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REGULATION OF BACTERIAL GENE EXPRESSION BY RIBOSWITCHES

Annual Review of Microbiology, 2005
Riboswitches are structured domains that usually reside in the noncoding regions of mRNAs, where they bind metabolites and control gene expression. Like their protein counterparts, these RNA gene control elements form highly specific binding pockets for the target metabolite and undergo allosteric changes in structure. Numerous classes of riboswitches
Wade C, Winkler, Ronald R, Breaker
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Temperature-regulated expression of bacterial virulence genes

Microbes and Infection, 2000
Virulence gene expression in most bacteria is a highly regulated phenomenon, affected by a variety of parameters including osmolarity, pH, ion concentration, iron levels, growth phase, and population density. Virulence genes are also regulated by temperature, which acts as an 'on-off' switch in a manner distinct from the more general heat-shock ...
M E, Konkel, K, Tilly
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Crystallization of Hfq protein: a bacterial gene-expression regulator

Acta Crystallographica Section D Biological Crystallography, 2003
Hfq protein from Escherichia coli (EcoHfq) has been overproduced in E. coli, purified to homogeneity and crystallized using the hanging-drop vapour-diffusion technique. Crystallization conditions for EcoHfq were found which yielded X-ray quality crystals.
Vassilieva, Ioulia M.   +4 more
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Regulation of bacterial gene expression by ribosome stalling and rescuing

Current Genetics, 2015
Ribosome is responsible for protein synthesis and is able to monitor the sequence and structure of the nascent peptide. Such ability plays an important role in determining overall gene expression profile of the bacteria through ribosome stalling and rescuing.
Yongxin, Jin, Shouguang, Jin, Weihui, Wu
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In vivo and ex vivo regulation of bacterial virulence gene expression

Current Opinion in Microbiology, 1998
Bacteria are remarkably adaptable organisms that are able to survive and multiply in diverse and sometimes hostile environments. Adaptability is determined by the complement of genetic information available to an organism and by the mechanisms that control gene expression.
P A, Cotter, J F, Miller
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Regulation of bacterial gene expression in response to oxidative stress

1994
Publisher Summary This chapter presents the approaches used to study the regulation of oxidative defense genes in Escherichia coli and Salmonella typhimurium . These general approaches should be useful in examining the response to oxidative stress in other organisms and in further elucidating the response in E. coli and S. typhimurium .
G, Storz, M B, Toledano
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Oxygen intervention in the regulation of gene expression: the photosynthetic bacterial paradigm

Cellular and Molecular Life Sciences (CMLS), 2004
The means by which oxygen intervenes in gene expression has been examined in considerable detail in the metabolically versatile bacterium Rhodobacter sphaeroides. Three regulatory systems are now known in this organism, which are used singly and in combination to modulate genes in response to changing oxygen availability.
J H, Zeilstra-Ryalls, S, Kaplan
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Bacterial expression system with tightly regulated gene expression and plasmid copy number

Gene, 2004
A new Escherichia coli host/vector system has been engineered to allow tight and uniform modulation of gene expression and gamma origin (ori) plasmid copy number. Regulation of gamma ori plasmid copy number is achieved through arabinose-inducible expression of the necessary Rep protein, pi, whose gene was integrated into the chromosome of the host ...
Lisa M, Bowers   +4 more
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Regulation of bacterial gene expression by metal–protein complexes

Molecular Microbiology, 1990
SummaryMetal ions are essential cofactors in several transacting bacterial gene regulators. Upon binding of the metal, the receptor proteins act either as repressors of gene expression or, in other systems, as transcriptional activators. Other metal‐dependent regulatory proteins may function, directly or indirectly, as sensors of the cellular oxygen ...
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Metal Regulation of Gene Expression in Bacterial Systems

1998
Metals are important in biochemical processes (da Silva and Williams, 1991). They can be cofactors of enzymatic reactions or they can be the key redox components of electron transport processes. Zinc is an example of a metal whose properties as a Lewis acid are used in the reactions of a wide variety of catalytic processes, and a quick glance through a
Nigel L. Brown   +3 more
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