Results 61 to 70 of about 658,370 (310)

Control of Bacterial Sulfite Detoxification by Conserved and Species-Specific Regulatory Circuits

Frontiers in Microbiology, 2019
Although sulfite, a by-product of the degradation of many sulfur compounds, is highly reactive and can cause damage to DNA, proteins and lipids, comparatively little is known about the regulation of sulfite-oxidizing enzyme (SOEs) expression.
Yi Jie Chelsea Tan, Chengzhi Zhao, Marufa Nasreen, Leo O’Rourke, Rabeb Dhouib, Leah Roberts, Ying Wan, Scott A. Beatson, Ulrike Kappler   +8 more
doaj   +1 more source

Do small RNAs unlock the below ground microbiome-plant interaction mystery?

Frontiers in Molecular Biosciences, 2022
Over the past few decades, regulatory RNAs, such as small RNAs (sRNAs), have received increasing attention in the context of host-microbe interactions due to their diverse roles in controlling various biological processes in eukaryotes.
Roshan Regmi, Roshan Regmi, C. Ryan Penton, C. Ryan Penton, C. Ryan Penton, Jonathan Anderson, Jonathan Anderson, Vadakattu V. S. R. Gupta, Vadakattu V. S. R. Gupta   +8 more
doaj   +1 more source

SpxA1 and SpxA2 act coordinately to fine-tune stress responses and virulence in Streptococcus pyogenes [PDF]

, 2017
SpxA is a unique transcriptional regulator highly conserved among members of the phylum Firmicutes that binds RNA polymerase and can act as an antiactivator. Why some Firmicutes members have two highly similar SpxA paralogs is not understood.
Gary C. Port, Larry S. McDaniel, Michael G. Caparon, Paul R. Tumminello, Zachary T. Cusumano   +4 more
core   +4 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Co-PATHOgenex web application for assessing complex stress responses in pathogenic bacteria

Microbiology Spectrum
Pathogenic bacteria encounter various stressors while residing in the host. They respond through intricate mechanisms of gene expression regulation, ensuring their survival and adaptation.
Leyden Fernandez, Martin Rosvall, Johan Normark, Maria Fällman, Kemal Avican   +4 more
doaj   +1 more source

The gut environment regulates bacterial gene expression which modulates susceptibility to bacteriophage infection

Cell Host & Microbe, 2022
Abundance and diversity of bacteria and their viral predators, bacteriophages (phages), in the digestive tract are associated with human health. Particularly intriguing is the long-term coexistence of these two antagonistic populations. We performed genome-wide RNA sequencing on a human enteroaggregative Escherichia coli isolate to identify genes ...
Lourenço, Marta, Chaffringeon, Lorenzo, Lamy-Besnier, Quentin, Titécat, Marie, Pédron, Thierry, Sismeiro, Odile, Legendre, Rachel, Varet, Hugo, Coppée, Jean-Yves, Bérard, Marion, de Sordi, Luisa, Debarbieux, Laurent   +11 more
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Transcriptome analysis of Azospirillum lipoferum during its interaction with rice [PDF]

, 2012
The associative symbiosis between Plant Growth Promoting Rhizobacteria of the genus Azospirillum and cereals have mainly been studied from an agronomic and economic point of view, and several studies showed that plant morphological and metabolic changes ...
Borland, Stéphanie, Drogue, Benoit, Prigent-Combaret, Claire, Sanguin, Hervé, Wisniewski-Dyé, Florence   +4 more
core  

Gac two-component system in Pseudomonas syringae pv. tabaci is required for virulence but not for hypersensitive reaction [PDF]

, 2008
Pseudomonas syringae pv. tabaci 6605 causes wildfire disease on host tobacco plants. To investigate the regulatory mechanism of the expression of virulence, Gac two-Component system-defective mutants, Delta gacA and Delta gacS, and a double mutant, Delta
A Bultreys, A Chatterjee, A Schaefer, A Stintzi, B Quinones, B Quinones, C Fuqua, DK Willis, EO King, F Taguchi, F Taguchi, Fumiko Taguchi, J Yu, JW Costerton, Kazuhiro Toyoda, KH McClean, LM Keith, M Castaneda, M Elasri, M Marutani, MD Parkins, Md. Mijan Hossain, MF Alexeyev, Mizuri Marutani, NT Keen, PD Shaw, S Heeb, SL Lopez-Garcia, SM Kirov, ST Chancey, T Kitten, TG Kinscherf, TM Barta, Tomonori Shiraishi, WF Fett, Y Ishiga, Yoshishige Inagaki, Yujiro Ogawa, Yuki Ichinose   +38 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source