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In vivo and ex vivo regulation of bacterial virulence gene expression
Current Opinion in Microbiology, 1998Bacteria are remarkably adaptable organisms that are able to survive and multiply in diverse and sometimes hostile environments. Adaptability is determined by the complement of genetic information available to an organism and by the mechanisms that control gene expression.
P A, Cotter, J F, Miller
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Regulation of bacterial gene expression by metal–protein complexes
Molecular Microbiology, 1990SummaryMetal ions are essential cofactors in several transacting bacterial gene regulators. Upon binding of the metal, the receptor proteins act either as repressors of gene expression or, in other systems, as transcriptional activators. Other metal‐dependent regulatory proteins may function, directly or indirectly, as sensors of the cellular oxygen ...
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Metal Regulation of Gene Expression in Bacterial Systems
1998Metals are important in biochemical processes (da Silva and Williams, 1991). They can be cofactors of enzymatic reactions or they can be the key redox components of electron transport processes. Zinc is an example of a metal whose properties as a Lewis acid are used in the reactions of a wide variety of catalytic processes, and a quick glance through a
Nigel L. Brown +3 more
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Regulation of Bacterial Gene Expression by Protease-Alleviated Spatial Sequestration (PASS)
ACS Synthetic Biology, 2015In natural microbial systems, conditional spatial sequestration of transcription factors enables cells to respond rapidly to changes in their environment or intracellular state by releasing presynthesized regulatory proteins. Although such a mechanism may be useful for engineering synthetic biology technologies ranging from cell-based biosensors to ...
Ragan A, Pitner +2 more
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Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression
Nature, 2002Although proteins fulfil most of the requirements that biology has for structural and functional components such as enzymes and receptors, RNA can also serve in these capacities. For example, RNA has sufficient structural plasticity to form ribozyme and receptor elements that exhibit considerable enzymatic power and binding specificity. Moreover, these
Wade, Winkler +2 more
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Regulation of bacterial gene expression in response to oxidative stress
1994Publisher Summary This chapter presents the approaches used to study the regulation of oxidative defense genes in Escherichia coli and Salmonella typhimurium . These general approaches should be useful in examining the response to oxidative stress in other organisms and in further elucidating the response in E. coli and S. typhimurium .
G, Storz, M B, Toledano
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Regulation of Bacterial Gene Expression
1989The total properties of any bacterium result from an interplay between its genome and its environment. The bacterium Escherichia coli carries approximately 3000 genes, but this total repertoire describes its potential properties and, in reality, only a small subset of this genetic information is expressed at any given moment. A primary influence of the
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DNA Supercoiling as a Regulator of Bacterial Gene Expression
1987Studies of gene expression have advanced to a stage at which we can ask quite detailed questions about the factors that influence transcription and the ways in which these factors interact with each other. Such factors include not only the specific proteins that bind to regulatory sites on DNA, but also more subtle aspects of DNA structure, such as ...
Martin Gellert, Rolf Menzel
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Bacterial Aminoacyl-tRNA Synthetases: Genes and Regulation of Expression
2014Aminoacyl-tRNA synthetases (AARS) form a class of essential enzymes whose main role is to ligate amino acids to tRNAs. This chapter reviews what is known about the AARS genes, their chromosomal localization, their organization, and the regulation of their expression.
Harald Putzer +2 more
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Oxygen intervention in the regulation of gene expression: the photosynthetic bacterial paradigm
Cellular and Molecular Life Sciences (CMLS), 2004The means by which oxygen intervenes in gene expression has been examined in considerable detail in the metabolically versatile bacterium Rhodobacter sphaeroides. Three regulatory systems are now known in this organism, which are used singly and in combination to modulate genes in response to changing oxygen availability.
J H, Zeilstra-Ryalls, S, Kaplan
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