yesMolecular Systems Biology, 2013
Gene expression is regulated by specific transcriptional circuits but also by the global expression machinery as a function of growth. Simultaneous specific and global regulation thus constitutes an additional—but often neglected—layer of complexity in ...
Luca Gerosa   +3 more
doaj   +1 more source

Impact of Solar Radiation on Gene Expression in Bacteria

open access: yesProteomes, 2013
Microorganisms often regulate their gene expression at the level of transcription and/or translation in response to solar radiation. In this review, we present the use of both transcriptomics and proteomics to advance knowledge in the field of bacterial ...
Sabine Matallana-Surget, Ruddy Wattiez
doaj   +1 more source

Post-transcriptional regulation of gene expression in Yersinia species

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
Proper regulation of gene expression is required by bacterial pathogens to respond to continually changing environmental conditions and the host response during the infectious process.
Chelsea A Schiano, Wyndham W Lathem
doaj   +1 more source

Multi-target regulation by small RNAs synchronizes gene expression thresholds and may enhance ultrasensitive behavior. [PDF]

open access: yesPLoS ONE, 2012
Cells respond to external cues by precisely coordinating multiple molecular events. Co-regulation may be established by the so-called single-input module (SIM), where a common regulator controls multiple targets.
Jörn Matthias Schmiedel   +2 more
doaj   +1 more source

Post-transcriptional regulation of gene expression in bacterial pathogens by toxin-antitoxin systems

open access: yesFrontiers in Cellular and Infection Microbiology, 2014
Toxin-antitoxin (TA) systems are small genetic elements ubiquitous in prokaryotic genomes that encode toxic proteins targeting various vital cellular functions.
Ralph eBertram, Christopher F Schuster
doaj   +1 more source

A highly conserved sRNA downregulates multiple genes, including a σ54 transcriptional activator, in the virulence mode of Bordetella pertussis

open access: yesmBio
Bacterial small non-coding RNA (sRNAs), together with the RNA chaperone Hfq, post-transcriptionally regulate gene expression by affecting ribosome binding or mRNA stability.
Minji Sim   +14 more
doaj   +1 more source

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