mBio, 2017 In enteropathogenic Escherichia coli (EPEC), the locus of enterocyte effacement (LEE) encodes a type 3 secretion system (T3SS) essential for pathogenesis.
Hervé Leh +5 more
doaj +1 more source
Post-transcriptional regulation of gene expression in Yersinia species
Frontiers in Cellular and Infection Microbiology, 2012 Proper regulation of gene expression is required by bacterial pathogens to respond to continually changing environmental conditions and the host response during the infectious process.
Chelsea A Schiano, Wyndham W Lathem
doaj +1 more source
Programmable CRISPR‐Cas transcriptional activation in bacteria
Molecular Systems Biology, 2020 Programmable gene activation enables fine‐tuned regulation of endogenous and synthetic gene circuits to control cellular behavior. While CRISPR‐Cas‐mediated gene activation has been extensively developed for eukaryotic systems, similar strategies have ...
Hsing‐I Ho +3 more
doaj +1 more source
Tuning Gene Activity by Inducible and Targeted Regulation of Gene Expression in Minimal Bacterial Cells [PDF]
ACS Synthetic Biology, 2018 Functional genomics studies in minimal mycoplasma cells enable unobstructed access to some of the most fundamental processes in biology. Conventional transposon bombardment and gene knockout approaches often fail to reveal functions of genes that are essential for viability, where lethality precludes phenotypic characterization.
Hamilton O. Smith +25 more
openaire +6 more sources
Interaction of two photoreceptors in the regulation of bacterial photosynthesis genes [PDF]
, 2012 The expression of photosynthesis genes in the facultatively photosynthetic bacterium Rhodobacter sphaeroides is controlled by the oxygen tension and by light quantity. Two photoreceptor proteins, AppA and CryB, have been identified in the past, which are
Frühwirth, Sebastian +5 more
core +1 more source
Impact of Solar Radiation on Gene Expression in Bacteria
Proteomes, 2013 Microorganisms often regulate their gene expression at the level of transcription and/or translation in response to solar radiation. In this review, we present the use of both transcriptomics and proteomics to advance knowledge in the field of bacterial ...
Sabine Matallana-Surget, Ruddy Wattiez
doaj +1 more source
Intestinal gene expression in pigs: effects of reduced feed intake during weaning and potential impact of dietary components [PDF]
, 2011 The weaning transition is characterised by morphological, histological and microbial changes, often leading to weaning-associated disorders. These intestinal changes can partly be ascribed to the lack of luminal nutrition arising from the reduced feed ...
Bauer, E. +3 more
core +1 more source
Regulatory 3′ Untranslated Regions of Bacterial mRNAs
Frontiers in Microbiology, 2017 The untranslated regions (UTRs) of mRNA contain important features that are relevant to the post-transcriptional and translational regulation of gene expression.
Gai-Xian Ren +2 more
doaj +1 more source
Multi-target regulation by small RNAs synchronizes gene expression thresholds and may enhance ultrasensitive behavior. [PDF]
PLoS ONE, 2012 Cells respond to external cues by precisely coordinating multiple molecular events. Co-regulation may be established by the so-called single-input module (SIM), where a common regulator controls multiple targets.
Jörn Matthias Schmiedel +2 more
doaj +1 more source
Influence of lipopolysaccharide on proinflammatory gene expression in human corneal, conjunctival and meibomian gland epithelial cells [PDF]
, 2018 PURPOSE: Lipopolysaccharide (LPS), a bacterial endotoxin, is known to stimulate leuokotriene B4 (LTB4) secretion by human corneal (HCECs), conjunctival (HConjECs) and meibomian gland (HMGECs) epithelial cells.
Chen, Di +5 more
core +1 more source