Results 251 to 260 of about 658,370 (310)

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

MicroRNAs as Orchestrators of Immune Responses to Bacterial Infection. [PDF]

Microorganisms
Li L, Xiang Y, Cai Y, Luo F.
europepmc   +1 more source

Coordination of Cyanobacterial Nitrate Assimilation and Photosynthesis by a Novel PsbO‐Interacting Protein PirN

Advanced Science, EarlyView.
PirN was identified as a previously uncharacterized PsbO‐interacting protein specifically induced in nitrate‐grown cyanobacteria. Loss of PirN leads to coordinated downregulation of PsbO and the nitrate reductase NarB, causing decreased PSII activity and impaired growth under nitrate conditions. Complementation with either PsbO or NarB largely restores
Chengcheng Huang, Zhen Xiao, Haitao Ge, Gaojie Wang, Jinghui Dong, Yan Wang, Hang Yang, Xing Wang, Hui Gao, Zhongshu Wang, Huanling Yang, Yuanya Zhang, Xiahe Huang, Wu Xu, Weimin Ma, Wenqiang Yang, Yingchun Wang   +16 more
wiley   +1 more source

The Semantics and Mechanisms of Enhancers and Promoters: "What Is True for <i>E. coli</i> Is True for the Elephant, Only More So". [PDF]

Annu Rev Biochem
Struhl K.
europepmc   +1 more source

Review 1 - Nature (Busby) [PDF]

, 2009
Scarlato, Vincenzo
core  

Engineered Bacteria Factory Integrating Drug Delivery and Antibody Manufacture for Activating the STING Signal Pathway Mediated Tumor Immunotherapy

Advanced Science, EarlyView.
To address the limitations of protein‐based ICIs in applications, this study constructed an engineered bacterium, HRB, capable of expressing aCD47 in hypoxic TME. Through the Schiff base reaction, responsive liposomes (LC) loaded with the STING agonist cGAMP were connected to the surface of bacteria to form HRB@LC.
Peng‐Shuo Dong, Tian Yao, Yong Li, Zi‐Hui Yan, Xiao‐Ting Xie, Jia‐Hua Zou, Kai Cheng, Jin‐Xuan Fan, Yuan‐Di Zhao, Qiu‐Ran Xu   +9 more
wiley   +1 more source

Illuminating the mechanism: gene expression responses to antimicrobial photodynamic therapy. [PDF]

BMC Genomics
Burzyńska N, Woźniak-Pawlikowska A, Rapacka-Zdończyk A, Jaśkiewicz M, Kruszewska-Naczk B, Nakonieczna J, Szcześniak MW, Grinholc M.   +7 more
europepmc   +1 more source

Mechanisms of thermoregulation in <i>Pseudomonas aeruginosa</i>. [PDF]

J Bacteriol
Robinson RE, Goldberg JB.
europepmc   +1 more source

High-throughput transposon sequencing identifies HprR as a key regulator of the LEE operon and virulence in <i>E. coli</i> O157:H7. [PDF]

Virulence
Liu M, Wu P, Luo T, Li L, Wang Y, Qin J, Liu D, Li X, Xiang B, Niu Y, Wang L, Liu B.   +11 more
europepmc   +1 more source

An acetylation-dependent switch underlies host disease tolerance during streptococcal infection. [PDF]

Sci Rep
Paudel SK, Gannavaram S, Caparon MG, Xu W.   +3 more
europepmc   +1 more source