Regulation of fungal gene expression via short open reading frames in the mRNA 5′untranslated region [PDF]
SummaryWe review how the expression of fungal mRNAs can be controlled by ribosome interactions with short upstream open reading frames (uORFs) within the 5′untranslated region. The efficiency of uAUG recognition modulates the impact of a uORF but steps during and after translation of the uORF also influence uORF function. The post‐termination behaviour
Cristina Vilela, J. McCarthy
semanticscholar +3 more sources
pH regulation is a major determinant in expression of a fungal penicillin biosynthetic gene. [PDF]
Transcription of the ipnA gene encoding isopenicillin N synthetase, an enzyme of secondary metabolism, is under the control of the pH regulatory system in the fungus Aspergillus nidulans. External alkaline pH or mutations in pacC, the wide domain regulatory gene which mediates pH regulation, override carbon regulation of ipnA transcript levels ...
E. Espeso +3 more
semanticscholar +3 more sources
The COMPASS‐like complex modulates fungal development and pathogenesis by regulating H3K4me3‐mediated targeted gene expression in Magnaporthe oryzae [PDF]
Abstract Histone‐3‐lysine‐4 (H3K4) methylation is catalysed by the multiprotein complex known as the Set1/COMPASS or MLL/COMPASS‐like complex, an element that is highly evolutionarily conserved from yeast to humans.
Sida Zhou +10 more
openaire +3 more sources
Regulatory Roles of Histone Modifications in Filamentous Fungal Pathogens
Filamentous fungal pathogens have evolved diverse strategies to infect a variety of hosts including plants and insects. The dynamic infection process requires rapid and fine-tuning regulation of fungal gene expression programs in response to the changing
Yiling Lai +3 more
doaj +1 more source
Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress [PDF]
Acknowledgments We thank Alexander Johnson (yhb1D/D), Karl Kuchler (sodD/D mutants), Janet Quinn (hog1D/D, hog1/cap1D/D, trx1D/D) and Peter Staib (ssu1D/D) for providing mutant strains.
A Cederlund +51 more
core +11 more sources
Small RNA Analyses of a Ceratobasidium Isolate Infected with Three Endornaviruses
Isolates of three endornavirus species were identified co-infecting an unidentified species of Ceratobasidium, itself identified as a symbiont from within the roots of a wild plant of the terrestrial orchid Pterostylis vittata in Western Australia ...
Chi T. H. Cao +5 more
doaj +1 more source
Overview of fungal terpene synthases and their regulation
Terpenes and terpenoids are a group of isoprene-derived molecules that constitute the largest group of natural products and secondary metabolites produced by living things, with more than 25,000 compounds reported.
R. González-Hernández +3 more
semanticscholar +1 more source
Doxycycline-regulated gene expression in the opportunistic fungal pathogen Aspergillus fumigatus [PDF]
Abstract Background Although Aspergillus fumigatus is an important human fungal pathogen there are few expression systems available to study the contribution of specific genes to the growth and virulence of this opportunistic mould.
Askew David S +3 more
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Light-regulated promoters for tunable, temporal, and affordable control of fungal gene expression [PDF]
Regulatable promoters are important genetic tools, particularly for assigning function to essential and redundant genes. They can also be used to control the expression of enzymes that influence metabolic flux or protein secretion, thereby optimizing product yield in bioindustry.
Kevin K. Fuller +2 more
openaire +2 more sources
SummaryNatural killer (NK) cells play an important role in the first line of defence against viral infections. We have shown earlier that exposure of human peripheral blood mononuclear cells (PBMC) to viruses results in rapid up‐regulation of NK cell activity via interleukin‐15 (IL‐15) induction, and that this mechanism curtails viral infection in ...
Phay Tran +4 more
semanticscholar +4 more sources

